PhosphoNET

           
Protein Info 
   
Short Name:  MED26
Full Name:  Mediator of RNA polymerase II transcription subunit 26
Alias:  Activator-recruited cofactor 70 kDa component; ARC70; Cofactor required for Sp1 transcriptional activation 7; CRSP complex 7; CRSP70; Mediator complex subunit 26
Type:  Transcription, coactivator/corepressor
Mass (Da):  65446
Number AA:  600
UniProt ID:  O95402
International Prot ID:  IPI00294682
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016592     Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0016455  GO:0003713 PhosphoSite+ KinaseNET
Biological Process:  GO:0006357  GO:0006367   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7SQSLSRSSQSMDIDG
Site 2S23LQAIDPQSNIRNMVA
Site 3T64INDVRKKTKNEELAK
Site 4S103GLAGATGSANGGAHN
Site 5S123GAAGPPRSIHDLKSR
Site 6S129RSIHDLKSRNDLQRL
Site 7S146QRLDRLGSRKRRGDQ
Site 8S166PGPPPKVSKASHDPL
Site 9S177HDPLVPNSSPLPTNG
Site 10S178DPLVPNSSPLPTNGI
Site 11T182PNSSPLPTNGISGSP
Site 12S186PLPTNGISGSPESFA
Site 13S188PTNGISGSPESFASS
Site 14S191GISGSPESFASSLDG
Site 15S194GSPESFASSLDGSGH
Site 16S195SPESFASSLDGSGHA
Site 17S199FASSLDGSGHAGPEG
Site 18T230VNAVRPHTSSPGLGK
Site 19S231NAVRPHTSSPGLGKP
Site 20S232AVRPHTSSPGLGKPP
Site 21S248PCLQPKASVLQQLDR
Site 22T259QLDRVDETPGPPHPK
Site 23S272PKGPPRCSFSPRNSR
Site 24S274GPPRCSFSPRNSRHE
Site 25S278CSFSPRNSRHEGSFA
Site 26S283RNSRHEGSFARQQSL
Site 27S289GSFARQQSLYAPKGS
Site 28Y291FARQQSLYAPKGSVP
Site 29S296SLYAPKGSVPSPSPR
Site 30S299APKGSVPSPSPRPQA
Site 31S301KGSVPSPSPRPQALD
Site 32T310RPQALDATQVPSPLP
Site 33S314LDATQVPSPLPLAQP
Site 34S322PLPLAQPSTPPVRRL
Site 35T323LPLAQPSTPPVRRLE
Site 36S334RRLELLPSAESPVCW
Site 37S337ELLPSAESPVCWLEQ
Site 38S347CWLEQPESHQRLAGP
Site 39S361PGCKAGLSPAEPLLS
Site 40S368SPAEPLLSRAGFSPD
Site 41S373LLSRAGFSPDSSKAD
Site 42S376RAGFSPDSSKADSDA
Site 43S377AGFSPDSSKADSDAA
Site 44S381PDSSKADSDAASSGG
Site 45S385KADSDAASSGGSDSK
Site 46S386ADSDAASSGGSDSKK
Site 47S389DAASSGGSDSKKKKR
Site 48S391ASSGGSDSKKKKRYR
Site 49Y402KRYRPRDYTVNLDGQ
Site 50T403RYRPRDYTVNLDGQV
Site 51T426RLKERKLTFDPMTRQ
Site 52T431KLTFDPMTRQIKPLT
Site 53T438TRQIKPLTQKEPVRA
Site 54S447KEPVRADSPVHMEQQ
Site 55S467DKQEAKASLQSPFEQ
Site 56S470EAKASLQSPFEQTNW
Site 57S488SRNEIIQSYLSRQSS
Site 58Y489RNEIIQSYLSRQSSL
Site 59S491EIIQSYLSRQSSLLS
Site 60S494QSYLSRQSSLLSSSG
Site 61S495SYLSRQSSLLSSSGA
Site 62S498SRQSSLLSSSGAQTP
Site 63S499RQSSLLSSSGAQTPG
Site 64S500QSSLLSSSGAQTPGA
Site 65T504LSSSGAQTPGAHHFM
Site 66Y514AHHFMSEYLKQEEST
Site 67S520EYLKQEESTRQGARQ
Site 68S535LHVLVPQSPPTDLPG
Site 69T538LVPQSPPTDLPGLTR
Site 70T548PGLTREVTQDDLDRI
Site 71S558DLDRIQASQWPGVNG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation