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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CBX6
Full Name:
Chromobox protein homolog 6
Alias:
Chromobox 6
Type:
Uncharacterized protein
Mass (Da):
43898
Number AA:
412
UniProt ID:
O95503
International Prot ID:
IPI00294926
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003682
PhosphoSite+
KinaseNET
Biological Process:
GO:0006333
GO:0016568
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
I
R
K
G
R
I
E
Y
L
V
K
W
K
G
W
Site 2
Y39
V
K
G
W
A
I
K
Y
S
T
W
E
P
E
E
Site 3
T41
G
W
A
I
K
Y
S
T
W
E
P
E
E
N
I
Site 4
Y67
K
E
R
E
R
E
L
Y
G
P
K
K
R
G
P
Site 5
T78
K
R
G
P
K
P
K
T
F
L
L
K
A
R
A
Site 6
S93
Q
A
E
A
L
R
I
S
D
V
H
F
S
V
K
Site 7
S98
R
I
S
D
V
H
F
S
V
K
P
S
A
S
A
Site 8
S102
V
H
F
S
V
K
P
S
A
S
A
S
S
P
K
Site 9
S104
F
S
V
K
P
S
A
S
A
S
S
P
K
L
H
Site 10
S106
V
K
P
S
A
S
A
S
S
P
K
L
H
S
S
Site 11
S107
K
P
S
A
S
A
S
S
P
K
L
H
S
S
A
Site 12
S112
A
S
S
P
K
L
H
S
S
A
A
V
H
R
L
Site 13
S113
S
S
P
K
L
H
S
S
A
A
V
H
R
L
K
Site 14
S130
I
R
R
C
H
R
M
S
R
R
P
L
P
R
P
Site 15
S143
R
P
D
P
Q
G
G
S
P
G
L
R
P
P
I
Site 16
S151
P
G
L
R
P
P
I
S
P
F
S
E
T
V
R
Site 17
S154
R
P
P
I
S
P
F
S
E
T
V
R
I
I
N
Site 18
T156
P
I
S
P
F
S
E
T
V
R
I
I
N
R
K
Site 19
S204
L
A
R
P
K
V
P
S
R
N
R
V
I
G
K
Site 20
S212
R
N
R
V
I
G
K
S
K
K
F
S
E
S
V
Site 21
S216
I
G
K
S
K
K
F
S
E
S
V
L
R
T
Q
Site 22
S218
K
S
K
K
F
S
E
S
V
L
R
T
Q
I
R
Site 23
T222
F
S
E
S
V
L
R
T
Q
I
R
H
M
K
F
Site 24
S246
P
A
P
L
V
A
P
S
P
G
K
A
E
A
S
Site 25
S253
S
P
G
K
A
E
A
S
A
P
G
P
G
L
L
Site 26
Y268
L
A
A
P
A
A
P
Y
D
A
R
S
S
G
S
Site 27
S272
A
A
P
Y
D
A
R
S
S
G
S
S
G
C
P
Site 28
S273
A
P
Y
D
A
R
S
S
G
S
S
G
C
P
S
Site 29
S276
D
A
R
S
S
G
S
S
G
C
P
S
P
T
P
Site 30
S280
S
G
S
S
G
C
P
S
P
T
P
Q
S
S
D
Site 31
T282
S
S
G
C
P
S
P
T
P
Q
S
S
D
P
D
Site 32
S285
C
P
S
P
T
P
Q
S
S
D
P
D
D
T
P
Site 33
S286
P
S
P
T
P
Q
S
S
D
P
D
D
T
P
P
Site 34
T291
Q
S
S
D
P
D
D
T
P
P
K
L
L
P
E
Site 35
T299
P
P
K
L
L
P
E
T
V
S
P
S
A
P
S
Site 36
S301
K
L
L
P
E
T
V
S
P
S
A
P
S
W
R
Site 37
S303
L
P
E
T
V
S
P
S
A
P
S
W
R
E
P
Site 38
S306
T
V
S
P
S
A
P
S
W
R
E
P
E
V
L
Site 39
S316
E
P
E
V
L
D
L
S
L
P
P
E
S
A
A
Site 40
S321
D
L
S
L
P
P
E
S
A
A
T
S
K
R
A
Site 41
T324
L
P
P
E
S
A
A
T
S
K
R
A
P
P
E
Site 42
S325
P
P
E
S
A
A
T
S
K
R
A
P
P
E
V
Site 43
S351
P
E
P
A
G
A
S
S
E
P
E
A
G
D
W
Site 44
S363
G
D
W
R
P
E
M
S
P
C
S
N
V
V
V
Site 45
S366
R
P
E
M
S
P
C
S
N
V
V
V
T
D
V
Site 46
S407
G
A
A
G
G
G
G
S
I
G
A
S
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation