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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NADK
Full Name:
NAD kinase
Alias:
EC 2.7.1.23; FLJ13052; FLJ37724
Type:
Kinase (non-protein), metabolism of cofactors and vitamins group
Mass (Da):
49228
Number AA:
446
UniProt ID:
O95544
International Prot ID:
IPI00794844
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003951
GO:0046872
PhosphoSite+
KinaseNET
Biological Process:
GO:0046034
GO:0019674
GO:0016310
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
M
T
M
N
K
E
L
S
P
D
A
A
A
Y
C
Site 2
Y34
H
G
D
E
T
W
S
Y
N
H
P
I
R
G
R
Site 3
S44
P
I
R
G
R
A
K
S
R
S
L
S
A
S
P
Site 4
S46
R
G
R
A
K
S
R
S
L
S
A
S
P
A
L
Site 5
S48
R
A
K
S
R
S
L
S
A
S
P
A
L
G
S
Site 6
S50
K
S
R
S
L
S
A
S
P
A
L
G
S
T
K
Site 7
S55
S
A
S
P
A
L
G
S
T
K
E
F
R
R
T
Site 8
T56
A
S
P
A
L
G
S
T
K
E
F
R
R
T
R
Site 9
T62
S
T
K
E
F
R
R
T
R
S
L
H
G
P
C
Site 10
S64
K
E
F
R
R
T
R
S
L
H
G
P
C
P
V
Site 11
T99
D
P
A
S
Q
R
L
T
W
N
K
S
P
K
S
Site 12
S103
Q
R
L
T
W
N
K
S
P
K
S
V
L
V
I
Site 13
S106
T
W
N
K
S
P
K
S
V
L
V
I
K
K
M
Site 14
S117
I
K
K
M
R
D
A
S
L
L
Q
P
F
K
E
Site 15
Y137
M
E
E
N
M
I
V
Y
V
E
K
K
V
L
E
Site 16
S153
P
A
I
A
S
D
E
S
F
G
A
V
K
K
K
Site 17
T163
A
V
K
K
K
F
C
T
F
R
E
D
Y
D
D
Site 18
Y168
F
C
T
F
R
E
D
Y
D
D
I
S
N
Q
I
Site 19
S216
L
G
F
L
T
P
F
S
F
E
N
F
Q
S
Q
Site 20
S222
F
S
F
E
N
F
Q
S
Q
V
T
Q
V
I
E
Site 21
T253
K
E
L
R
G
K
K
T
A
V
H
N
G
L
G
Site 22
S264
N
G
L
G
E
N
G
S
Q
A
A
G
L
D
M
Site 23
S293
V
V
I
D
R
G
P
S
S
Y
L
S
N
V
D
Site 24
S294
V
I
D
R
G
P
S
S
Y
L
S
N
V
D
V
Site 25
Y295
I
D
R
G
P
S
S
Y
L
S
N
V
D
V
Y
Site 26
S297
R
G
P
S
S
Y
L
S
N
V
D
V
Y
L
D
Site 27
S319
Q
G
D
G
V
I
V
S
T
P
T
G
S
T
A
Site 28
S371
V
E
L
K
I
M
L
S
P
E
A
R
N
T
A
Site 29
T377
L
S
P
E
A
R
N
T
A
W
V
S
F
D
G
Site 30
S381
A
R
N
T
A
W
V
S
F
D
G
R
K
R
Q
Site 31
S395
Q
E
I
R
H
G
D
S
I
S
I
T
T
S
C
Site 32
S397
I
R
H
G
D
S
I
S
I
T
T
S
C
Y
P
Site 33
T399
H
G
D
S
I
S
I
T
T
S
C
Y
P
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation