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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LYPD3
Full Name:
Ly6/PLAUR domain-containing protein 3
Alias:
GPI-anchored metastasis-associated protein C4.4A homologue
Type:
Mass (Da):
35953
Number AA:
346
UniProt ID:
O95274
International Prot ID:
IPI00004310
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0016020
GO:0031224
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
G
A
Q
A
L
E
C
Y
S
C
V
Q
K
A
D
Site 2
S45
Q
K
A
D
D
G
C
S
P
N
K
M
K
T
V
Site 3
T51
C
S
P
N
K
M
K
T
V
K
C
A
P
G
V
Site 4
T62
A
P
G
V
D
V
C
T
E
A
V
G
A
V
E
Site 5
S76
E
T
I
H
G
Q
F
S
L
A
V
R
G
C
G
Site 6
S131
L
D
P
A
G
N
E
S
A
Y
P
P
N
G
V
Site 7
Y133
P
A
G
N
E
S
A
Y
P
P
N
G
V
E
C
Site 8
Y141
P
P
N
G
V
E
C
Y
S
C
V
G
L
S
R
Site 9
T154
S
R
E
A
C
Q
G
T
S
P
P
V
V
S
C
Site 10
S155
R
E
A
C
Q
G
T
S
P
P
V
V
S
C
Y
Site 11
S160
G
T
S
P
P
V
V
S
C
Y
N
A
S
D
H
Site 12
Y162
S
P
P
V
V
S
C
Y
N
A
S
D
H
V
Y
Site 13
Y169
Y
N
A
S
D
H
V
Y
K
G
C
F
D
G
N
Site 14
S212
T
G
P
G
F
T
L
S
G
S
C
C
Q
G
S
Site 15
S214
P
G
F
T
L
S
G
S
C
C
Q
G
S
R
C
Site 16
S219
S
G
S
C
C
Q
G
S
R
C
N
S
D
L
R
Site 17
S223
C
Q
G
S
R
C
N
S
D
L
R
N
K
T
Y
Site 18
T229
N
S
D
L
R
N
K
T
Y
F
S
P
R
I
P
Site 19
Y230
S
D
L
R
N
K
T
Y
F
S
P
R
I
P
P
Site 20
S232
L
R
N
K
T
Y
F
S
P
R
I
P
P
L
V
Site 21
T247
R
L
P
P
P
E
P
T
T
V
A
S
T
T
S
Site 22
T248
L
P
P
P
E
P
T
T
V
A
S
T
T
S
V
Site 23
S251
P
E
P
T
T
V
A
S
T
T
S
V
T
T
S
Site 24
S258
S
T
T
S
V
T
T
S
T
S
A
P
V
R
P
Site 25
S260
T
S
V
T
T
S
T
S
A
P
V
R
P
T
S
Site 26
T266
T
S
A
P
V
R
P
T
S
T
T
K
P
M
P
Site 27
S267
S
A
P
V
R
P
T
S
T
T
K
P
M
P
A
Site 28
T268
A
P
V
R
P
T
S
T
T
K
P
M
P
A
P
Site 29
T269
P
V
R
P
T
S
T
T
K
P
M
P
A
P
T
Site 30
S277
K
P
M
P
A
P
T
S
Q
T
P
R
Q
G
V
Site 31
T279
M
P
A
P
T
S
Q
T
P
R
Q
G
V
E
H
Site 32
S289
Q
G
V
E
H
E
A
S
R
D
E
E
P
R
L
Site 33
T297
R
D
E
E
P
R
L
T
G
G
A
A
G
H
Q
Site 34
S307
A
A
G
H
Q
D
R
S
N
S
G
Q
Y
P
A
Site 35
S309
G
H
Q
D
R
S
N
S
G
Q
Y
P
A
K
G
Site 36
Y312
D
R
S
N
S
G
Q
Y
P
A
K
G
G
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation