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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VAPB
Full Name:
Vesicle-associated membrane protein-associated protein B/C
Alias:
ALS8; VAMP (vesicle-associated membrane protein)-associated protein B and C; VAMP-associated protein B/C; VAMP-B; VAMP-C; VAP-B; VAP-C
Type:
Mass (Da):
27228
Number AA:
243
UniProt ID:
O95292
International Prot ID:
IPI00006211
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005789
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0048487
GO:0019899
GO:0046982
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
GO:0030968
GO:0045070
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
K
V
E
Q
V
L
S
L
E
P
Q
H
E
L
Site 2
T27
G
P
F
T
D
V
V
T
T
N
L
K
L
G
N
Site 3
T46
N
V
C
F
K
V
K
T
T
A
P
R
R
Y
C
Site 4
Y52
K
T
T
A
P
R
R
Y
C
V
R
P
N
S
G
Site 5
S58
R
Y
C
V
R
P
N
S
G
I
I
D
A
G
A
Site 6
Y78
V
M
L
Q
P
F
D
Y
D
P
N
E
K
S
K
Site 7
S117
K
P
E
D
L
M
D
S
K
L
R
C
V
F
E
Site 8
S142
V
E
I
N
K
I
I
S
T
T
A
S
K
T
E
Site 9
S146
K
I
I
S
T
T
A
S
K
T
E
T
P
I
V
Site 10
T148
I
S
T
T
A
S
K
T
E
T
P
I
V
S
K
Site 11
T150
T
T
A
S
K
T
E
T
P
I
V
S
K
S
L
Site 12
S154
K
T
E
T
P
I
V
S
K
S
L
S
S
S
L
Site 13
S156
E
T
P
I
V
S
K
S
L
S
S
S
L
D
D
Site 14
S158
P
I
V
S
K
S
L
S
S
S
L
D
D
T
E
Site 15
S159
I
V
S
K
S
L
S
S
S
L
D
D
T
E
V
Site 16
S160
V
S
K
S
L
S
S
S
L
D
D
T
E
V
K
Site 17
T164
L
S
S
S
L
D
D
T
E
V
K
K
V
M
E
Site 18
T201
D
G
L
R
M
R
K
T
V
Q
S
N
S
P
I
Site 19
S204
R
M
R
K
T
V
Q
S
N
S
P
I
S
A
L
Site 20
S206
R
K
T
V
Q
S
N
S
P
I
S
A
L
A
P
Site 21
S209
V
Q
S
N
S
P
I
S
A
L
A
P
T
G
K
Site 22
T214
P
I
S
A
L
A
P
T
G
K
E
E
G
L
S
Site 23
S221
T
G
K
E
E
G
L
S
T
R
L
L
A
L
V
Site 24
T222
G
K
E
E
G
L
S
T
R
L
L
A
L
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation