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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IPO7
Full Name:
Importin-7
Alias:
Imp7; Importin 7; RanBP7
Type:
Karyopherin
Mass (Da):
119517
Number AA:
1038
UniProt ID:
O95373
International Prot ID:
IPI00784008
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005643
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0008536
GO:0008565
GO:0005083
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
I
I
E
A
L
R
G
T
M
D
P
A
L
R
E
Site 2
S32
Q
L
N
E
A
H
K
S
L
N
F
V
S
T
L
Site 3
S45
T
L
L
Q
I
T
M
S
E
Q
L
D
L
P
V
Site 4
Y67
L
K
N
M
I
T
Q
Y
W
P
D
R
E
T
A
Site 5
T73
Q
Y
W
P
D
R
E
T
A
P
G
D
I
S
P
Site 6
S79
E
T
A
P
G
D
I
S
P
Y
T
I
P
E
E
Site 7
Y81
A
P
G
D
I
S
P
Y
T
I
P
E
E
D
R
Site 8
T82
P
G
D
I
S
P
Y
T
I
P
E
E
D
R
H
Site 9
Y136
I
V
D
K
I
G
F
Y
L
Q
S
D
N
S
A
Site 10
Y161
Q
L
V
K
N
Y
E
Y
K
K
P
E
E
R
S
Site 11
S168
Y
K
K
P
E
E
R
S
P
L
V
A
A
M
Q
Site 12
S190
D
R
F
I
Q
L
L
S
D
Q
S
D
Q
S
V
Site 13
S193
I
Q
L
L
S
D
Q
S
D
Q
S
V
L
I
Q
Site 14
S196
L
S
D
Q
S
D
Q
S
V
L
I
Q
K
Q
I
Site 15
T234
E
W
I
E
I
L
K
T
V
V
N
R
D
V
P
Site 16
Y275
L
A
R
L
F
E
R
Y
G
S
P
G
N
V
S
Site 17
S277
R
L
F
E
R
Y
G
S
P
G
N
V
S
K
E
Site 18
Y285
P
G
N
V
S
K
E
Y
N
E
F
A
E
V
F
Site 19
Y309
Q
V
L
L
K
V
L
Y
Q
Y
K
E
K
Q
Y
Site 20
Y311
L
L
K
V
L
Y
Q
Y
K
E
K
Q
Y
M
A
Site 21
Y316
Y
Q
Y
K
E
K
Q
Y
M
A
P
R
V
L
Q
Site 22
T325
A
P
R
V
L
Q
Q
T
L
N
Y
I
N
Q
G
Site 23
Y328
V
L
Q
Q
T
L
N
Y
I
N
Q
G
V
S
H
Site 24
T338
Q
G
V
S
H
A
L
T
W
K
N
L
K
P
H
Site 25
Y373
E
L
W
Q
E
D
P
Y
E
Y
I
R
M
K
F
Site 26
Y375
W
Q
E
D
P
Y
E
Y
I
R
M
K
F
D
V
Site 27
S388
D
V
F
E
D
F
I
S
P
T
T
A
A
Q
T
Site 28
S402
T
L
L
F
T
A
C
S
K
R
K
E
V
L
Q
Site 29
T411
R
K
E
V
L
Q
K
T
M
G
F
C
Y
Q
I
Site 30
S438
G
A
L
H
M
I
G
S
L
A
E
I
L
L
K
Site 31
Y449
I
L
L
K
K
K
I
Y
K
D
Q
M
E
Y
M
Site 32
Y471
L
F
S
S
E
L
G
Y
M
R
A
R
A
C
W
Site 33
S490
F
C
E
V
K
F
K
S
D
Q
N
L
Q
T
A
Site 34
S526
I
A
L
Q
V
L
I
S
N
Q
E
K
A
K
E
Site 35
Y534
N
Q
E
K
A
K
E
Y
I
T
P
F
I
R
P
Site 36
T536
E
K
A
K
E
Y
I
T
P
F
I
R
P
V
M
Site 37
T553
L
L
H
I
I
R
E
T
E
N
D
D
L
T
N
Site 38
T559
E
T
E
N
D
D
L
T
N
V
I
Q
K
M
I
Site 39
T574
C
E
Y
S
E
E
V
T
P
I
A
V
E
M
T
Site 40
S601
T
G
P
D
E
E
G
S
D
D
K
A
V
T
A
Site 41
Y652
Q
Q
H
V
L
E
F
Y
E
E
I
F
S
L
A
Site 42
T663
F
S
L
A
H
S
L
T
C
Q
Q
V
S
P
Q
Site 43
Y689
F
Q
Q
D
G
F
D
Y
F
T
D
M
M
P
L
Site 44
T707
Y
V
T
V
D
T
D
T
L
L
S
D
T
K
Y
Site 45
S710
V
D
T
D
T
L
L
S
D
T
K
Y
L
E
M
Site 46
T712
T
D
T
L
L
S
D
T
K
Y
L
E
M
I
Y
Site 47
T770
E
A
A
L
E
R
L
T
R
E
V
K
T
S
E
Site 48
T775
R
L
T
R
E
V
K
T
S
E
L
R
T
M
C
Site 49
S776
L
T
R
E
V
K
T
S
E
L
R
T
M
C
L
Site 50
Y876
F
N
G
L
K
R
A
Y
A
C
H
A
E
H
E
Site 51
S886
H
A
E
H
E
N
D
S
D
D
D
D
E
A
E
Site 52
T898
E
A
E
D
D
D
E
T
E
E
L
G
S
D
E
Site 53
S903
D
E
T
E
E
L
G
S
D
E
D
D
I
D
E
Site 54
Y915
I
D
E
D
G
Q
E
Y
L
E
I
L
A
K
Q
Site 55
T947
T
A
L
E
G
Y
S
T
I
I
D
D
E
D
N
Site 56
Y959
E
D
N
P
V
D
E
Y
Q
I
F
K
A
I
F
Site 57
Y977
Q
N
R
N
P
V
W
Y
Q
A
L
T
H
G
L
Site 58
T997
K
Q
L
Q
D
I
A
T
L
A
D
Q
R
R
A
Site 59
S1008
Q
R
R
A
A
H
E
S
K
M
I
E
K
H
G
Site 60
Y1017
M
I
E
K
H
G
G
Y
K
F
S
A
P
V
V
Site 61
S1020
K
H
G
G
Y
K
F
S
A
P
V
V
P
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation