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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FARS2
Full Name:
Phenylalanyl-tRNA synthetase, mitochondrial
Alias:
Phenylalanine--tRNA ligase
Type:
Mass (Da):
52357
Number AA:
451
UniProt ID:
O95363
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
R
G
A
H
A
Y
V
Y
L
V
S
K
A
S
H
Site 2
S18
H
A
Y
V
Y
L
V
S
K
A
S
H
I
S
R
Site 3
S21
V
Y
L
V
S
K
A
S
H
I
S
R
G
H
Q
Site 4
T43
P
P
A
A
E
C
A
T
Q
R
A
P
G
S
V
Site 5
S49
A
T
Q
R
A
P
G
S
V
V
E
L
L
G
K
Site 6
S57
V
V
E
L
L
G
K
S
Y
P
Q
D
D
H
S
Site 7
Y58
V
E
L
L
G
K
S
Y
P
Q
D
D
H
S
N
Site 8
S64
S
Y
P
Q
D
D
H
S
N
L
T
R
K
V
L
Site 9
Y98
E
R
V
K
E
H
F
Y
K
Q
Y
V
G
R
F
Site 10
Y101
K
E
H
F
Y
K
Q
Y
V
G
R
F
G
T
P
Site 11
T107
Q
Y
V
G
R
F
G
T
P
L
F
S
V
Y
D
Site 12
S111
R
F
G
T
P
L
F
S
V
Y
D
N
L
S
P
Site 13
S117
F
S
V
Y
D
N
L
S
P
V
V
T
T
W
Q
Site 14
T121
D
N
L
S
P
V
V
T
T
W
Q
N
F
D
S
Site 15
S137
L
I
P
A
D
H
P
S
R
K
K
G
D
N
Y
Site 16
Y144
S
R
K
K
G
D
N
Y
Y
L
N
R
T
H
M
Site 17
Y145
R
K
K
G
D
N
Y
Y
L
N
R
T
H
M
L
Site 18
T156
T
H
M
L
R
A
H
T
S
A
H
Q
W
D
L
Site 19
Y178
F
L
V
V
G
D
V
Y
R
R
D
Q
I
D
S
Site 20
Y188
D
Q
I
D
S
Q
H
Y
P
I
F
H
Q
L
E
Site 21
S214
A
G
I
K
D
G
E
S
L
Q
L
F
E
Q
S
Site 22
S221
S
L
Q
L
F
E
Q
S
S
R
S
A
H
K
Q
Site 23
S222
L
Q
L
F
E
Q
S
S
R
S
A
H
K
Q
E
Site 24
S224
L
F
E
Q
S
S
R
S
A
H
K
Q
E
T
H
Site 25
T232
A
H
K
Q
E
T
H
T
M
E
A
V
K
L
V
Site 26
S358
K
V
K
F
Q
P
L
S
K
Y
P
A
V
I
N
Site 27
Y360
K
F
Q
P
L
S
K
Y
P
A
V
I
N
D
I
Site 28
S368
P
A
V
I
N
D
I
S
F
W
L
P
S
E
N
Site 29
Y382
N
Y
A
E
N
D
F
Y
D
L
V
R
T
I
G
Site 30
T387
D
F
Y
D
L
V
R
T
I
G
G
D
L
V
E
Site 31
Y418
S
H
C
Y
R
I
T
Y
R
H
M
E
R
T
L
Site 32
T424
T
Y
R
H
M
E
R
T
L
S
Q
R
E
V
R
Site 33
S426
R
H
M
E
R
T
L
S
Q
R
E
V
R
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation