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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GDF11
Full Name:
Growth/differentiation factor 11
Alias:
Bone morphogenetic protein 11
Type:
Mass (Da):
45091
Number AA:
407
UniProt ID:
O95390
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S48
A
G
V
G
G
E
R
S
S
R
P
A
P
S
V
Site 2
S49
G
V
G
G
E
R
S
S
R
P
A
P
S
V
A
Site 3
S54
R
S
S
R
P
A
P
S
V
A
P
E
P
D
G
Site 4
S71
V
C
V
W
R
Q
H
S
R
E
L
R
L
E
S
Site 5
S78
S
R
E
L
R
L
E
S
I
K
S
Q
I
L
S
Site 6
S81
L
R
L
E
S
I
K
S
Q
I
L
S
K
L
R
Site 7
S85
S
I
K
S
Q
I
L
S
K
L
R
L
K
E
A
Site 8
Y135
D
F
L
E
E
D
E
Y
H
A
T
T
E
T
V
Site 9
T138
E
E
D
E
Y
H
A
T
T
E
T
V
I
S
M
Site 10
S144
A
T
T
E
T
V
I
S
M
A
Q
E
T
D
P
Site 11
Y183
L
K
A
Q
L
W
V
Y
L
R
P
V
P
R
P
Site 12
T192
R
P
V
P
R
P
A
T
V
Y
L
Q
I
L
R
Site 13
S223
R
R
H
I
R
I
R
S
L
K
I
E
L
H
S
Site 14
S230
S
L
K
I
E
L
H
S
R
S
G
H
W
Q
S
Site 15
S232
K
I
E
L
H
S
R
S
G
H
W
Q
S
I
D
Site 16
S237
S
R
S
G
H
W
Q
S
I
D
F
K
Q
V
L
Site 17
T293
E
L
R
V
L
E
N
T
K
R
S
R
R
N
L
Site 18
S296
V
L
E
N
T
K
R
S
R
R
N
L
G
L
D
Site 19
S308
G
L
D
C
D
E
H
S
S
E
S
R
C
C
R
Site 20
Y316
S
E
S
R
C
C
R
Y
P
L
T
V
D
F
E
Site 21
Y336
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Site 22
Y340
P
K
R
Y
K
A
N
Y
C
S
G
Q
C
E
Y
Site 23
S342
R
Y
K
A
N
Y
C
S
G
Q
C
E
Y
M
F
Site 24
S367
Q
Q
A
N
P
R
G
S
A
G
P
C
C
T
P
Site 25
T373
G
S
A
G
P
C
C
T
P
T
K
M
S
P
I
Site 26
Y384
M
S
P
I
N
M
L
Y
F
N
D
K
Q
Q
I
Site 27
Y393
N
D
K
Q
Q
I
I
Y
G
K
I
P
G
M
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation