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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VNN1
Full Name:
Pantetheinase
Alias:
Pantetheine hydrolase;Tiff66;Vascular non-inflammatory molecule 1
Type:
Mass (Da):
57012
Number AA:
513
UniProt ID:
O95497
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
S
R
A
S
C
Q
D
T
F
T
A
A
V
Y
E
Site 2
T26
A
S
C
Q
D
T
F
T
A
A
V
Y
E
H
A
Site 3
T42
I
L
P
N
A
T
L
T
P
V
S
R
E
E
A
Site 4
Y83
V
T
P
E
D
A
I
Y
G
W
N
F
N
R
D
Site 5
Y93
N
F
N
R
D
S
L
Y
P
Y
L
E
D
I
P
Site 6
Y95
N
R
D
S
L
Y
P
Y
L
E
D
I
P
D
P
Site 7
T118
N
R
N
R
F
G
Q
T
P
V
Q
E
R
L
S
Site 8
S125
T
P
V
Q
E
R
L
S
C
L
A
K
N
N
S
Site 9
Y134
L
A
K
N
N
S
I
Y
V
V
A
N
I
G
D
Site 10
T147
G
D
K
K
P
C
D
T
S
D
P
Q
C
P
P
Site 11
S148
D
K
K
P
C
D
T
S
D
P
Q
C
P
P
D
Site 12
Y158
Q
C
P
P
D
G
R
Y
Q
Y
N
T
D
V
V
Site 13
Y160
P
P
D
G
R
Y
Q
Y
N
T
D
V
V
F
D
Site 14
S168
N
T
D
V
V
F
D
S
Q
G
K
L
V
A
R
Site 15
Y176
Q
G
K
L
V
A
R
Y
H
K
Q
N
L
F
M
Site 16
T198
P
K
E
P
E
I
V
T
F
N
T
T
F
G
S
Site 17
Y269
F
L
A
S
N
I
H
Y
P
S
K
K
M
T
G
Site 18
S271
A
S
N
I
H
Y
P
S
K
K
M
T
G
S
G
Site 19
T275
H
Y
P
S
K
K
M
T
G
S
G
I
Y
A
P
Site 20
S277
P
S
K
K
M
T
G
S
G
I
Y
A
P
N
S
Site 21
Y280
K
M
T
G
S
G
I
Y
A
P
N
S
S
R
A
Site 22
S284
S
G
I
Y
A
P
N
S
S
R
A
F
H
Y
D
Site 23
T294
A
F
H
Y
D
M
K
T
E
E
G
K
L
L
L
Site 24
S302
E
E
G
K
L
L
L
S
Q
L
D
S
H
P
S
Site 25
S306
L
L
L
S
Q
L
D
S
H
P
S
H
S
A
V
Site 26
S309
S
Q
L
D
S
H
P
S
H
S
A
V
V
N
W
Site 27
S311
L
D
S
H
P
S
H
S
A
V
V
N
W
T
S
Site 28
S322
N
W
T
S
Y
A
S
S
I
E
A
L
S
S
G
Site 29
S327
A
S
S
I
E
A
L
S
S
G
N
K
E
F
K
Site 30
S328
S
S
I
E
A
L
S
S
G
N
K
E
F
K
G
Site 31
T336
G
N
K
E
F
K
G
T
V
F
F
D
E
F
T
Site 32
T388
G
A
F
D
G
L
H
T
V
E
G
R
Y
Y
L
Site 33
S419
G
D
S
A
E
T
A
S
T
R
F
E
M
F
S
Site 34
T420
D
S
A
E
T
A
S
T
R
F
E
M
F
S
L
Site 35
S426
S
T
R
F
E
M
F
S
L
S
G
T
F
G
T
Site 36
S428
R
F
E
M
F
S
L
S
G
T
F
G
T
Q
Y
Site 37
S455
A
P
G
E
F
Q
V
S
T
D
G
R
L
F
S
Site 38
T456
P
G
E
F
Q
V
S
T
D
G
R
L
F
S
L
Site 39
S462
S
T
D
G
R
L
F
S
L
K
P
T
S
G
P
Site 40
Y480
V
T
L
F
G
R
L
Y
E
K
D
W
A
S
N
Site 41
S486
L
Y
E
K
D
W
A
S
N
A
S
S
G
L
T
Site 42
S490
D
W
A
S
N
A
S
S
G
L
T
A
Q
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation