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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRAMEF1
Full Name:
PRAME family member 1
Alias:
Type:
Mass (Da):
55162
Number AA:
474
UniProt ID:
O95521
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
R
D
Q
A
L
S
I
S
A
M
E
E
L
P
R
Site 2
S45
P
L
F
M
E
A
F
S
R
R
H
F
Q
T
L
Site 3
T51
F
S
R
R
H
F
Q
T
L
T
V
M
V
Q
A
Site 4
T53
R
R
H
F
Q
T
L
T
V
M
V
Q
A
W
P
Site 5
T72
P
L
G
S
L
M
K
T
L
H
L
E
T
L
K
Site 6
T90
E
G
L
H
M
L
L
T
Q
K
D
R
P
R
R
Site 7
S130
S
C
F
P
E
T
T
S
K
R
Q
T
A
E
D
Site 8
T134
E
T
T
S
K
R
Q
T
A
E
D
C
P
R
M
Site 9
Y166
P
Q
D
E
C
L
R
Y
L
F
Q
W
V
Y
Q
Site 10
Y172
R
Y
L
F
Q
W
V
Y
Q
R
R
G
L
V
H
Site 11
T190
S
K
L
V
N
Y
L
T
P
I
K
Y
L
R
K
Site 12
Y194
N
Y
L
T
P
I
K
Y
L
R
K
S
L
K
I
Site 13
S198
P
I
K
Y
L
R
K
S
L
K
I
I
Y
L
N
Site 14
Y203
R
K
S
L
K
I
I
Y
L
N
S
I
Q
E
L
Site 15
S216
E
L
E
I
R
N
M
S
W
P
R
L
I
R
K
Site 16
Y227
L
I
R
K
L
R
C
Y
L
K
E
M
K
N
L
Site 17
Y245
V
F
S
R
C
H
H
Y
T
S
D
N
E
L
Q
Site 18
T246
F
S
R
C
H
H
Y
T
S
D
N
E
L
Q
G
Site 19
S247
S
R
C
H
H
Y
T
S
D
N
E
L
Q
G
R
Site 20
S314
E
E
D
M
K
C
L
S
Q
Y
P
S
L
G
Y
Site 21
Y316
D
M
K
C
L
S
Q
Y
P
S
L
G
Y
L
K
Site 22
S318
K
C
L
S
Q
Y
P
S
L
G
Y
L
K
H
L
Site 23
T380
L
S
R
C
S
Q
L
T
T
F
Y
F
G
R
N
Site 24
T381
S
R
C
S
Q
L
T
T
F
Y
F
G
R
N
C
Site 25
Y383
C
S
Q
L
T
T
F
Y
F
G
R
N
C
M
S
Site 26
T401
L
K
D
L
L
R
H
T
S
G
L
S
K
L
S
Site 27
S402
K
D
L
L
R
H
T
S
G
L
S
K
L
S
L
Site 28
S405
L
R
H
T
S
G
L
S
K
L
S
L
E
T
Y
Site 29
S408
T
S
G
L
S
K
L
S
L
E
T
Y
P
A
P
Site 30
Y412
S
K
L
S
L
E
T
Y
P
A
P
E
E
S
L
Site 31
S418
T
Y
P
A
P
E
E
S
L
N
S
L
V
R
V
Site 32
S421
A
P
E
E
S
L
N
S
L
V
R
V
N
W
E
Site 33
T431
R
V
N
W
E
I
F
T
P
L
R
A
E
L
M
Site 34
T440
L
R
A
E
L
M
C
T
L
R
E
V
R
Q
P
Site 35
T455
K
R
I
F
I
G
P
T
P
C
P
S
C
G
S
Site 36
S459
I
G
P
T
P
C
P
S
C
G
S
S
P
S
E
Site 37
S463
P
C
P
S
C
G
S
S
P
S
E
E
L
E
L
Site 38
S465
P
S
C
G
S
S
P
S
E
E
L
E
L
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation