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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCDH8
Full Name:
Protocadherin-8
Alias:
arcadlin; PAPC; protocadherin 8; protocadherin-8
Type:
Mass (Da):
113020
Number AA:
UniProt ID:
O95206
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007267
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
P
V
R
R
W
G
S
P
C
L
F
P
L
Q
Site 2
S29
W
V
L
S
V
A
Q
S
K
T
V
R
Y
S
T
Site 3
S693
F
R
A
L
L
V
I
S
D
G
G
R
P
P
L
Site 4
T701
D
G
G
R
P
P
L
T
T
T
A
T
V
S
F
Site 5
T702
G
G
R
P
P
L
T
T
T
A
T
V
S
F
V
Site 6
T705
P
P
L
T
T
T
A
T
V
S
F
V
V
T
A
Site 7
S800
G
A
A
G
G
G
A
S
A
P
G
S
P
E
E
Site 8
S804
G
G
A
S
A
P
G
S
P
E
E
A
A
R
G
Site 9
S834
T
G
K
A
P
F
G
S
P
A
A
D
A
P
P
Site 10
S852
A
A
A
E
V
P
G
S
E
G
G
S
A
T
G
Site 11
S856
V
P
G
S
E
G
G
S
A
T
G
E
S
A
C
Site 12
T858
G
S
E
G
G
S
A
T
G
E
S
A
C
H
F
Site 13
S861
G
G
S
A
T
G
E
S
A
C
H
F
E
G
Q
Site 14
Y879
R
G
A
H
A
E
P
Y
G
A
S
P
G
F
G
Site 15
S882
H
A
E
P
Y
G
A
S
P
G
F
G
K
E
P
Site 16
S900
V
A
V
W
K
G
H
S
F
N
T
I
S
G
R
Site 17
S905
G
H
S
F
N
T
I
S
G
R
E
A
E
K
F
Site 18
S913
G
R
E
A
E
K
F
S
G
K
D
S
G
K
G
Site 19
S917
E
K
F
S
G
K
D
S
G
K
G
D
S
D
F
Site 20
S922
K
D
S
G
K
G
D
S
D
F
N
D
S
D
S
Site 21
S927
G
D
S
D
F
N
D
S
D
S
D
I
S
G
D
Site 22
S929
S
D
F
N
D
S
D
S
D
I
S
G
D
A
L
Site 23
S966
G
H
S
D
R
C
W
S
P
S
C
S
G
P
N
Site 24
S968
S
D
R
C
W
S
P
S
C
S
G
P
N
A
H
Site 25
S970
R
C
W
S
P
S
C
S
G
P
N
A
H
P
S
Site 26
S977
S
G
P
N
A
H
P
S
P
H
P
P
A
Q
M
Site 27
S985
P
H
P
P
A
Q
M
S
T
F
C
K
S
T
S
Site 28
T986
H
P
P
A
Q
M
S
T
F
C
K
S
T
S
L
Site 29
S992
S
T
F
C
K
S
T
S
L
P
R
D
P
L
R
Site 30
Y1003
D
P
L
R
R
D
N
Y
Y
Q
A
Q
L
P
K
Site 31
Y1004
P
L
R
R
D
N
Y
Y
Q
A
Q
L
P
K
T
Site 32
T1011
Y
Q
A
Q
L
P
K
T
V
G
L
Q
S
V
Y
Site 33
S1016
P
K
T
V
G
L
Q
S
V
Y
E
K
V
L
H
Site 34
Y1018
T
V
G
L
Q
S
V
Y
E
K
V
L
H
R
D
Site 35
Y1026
E
K
V
L
H
R
D
Y
D
R
T
V
T
L
L
Site 36
T1029
L
H
R
D
Y
D
R
T
V
T
L
L
S
P
P
Site 37
T1031
R
D
Y
D
R
T
V
T
L
L
S
P
P
R
P
Site 38
S1034
D
R
T
V
T
L
L
S
P
P
R
P
G
R
L
Site 39
Y1052
Q
E
I
G
V
P
L
Y
Q
S
P
P
G
R
Y
Site 40
S1054
I
G
V
P
L
Y
Q
S
P
P
G
R
Y
L
S
Site 41
Y1059
Y
Q
S
P
P
G
R
Y
L
S
P
K
K
G
A
Site 42
S1061
S
P
P
G
R
Y
L
S
P
K
K
G
A
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation