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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCNK5
Full Name:
Potassium channel subfamily K member 5
Alias:
Acid-sensitive potassium channel TASK-2; K2p5.1; Potassium channel, subfamily K, member 5; TASK2; TASK-2; TWIK-related acid-sensitive K ch
Type:
Channel, potassium
Mass (Da):
55130
Number AA:
499
UniProt ID:
O95279
International Prot ID:
IPI00029507
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005267
GO:0030955
GO:0005244
PhosphoSite+
KinaseNET
Biological Process:
GO:0007588
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
W
K
E
A
K
K
N
Y
Y
T
Q
K
L
H
L
Site 2
T108
Y
G
N
V
A
P
K
T
P
A
G
R
L
F
C
Site 3
T149
K
R
L
G
Q
F
L
T
K
R
G
V
S
L
R
Site 4
S154
F
L
T
K
R
G
V
S
L
R
K
A
Q
I
T
Site 5
Y190
M
V
T
E
G
W
N
Y
I
E
G
L
Y
Y
S
Site 6
Y223
S
A
N
Y
H
A
L
Y
R
Y
F
V
E
L
W
Site 7
S266
R
R
R
R
R
K
E
S
F
E
S
S
P
H
S
Site 8
S269
R
R
K
E
S
F
E
S
S
P
H
S
R
K
A
Site 9
S270
R
K
E
S
F
E
S
S
P
H
S
R
K
A
L
Site 10
S273
S
F
E
S
S
P
H
S
R
K
A
L
Q
V
K
Site 11
S282
K
A
L
Q
V
K
G
S
T
A
S
K
D
V
N
Site 12
T283
A
L
Q
V
K
G
S
T
A
S
K
D
V
N
I
Site 13
S285
Q
V
K
G
S
T
A
S
K
D
V
N
I
F
S
Site 14
S292
S
K
D
V
N
I
F
S
F
L
S
K
K
E
E
Site 15
S295
V
N
I
F
S
F
L
S
K
K
E
E
T
Y
N
Site 16
T315
I
G
K
K
A
M
K
T
S
G
G
G
E
T
G
Site 17
S316
G
K
K
A
M
K
T
S
G
G
G
E
T
G
P
Site 18
Y347
S
L
V
P
L
V
V
Y
S
K
N
R
V
P
T
Site 19
T354
Y
S
K
N
R
V
P
T
L
E
E
V
S
Q
T
Site 20
S359
V
P
T
L
E
E
V
S
Q
T
L
R
S
K
G
Site 21
T361
T
L
E
E
V
S
Q
T
L
R
S
K
G
H
V
Site 22
S371
S
K
G
H
V
S
R
S
P
D
E
E
A
V
A
Site 23
S384
V
A
R
A
P
E
D
S
S
P
A
P
E
V
F
Site 24
S385
A
R
A
P
E
D
S
S
P
A
P
E
V
F
M
Site 25
Y410
E
P
W
D
A
Q
D
Y
H
P
L
I
F
Q
D
Site 26
S430
V
N
T
E
A
G
L
S
D
E
E
T
S
K
S
Site 27
T434
A
G
L
S
D
E
E
T
S
K
S
S
L
E
D
Site 28
S437
S
D
E
E
T
S
K
S
S
L
E
D
N
L
A
Site 29
S438
D
E
E
T
S
K
S
S
L
E
D
N
L
A
G
Site 30
S448
D
N
L
A
G
E
E
S
P
Q
Q
G
A
E
A
Site 31
S466
L
N
M
G
E
F
P
S
S
S
E
S
T
F
T
Site 32
S467
N
M
G
E
F
P
S
S
S
E
S
T
F
T
S
Site 33
S468
M
G
E
F
P
S
S
S
E
S
T
F
T
S
T
Site 34
S470
E
F
P
S
S
S
E
S
T
F
T
S
T
E
S
Site 35
T471
F
P
S
S
S
E
S
T
F
T
S
T
E
S
E
Site 36
T473
S
S
S
E
S
T
F
T
S
T
E
S
E
L
S
Site 37
S474
S
S
E
S
T
F
T
S
T
E
S
E
L
S
V
Site 38
T475
S
E
S
T
F
T
S
T
E
S
E
L
S
V
P
Site 39
S477
S
T
F
T
S
T
E
S
E
L
S
V
P
Y
E
Site 40
S480
T
S
T
E
S
E
L
S
V
P
Y
E
Q
L
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation