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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BAG4
Full Name:
BAG family molecular chaperone regulator 4
Alias:
BAG-4; BAG-family molecular chaperone regulator-4; BCL2-associated athanogene 4; Silencer of death domains; SODD
Type:
Uncharacterized protein
Mass (Da):
49594
Number AA:
457
UniProt ID:
O95429
International Prot ID:
IPI00030695
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005057
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
A
L
R
R
S
G
Y
G
P
S
D
G
Site 2
Y9
S
A
L
R
R
S
G
Y
G
P
S
D
G
P
S
Site 3
S12
R
R
S
G
Y
G
P
S
D
G
P
S
Y
G
R
Site 4
S16
Y
G
P
S
D
G
P
S
Y
G
R
Y
Y
G
P
Site 5
Y17
G
P
S
D
G
P
S
Y
G
R
Y
Y
G
P
G
Site 6
Y20
D
G
P
S
Y
G
R
Y
Y
G
P
G
G
G
D
Site 7
Y21
G
P
S
Y
G
R
Y
Y
G
P
G
G
G
D
V
Site 8
Y37
V
H
P
P
P
P
L
Y
P
L
R
P
E
P
P
Site 9
S49
E
P
P
Q
P
P
I
S
W
R
V
R
G
G
G
Site 10
T60
R
G
G
G
P
A
E
T
T
W
L
G
E
G
G
Site 11
T61
G
G
G
P
A
E
T
T
W
L
G
E
G
G
G
Site 12
Y72
E
G
G
G
G
D
G
Y
Y
P
S
G
G
A
W
Site 13
Y73
G
G
G
G
D
G
Y
Y
P
S
G
G
A
W
P
Site 14
S75
G
G
D
G
Y
Y
P
S
G
G
A
W
P
E
P
Site 15
S88
E
P
G
R
A
G
G
S
H
Q
E
Q
P
P
Y
Site 16
Y95
S
H
Q
E
Q
P
P
Y
P
S
Y
N
S
N
Y
Site 17
Y98
E
Q
P
P
Y
P
S
Y
N
S
N
Y
W
N
S
Site 18
Y102
Y
P
S
Y
N
S
N
Y
W
N
S
T
A
R
S
Site 19
S105
Y
N
S
N
Y
W
N
S
T
A
R
S
R
A
P
Site 20
T106
N
S
N
Y
W
N
S
T
A
R
S
R
A
P
Y
Site 21
S109
Y
W
N
S
T
A
R
S
R
A
P
Y
P
S
T
Site 22
Y113
T
A
R
S
R
A
P
Y
P
S
T
Y
P
V
R
Site 23
S115
R
S
R
A
P
Y
P
S
T
Y
P
V
R
P
E
Site 24
T116
S
R
A
P
Y
P
S
T
Y
P
V
R
P
E
L
Site 25
Y117
R
A
P
Y
P
S
T
Y
P
V
R
P
E
L
Q
Site 26
S127
R
P
E
L
Q
G
Q
S
L
N
S
Y
T
N
G
Site 27
S130
L
Q
G
Q
S
L
N
S
Y
T
N
G
A
Y
G
Site 28
Y131
Q
G
Q
S
L
N
S
Y
T
N
G
A
Y
G
P
Site 29
T139
T
N
G
A
Y
G
P
T
Y
P
P
G
P
G
A
Site 30
Y140
N
G
A
Y
G
P
T
Y
P
P
G
P
G
A
N
Site 31
T148
P
P
G
P
G
A
N
T
A
S
Y
S
G
A
Y
Site 32
S150
G
P
G
A
N
T
A
S
Y
S
G
A
Y
Y
A
Site 33
Y155
T
A
S
Y
S
G
A
Y
Y
A
P
G
Y
T
Q
Site 34
Y156
A
S
Y
S
G
A
Y
Y
A
P
G
Y
T
Q
T
Site 35
Y160
G
A
Y
Y
A
P
G
Y
T
Q
T
S
Y
S
T
Site 36
Y165
P
G
Y
T
Q
T
S
Y
S
T
E
V
P
S
T
Site 37
S166
G
Y
T
Q
T
S
Y
S
T
E
V
P
S
T
Y
Site 38
T167
Y
T
Q
T
S
Y
S
T
E
V
P
S
T
Y
R
Site 39
S171
S
Y
S
T
E
V
P
S
T
Y
R
S
S
G
N
Site 40
T172
Y
S
T
E
V
P
S
T
Y
R
S
S
G
N
S
Site 41
Y173
S
T
E
V
P
S
T
Y
R
S
S
G
N
S
P
Site 42
S175
E
V
P
S
T
Y
R
S
S
G
N
S
P
T
P
Site 43
S176
V
P
S
T
Y
R
S
S
G
N
S
P
T
P
V
Site 44
S179
T
Y
R
S
S
G
N
S
P
T
P
V
S
R
W
Site 45
T181
R
S
S
G
N
S
P
T
P
V
S
R
W
I
Y
Site 46
S184
G
N
S
P
T
P
V
S
R
W
I
Y
P
Q
Q
Site 47
T195
Y
P
Q
Q
D
C
Q
T
E
A
P
P
L
R
G
Site 48
Y207
L
R
G
Q
V
P
G
Y
P
P
S
Q
N
P
G
Site 49
S210
Q
V
P
G
Y
P
P
S
Q
N
P
G
M
T
L
Site 50
T216
P
S
Q
N
P
G
M
T
L
P
H
Y
P
Y
G
Site 51
Y220
P
G
M
T
L
P
H
Y
P
Y
G
D
G
N
R
Site 52
S228
P
Y
G
D
G
N
R
S
V
P
Q
S
G
P
T
Site 53
S232
G
N
R
S
V
P
Q
S
G
P
T
V
R
P
Q
Site 54
T235
S
V
P
Q
S
G
P
T
V
R
P
Q
E
D
A
Site 55
S245
P
Q
E
D
A
W
A
S
P
G
A
Y
G
M
G
Site 56
Y249
A
W
A
S
P
G
A
Y
G
M
G
G
R
Y
P
Site 57
Y255
A
Y
G
M
G
G
R
Y
P
W
P
S
S
A
P
Site 58
S259
G
G
R
Y
P
W
P
S
S
A
P
S
A
P
P
Site 59
S260
G
R
Y
P
W
P
S
S
A
P
S
A
P
P
G
Site 60
S263
P
W
P
S
S
A
P
S
A
P
P
G
N
L
Y
Site 61
Y270
S
A
P
P
G
N
L
Y
M
T
E
S
T
S
P
Site 62
T272
P
P
G
N
L
Y
M
T
E
S
T
S
P
W
P
Site 63
S274
G
N
L
Y
M
T
E
S
T
S
P
W
P
S
S
Site 64
S276
L
Y
M
T
E
S
T
S
P
W
P
S
S
G
S
Site 65
S280
E
S
T
S
P
W
P
S
S
G
S
P
Q
S
P
Site 66
S281
S
T
S
P
W
P
S
S
G
S
P
Q
S
P
P
Site 67
S283
S
P
W
P
S
S
G
S
P
Q
S
P
P
S
P
Site 68
S286
P
S
S
G
S
P
Q
S
P
P
S
P
P
V
Q
Site 69
S289
G
S
P
Q
S
P
P
S
P
P
V
Q
Q
P
K
Site 70
S298
P
V
Q
Q
P
K
D
S
S
Y
P
Y
S
Q
S
Site 71
S299
V
Q
Q
P
K
D
S
S
Y
P
Y
S
Q
S
D
Site 72
Y300
Q
Q
P
K
D
S
S
Y
P
Y
S
Q
S
D
Q
Site 73
Y302
P
K
D
S
S
Y
P
Y
S
Q
S
D
Q
S
M
Site 74
S303
K
D
S
S
Y
P
Y
S
Q
S
D
Q
S
M
N
Site 75
S305
S
S
Y
P
Y
S
Q
S
D
Q
S
M
N
R
H
Site 76
Y321
F
P
C
S
V
H
Q
Y
E
S
S
G
T
V
N
Site 77
T326
H
Q
Y
E
S
S
G
T
V
N
N
D
D
S
D
Site 78
S332
G
T
V
N
N
D
D
S
D
L
L
D
S
Q
V
Site 79
S337
D
D
S
D
L
L
D
S
Q
V
Q
Y
S
A
E
Site 80
S342
L
D
S
Q
V
Q
Y
S
A
E
P
Q
L
Y
G
Site 81
Y348
Y
S
A
E
P
Q
L
Y
G
N
A
T
S
D
H
Site 82
S353
Q
L
Y
G
N
A
T
S
D
H
P
N
N
Q
D
Site 83
S363
P
N
N
Q
D
Q
S
S
S
L
P
E
E
C
V
Site 84
S364
N
N
Q
D
Q
S
S
S
L
P
E
E
C
V
P
Site 85
S372
L
P
E
E
C
V
P
S
D
E
S
T
P
P
S
Site 86
S375
E
C
V
P
S
D
E
S
T
P
P
S
I
K
K
Site 87
T376
C
V
P
S
D
E
S
T
P
P
S
I
K
K
I
Site 88
S379
S
D
E
S
T
P
P
S
I
K
K
I
I
H
V
Site 89
Y392
H
V
L
E
K
V
Q
Y
L
E
Q
E
V
E
E
Site 90
Y409
G
K
K
T
D
K
A
Y
W
L
L
E
E
M
L
Site 91
S425
K
E
L
L
E
L
D
S
V
E
T
G
G
Q
D
Site 92
S433
V
E
T
G
G
Q
D
S
V
R
Q
A
R
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation