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Updated November 2019
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Protein Info
Short Name:
PLEKHA9
Full Name:
Protein PLEKHA9
Alias:
Type:
Mass (Da):
43539
Number AA:
391
UniProt ID:
O95397
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
L
V
Q
Q
V
D
K
T
K
E
V
T
T
T
G
Site 2
T24
K
T
K
E
V
T
T
T
G
V
S
N
S
E
E
Site 3
S27
E
V
T
T
T
G
V
S
N
S
E
E
G
I
D
Site 4
S29
T
T
T
G
V
S
N
S
E
E
G
I
D
V
G
Site 5
T37
E
E
G
I
D
V
G
T
L
L
K
S
T
C
N
Site 6
T45
L
L
K
S
T
C
N
T
F
L
K
T
L
E
E
Site 7
Y67
A
F
T
S
E
L
L
Y
H
T
P
P
G
S
P
Site 8
T69
T
S
E
L
L
Y
H
T
P
P
G
S
P
Q
L
Site 9
S73
L
Y
H
T
P
P
G
S
P
Q
L
A
M
L
K
Site 10
S81
P
Q
L
A
M
L
K
S
S
K
M
K
H
P
I
Site 11
S94
P
I
I
P
I
H
N
S
L
E
R
Q
T
E
L
Site 12
T99
H
N
S
L
E
R
Q
T
E
L
S
T
C
E
N
Site 13
S102
L
E
R
Q
T
E
L
S
T
C
E
N
G
S
L
Site 14
S108
L
S
T
C
E
N
G
S
L
N
M
E
I
N
G
Site 15
S126
I
L
M
K
N
K
N
S
L
Y
L
K
S
A
E
Site 16
Y128
M
K
N
K
N
S
L
Y
L
K
S
A
E
I
D
Site 17
S137
K
S
A
E
I
D
C
S
I
S
S
E
E
N
T
Site 18
S139
A
E
I
D
C
S
I
S
S
E
E
N
T
D
D
Site 19
T144
S
I
S
S
E
E
N
T
D
D
N
I
T
V
Q
Site 20
T149
E
N
T
D
D
N
I
T
V
Q
G
E
I
M
K
Site 21
S171
K
N
H
D
N
N
L
S
Q
S
G
S
D
S
S
Site 22
S173
H
D
N
N
L
S
Q
S
G
S
D
S
S
C
S
Site 23
S175
N
N
L
S
Q
S
G
S
D
S
S
C
S
P
E
Site 24
S177
L
S
Q
S
G
S
D
S
S
C
S
P
E
C
L
Site 25
S178
S
Q
S
G
S
D
S
S
C
S
P
E
C
L
W
Site 26
S180
S
G
S
D
S
S
C
S
P
E
C
L
W
E
E
Site 27
T194
E
G
K
E
V
I
P
T
F
F
S
T
M
N
T
Site 28
S204
S
T
M
N
T
S
F
S
D
I
E
L
L
E
D
Site 29
S212
D
I
E
L
L
E
D
S
G
I
P
T
E
A
F
Site 30
Y256
I
K
K
V
N
Q
K
Y
I
T
N
K
E
E
F
Site 31
T265
T
N
K
E
E
F
T
T
L
Q
K
I
V
L
H
Site 32
S284
D
V
A
Q
V
R
N
S
A
T
E
A
L
L
W
Site 33
T304
K
F
L
K
G
F
L
T
E
V
K
N
G
E
K
Site 34
T315
N
G
E
K
D
I
Q
T
A
L
N
N
A
Y
G
Site 35
T355
E
D
F
V
A
A
L
T
V
K
E
G
D
H
R
Site 36
S367
D
H
R
K
E
A
F
S
I
G
M
Q
R
D
L
Site 37
Y377
M
Q
R
D
L
S
L
Y
L
P
A
M
K
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation