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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNC5C
Full Name:
Netrin receptor UNC5C
Alias:
Protein unc-5 homolog 3;Protein unc-5 homolog C
Type:
Mass (Da):
103146
Number AA:
931
UniProt ID:
O95185
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
R
K
G
L
R
A
T
A
A
R
C
G
L
G
Site 2
T36
A
L
L
S
A
S
G
T
G
S
A
A
Q
D
D
Site 3
S38
L
S
A
S
G
T
G
S
A
A
Q
D
D
D
F
Site 4
S123
G
L
I
V
R
E
V
S
I
E
I
S
R
Q
Q
Site 5
S127
R
E
V
S
I
E
I
S
R
Q
Q
V
E
E
L
Site 6
S411
K
N
H
R
D
F
E
S
D
I
I
D
S
S
A
Site 7
S417
E
S
D
I
I
D
S
S
A
L
N
G
G
F
Q
Site 8
Y454
A
M
Y
R
G
P
V
Y
A
L
H
D
V
S
D
Site 9
S460
V
Y
A
L
H
D
V
S
D
K
I
P
M
T
N
Site 10
T466
V
S
D
K
I
P
M
T
N
S
P
I
L
D
P
Site 11
S468
D
K
I
P
M
T
N
S
P
I
L
D
P
L
P
Site 12
Y482
P
N
L
K
I
K
V
Y
N
T
S
G
A
V
T
Site 13
S485
K
I
K
V
Y
N
T
S
G
A
V
T
P
Q
D
Site 14
T489
Y
N
T
S
G
A
V
T
P
Q
D
D
L
S
E
Site 15
S495
V
T
P
Q
D
D
L
S
E
F
T
S
K
L
S
Site 16
S499
D
D
L
S
E
F
T
S
K
L
S
P
Q
M
T
Site 17
S502
S
E
F
T
S
K
L
S
P
Q
M
T
Q
S
L
Site 18
T506
S
K
L
S
P
Q
M
T
Q
S
L
L
E
N
E
Site 19
S508
L
S
P
Q
M
T
Q
S
L
L
E
N
E
A
L
Site 20
S516
L
L
E
N
E
A
L
S
L
K
N
Q
S
L
A
Site 21
S521
A
L
S
L
K
N
Q
S
L
A
R
Q
T
D
P
Site 22
T526
N
Q
S
L
A
R
Q
T
D
P
S
C
T
A
F
Site 23
S529
L
A
R
Q
T
D
P
S
C
T
A
F
G
S
F
Site 24
T531
R
Q
T
D
P
S
C
T
A
F
G
S
F
N
S
Site 25
S535
P
S
C
T
A
F
G
S
F
N
S
L
G
G
H
Site 26
Y568
Q
G
R
V
Y
E
M
Y
V
T
V
H
R
K
E
Site 27
T576
V
T
V
H
R
K
E
T
M
R
P
P
M
D
D
Site 28
S584
M
R
P
P
M
D
D
S
Q
T
L
L
T
P
V
Site 29
T586
P
P
M
D
D
S
Q
T
L
L
T
P
V
V
S
Site 30
T589
D
D
S
Q
T
L
L
T
P
V
V
S
C
G
P
Site 31
T646
V
G
E
E
N
F
T
T
P
C
Y
I
Q
L
D
Site 32
Y649
E
N
F
T
T
P
C
Y
I
Q
L
D
A
E
A
Site 33
Y667
L
T
E
N
L
S
T
Y
A
L
V
G
H
S
T
Site 34
S693
I
F
G
P
L
C
C
S
S
L
E
Y
S
I
R
Site 35
Y702
L
E
Y
S
I
R
V
Y
C
L
D
D
T
Q
D
Site 36
T707
R
V
Y
C
L
D
D
T
Q
D
A
L
K
E
I
Site 37
S737
K
A
L
H
F
K
G
S
T
H
N
L
R
L
S
Site 38
S744
S
T
H
N
L
R
L
S
I
H
D
I
A
H
S
Site 39
S751
S
I
H
D
I
A
H
S
L
W
K
S
K
L
L
Site 40
S755
I
A
H
S
L
W
K
S
K
L
L
A
K
Y
Q
Site 41
Y761
K
S
K
L
L
A
K
Y
Q
E
I
P
F
Y
H
Site 42
Y767
K
Y
Q
E
I
P
F
Y
H
V
W
S
G
S
Q
Site 43
T780
S
Q
R
N
L
H
C
T
F
T
L
E
R
F
S
Site 44
T782
R
N
L
H
C
T
F
T
L
E
R
F
S
L
N
Site 45
T814
Q
I
F
Q
L
N
C
T
V
S
E
E
P
T
G
Site 46
S816
F
Q
L
N
C
T
V
S
E
E
P
T
G
I
D
Site 47
T835
D
P
A
N
T
I
T
T
V
T
G
P
S
A
F
Site 48
S854
P
I
R
Q
K
L
C
S
S
L
D
A
P
Q
T
Site 49
T861
S
S
L
D
A
P
Q
T
R
G
H
D
W
R
M
Site 50
Y878
H
K
L
N
L
D
R
Y
L
N
Y
F
A
T
K
Site 51
Y881
N
L
D
R
Y
L
N
Y
F
A
T
K
S
S
P
Site 52
T884
R
Y
L
N
Y
F
A
T
K
S
S
P
T
G
V
Site 53
S887
N
Y
F
A
T
K
S
S
P
T
G
V
I
L
D
Site 54
T921
E
E
M
G
R
H
E
T
V
V
S
L
A
A
E
Site 55
S924
G
R
H
E
T
V
V
S
L
A
A
E
G
Q
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation