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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HTR3B
Full Name:
5-hydroxytryptamine receptor 3B
Alias:
Serotonin receptor 3B
Type:
Mass (Da):
50292
Number AA:
441
UniProt ID:
O95264
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
A
G
I
L
A
T
D
T
H
H
P
Q
D
S
A
Site 2
S30
D
T
H
H
P
Q
D
S
A
L
Y
H
L
S
K
Site 3
Y43
S
K
Q
L
L
Q
K
Y
H
K
E
V
R
P
V
Site 4
Y51
H
K
E
V
R
P
V
Y
N
W
T
K
A
T
T
Site 5
T57
V
Y
N
W
T
K
A
T
T
V
Y
L
D
L
F
Site 6
T58
Y
N
W
T
K
A
T
T
V
Y
L
D
L
F
V
Site 7
S98
E
F
L
S
W
N
S
S
M
F
D
E
I
R
E
Site 8
Y129
E
F
V
D
I
E
R
Y
P
D
L
P
Y
V
Y
Site 9
Y134
E
R
Y
P
D
L
P
Y
V
Y
V
N
S
S
G
Site 10
Y136
Y
P
D
L
P
Y
V
Y
V
N
S
S
G
T
I
Site 11
Y146
S
S
G
T
I
E
N
Y
K
P
I
Q
V
V
S
Site 12
T172
D
V
Q
N
C
S
L
T
F
K
S
I
L
H
T
Site 13
S175
N
C
S
L
T
F
K
S
I
L
H
T
V
E
D
Site 14
S190
V
D
L
A
F
L
R
S
P
E
D
I
Q
H
D
Site 15
S205
K
K
A
F
L
N
D
S
E
W
E
L
L
S
V
Site 16
S211
D
S
E
W
E
L
L
S
V
S
S
T
Y
S
I
Site 17
S213
E
W
E
L
L
S
V
S
S
T
Y
S
I
L
Q
Site 18
S221
S
T
Y
S
I
L
Q
S
S
A
G
G
F
A
Q
Site 19
S295
M
S
N
Q
V
P
R
S
V
G
S
T
P
L
I
Site 20
S298
Q
V
P
R
S
V
G
S
T
P
L
I
G
H
F
Site 21
T346
F
L
C
L
R
G
D
T
D
A
D
R
P
R
V
Site 22
Y368
V
V
T
E
S
S
L
Y
G
E
H
L
A
Q
P
Site 23
T377
E
H
L
A
Q
P
G
T
L
K
E
V
W
S
Q
Site 24
S383
G
T
L
K
E
V
W
S
Q
L
Q
S
I
S
N
Site 25
S387
E
V
W
S
Q
L
Q
S
I
S
N
Y
L
Q
T
Site 26
S389
W
S
Q
L
Q
S
I
S
N
Y
L
Q
T
Q
D
Site 27
Y391
Q
L
Q
S
I
S
N
Y
L
Q
T
Q
D
Q
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation