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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMG1
Full Name:
Proteasome assembly chaperone 1
Alias:
C21LRP; C21-LRP; Chromosome 21 leucine-rich protein; Down syndrome critical region 2; Down syndrome critical region protein 2; Leucine-rich protein C21-LRP; LRPC21; PAC1; Proteasome (prosome, macropain) assembly chaperone 1; Proteasome assembling chaperone 1
Type:
Endoplasmic reticulum
Mass (Da):
32854
Number AA:
288
UniProt ID:
O95456
International Prot ID:
IPI00030770
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0043248
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
A
A
T
F
F
G
E
V
V
K
Site 2
T18
K
A
P
C
R
A
G
T
E
D
E
E
E
E
E
Site 3
T31
E
E
E
G
R
R
E
T
P
E
D
R
E
V
R
Site 4
T54
V
R
L
L
R
R
Q
T
K
T
S
L
E
V
S
Site 5
T56
L
L
R
R
Q
T
K
T
S
L
E
V
S
L
L
Site 6
S57
L
R
R
Q
T
K
T
S
L
E
V
S
L
L
E
Site 7
S61
T
K
T
S
L
E
V
S
L
L
E
K
Y
P
C
Site 8
T111
E
W
C
R
T
T
D
T
T
H
L
S
S
T
E
Site 9
T112
W
C
R
T
T
D
T
T
H
L
S
S
T
E
A
Site 10
Y124
T
E
A
F
C
V
F
Y
H
L
K
S
N
P
S
Site 11
Y147
Y
V
A
E
D
Q
Q
Y
Q
W
L
E
K
V
F
Site 12
T173
I
L
T
C
R
H
V
T
D
Y
K
T
S
E
S
Site 13
Y175
T
C
R
H
V
T
D
Y
K
T
S
E
S
T
G
Site 14
T177
R
H
V
T
D
Y
K
T
S
E
S
T
G
S
L
Site 15
S178
H
V
T
D
Y
K
T
S
E
S
T
G
S
L
P
Site 16
S180
T
D
Y
K
T
S
E
S
T
G
S
L
P
S
P
Site 17
S183
K
T
S
E
S
T
G
S
L
P
S
P
F
L
R
Site 18
S186
E
S
T
G
S
L
P
S
P
F
L
R
A
L
K
Site 19
T194
P
F
L
R
A
L
K
T
Q
N
F
K
D
S
A
Site 20
S200
K
T
Q
N
F
K
D
S
A
C
C
P
L
L
E
Site 21
S255
E
A
F
K
P
I
L
S
T
R
S
L
K
G
L
Site 22
T256
A
F
K
P
I
L
S
T
R
S
L
K
G
L
V
Site 23
S258
K
P
I
L
S
T
R
S
L
K
G
L
V
K
N
Site 24
S269
L
V
K
N
I
P
Q
S
T
E
I
L
K
K
L
Site 25
T278
E
I
L
K
K
L
M
T
T
N
E
I
Q
S
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation