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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCNT
Full Name:
Pericentrin
Alias:
KEN; Kendrin; KIAA0402; PCN; PCNT2; PCNTB; PCTN2; Pericentrin (kendrin); Pericentrin B; Pericentrin-B; SCKL4; Seckel syndrome 4
Type:
Mass (Da):
378081
Number AA:
3336
UniProt ID:
O95613
International Prot ID:
IPI00479143
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0042384
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
A
H
F
R
Q
R
K
T
K
G
D
S
S
H
S
Site 2
S32
R
K
T
K
G
D
S
S
H
S
E
K
K
T
A
Site 3
S34
T
K
G
D
S
S
H
S
E
K
K
T
A
K
R
Site 4
T38
S
S
H
S
E
K
K
T
A
K
R
K
G
S
A
Site 5
S44
K
T
A
K
R
K
G
S
A
V
D
A
S
V
Q
Site 6
S49
K
G
S
A
V
D
A
S
V
Q
E
E
S
P
V
Site 7
S54
D
A
S
V
Q
E
E
S
P
V
T
K
E
D
S
Site 8
T57
V
Q
E
E
S
P
V
T
K
E
D
S
A
L
C
Site 9
S61
S
P
V
T
K
E
D
S
A
L
C
G
G
G
D
Site 10
S72
G
G
G
D
I
C
K
S
T
S
C
D
D
T
P
Site 11
T73
G
G
D
I
C
K
S
T
S
C
D
D
T
P
D
Site 12
T78
K
S
T
S
C
D
D
T
P
D
G
A
G
G
A
Site 13
T121
P
E
Q
C
G
M
F
T
V
S
D
H
P
P
E
Site 14
T134
P
E
Q
H
G
M
F
T
V
G
D
H
P
P
E
Site 15
T147
P
E
Q
R
G
M
F
T
V
S
D
H
P
P
E
Site 16
S149
Q
R
G
M
F
T
V
S
D
H
P
P
E
Q
H
Site 17
T160
P
E
Q
H
G
M
F
T
V
S
D
H
P
P
E
Site 18
S162
Q
H
G
M
F
T
V
S
D
H
P
P
E
Q
R
Site 19
S175
Q
R
G
M
F
T
I
S
D
H
Q
P
E
Q
R
Site 20
T186
P
E
Q
R
G
M
F
T
V
S
D
H
T
P
E
Site 21
S188
Q
R
G
M
F
T
V
S
D
H
T
P
E
Q
R
Site 22
T191
M
F
T
V
S
D
H
T
P
E
Q
R
G
I
F
Site 23
S201
Q
R
G
I
F
T
I
S
D
H
P
A
E
Q
R
Site 24
T224
Q
E
C
E
L
A
I
T
D
L
E
S
G
R
E
Site 25
S228
L
A
I
T
D
L
E
S
G
R
E
D
E
A
G
Site 26
S239
D
E
A
G
L
H
Q
S
Q
A
V
H
G
L
E
Site 27
S253
E
L
E
A
L
R
L
S
L
S
N
M
H
T
A
Site 28
S255
E
A
L
R
L
S
L
S
N
M
H
T
A
Q
L
Site 29
T259
L
S
L
S
N
M
H
T
A
Q
L
E
L
T
Q
Site 30
T278
K
E
K
E
T
A
L
T
E
L
R
E
M
L
N
Site 31
S286
E
L
R
E
M
L
N
S
R
R
A
Q
E
L
A
Site 32
S334
E
L
K
E
K
L
Q
S
E
M
E
K
N
A
Q
Site 33
S352
T
L
K
E
D
W
E
S
E
K
D
L
C
L
E
Site 34
S366
E
N
L
R
K
E
L
S
A
K
H
Q
S
E
M
Site 35
S410
R
A
L
R
N
L
E
S
H
H
Q
A
A
I
E
Site 36
S425
K
L
R
E
D
L
Q
S
E
H
G
R
C
L
E
Site 37
S455
E
L
E
N
L
Q
A
S
Y
E
D
L
K
A
Q
Site 38
S472
E
E
I
R
R
L
W
S
Q
L
D
S
A
R
T
Site 39
S476
R
L
W
S
Q
L
D
S
A
R
T
S
R
Q
E
Site 40
T479
S
Q
L
D
S
A
R
T
S
R
Q
E
L
S
E
Site 41
S480
Q
L
D
S
A
R
T
S
R
Q
E
L
S
E
L
Site 42
S485
R
T
S
R
Q
E
L
S
E
L
H
E
Q
L
L
Site 43
S496
E
Q
L
L
A
R
T
S
R
V
E
D
L
E
Q
Site 44
T510
Q
L
K
Q
R
E
K
T
Q
H
E
S
E
L
E
Site 45
Y522
E
L
E
Q
L
R
I
Y
F
E
K
K
L
R
D
Site 46
T533
K
L
R
D
A
E
K
T
Y
Q
E
D
L
T
L
Site 47
T539
K
T
Y
Q
E
D
L
T
L
L
Q
Q
R
L
Q
Site 48
S589
E
P
E
R
H
K
E
S
L
P
R
F
Q
A
E
Site 49
S600
F
Q
A
E
L
E
E
S
H
R
H
Q
L
E
A
Site 50
S610
H
Q
L
E
A
L
E
S
P
L
C
I
Q
H
E
Site 51
S644
L
E
P
S
E
G
H
S
Q
E
L
P
W
V
H
Site 52
T664
D
G
D
L
E
A
D
T
E
R
A
A
R
V
L
Site 53
S682
T
E
H
K
V
Q
L
S
L
L
Q
T
E
L
K
Site 54
T686
V
Q
L
S
L
L
Q
T
E
L
K
E
E
I
E
Site 55
Y703
K
I
E
N
R
N
L
Y
E
K
L
Q
H
E
T
Site 56
T750
Q
E
F
Q
R
K
E
T
D
W
K
V
M
K
E
Site 57
T768
R
E
A
E
E
K
L
T
L
M
L
L
E
L
R
Site 58
S780
E
L
R
E
K
A
E
S
E
K
Q
T
I
I
N
Site 59
T784
K
A
E
S
E
K
Q
T
I
I
N
K
F
E
L
Site 60
S813
Q
I
L
D
L
E
R
S
L
T
E
Q
Q
G
R
Site 61
T815
L
D
L
E
R
S
L
T
E
Q
Q
G
R
L
Q
Site 62
T829
Q
Q
L
E
Q
D
L
T
S
D
D
A
L
H
C
Site 63
S830
Q
L
E
Q
D
L
T
S
D
D
A
L
H
C
S
Site 64
S837
S
D
D
A
L
H
C
S
Q
C
G
R
E
P
P
Site 65
S914
R
H
Q
Q
Q
L
L
S
V
T
A
E
L
E
A
Site 66
S933
A
L
G
E
L
T
A
S
L
E
S
K
Q
G
A
Site 67
T962
A
D
L
G
A
L
E
T
R
H
L
S
S
L
D
Site 68
S966
A
L
E
T
R
H
L
S
S
L
D
S
L
E
S
Site 69
S967
L
E
T
R
H
L
S
S
L
D
S
L
E
S
C
Site 70
S970
R
H
L
S
S
L
D
S
L
E
S
C
Y
L
S
Site 71
S973
S
S
L
D
S
L
E
S
C
Y
L
S
E
F
Q
Site 72
Y975
L
D
S
L
E
S
C
Y
L
S
E
F
Q
T
I
Site 73
S977
S
L
E
S
C
Y
L
S
E
F
Q
T
I
R
E
Site 74
T981
C
Y
L
S
E
F
Q
T
I
R
E
E
H
R
Q
Site 75
S1006
E
Q
L
W
K
K
D
S
L
H
Q
T
I
L
T
Site 76
T1010
K
K
D
S
L
H
Q
T
I
L
T
Q
E
L
E
Site 77
S1029
K
H
E
G
E
L
Q
S
V
R
D
H
L
R
T
Site 78
T1036
S
V
R
D
H
L
R
T
E
A
S
T
E
L
A
Site 79
T1045
A
S
T
E
L
A
G
T
V
A
H
E
L
Q
G
Site 80
S1060
V
H
Q
G
E
F
G
S
E
K
K
T
A
L
H
Site 81
T1064
E
F
G
S
E
K
K
T
A
L
H
E
K
E
E
Site 82
T1072
A
L
H
E
K
E
E
T
L
R
L
Q
S
A
Q
Site 83
S1077
E
E
T
L
R
L
Q
S
A
Q
A
Q
P
F
H
Site 84
S1090
F
H
Q
E
E
K
E
S
L
S
L
Q
L
Q
K
Site 85
S1111
Q
L
K
D
Q
V
L
S
L
S
H
E
I
E
E
Site 86
S1113
K
D
Q
V
L
S
L
S
H
E
I
E
E
C
R
Site 87
S1121
H
E
I
E
E
C
R
S
E
L
E
V
L
Q
Q
Site 88
S1142
R
E
G
A
N
L
L
S
M
L
K
A
D
V
N
Site 89
S1151
L
K
A
D
V
N
L
S
H
S
E
R
G
A
L
Site 90
S1153
A
D
V
N
L
S
H
S
E
R
G
A
L
Q
D
Site 91
T1172
L
L
G
L
F
G
E
T
L
R
A
A
V
T
L
Site 92
T1178
E
T
L
R
A
A
V
T
L
R
S
R
I
G
E
Site 93
S1181
R
A
A
V
T
L
R
S
R
I
G
E
R
V
G
Site 94
T1209
T
A
P
A
L
E
E
T
W
S
D
V
A
L
P
Site 95
S1211
P
A
L
E
E
T
W
S
D
V
A
L
P
E
L
Site 96
T1221
A
L
P
E
L
D
R
T
L
S
E
C
A
E
M
Site 97
S1223
P
E
L
D
R
T
L
S
E
C
A
E
M
S
S
Site 98
S1230
S
E
C
A
E
M
S
S
V
A
E
I
S
S
H
Site 99
S1235
M
S
S
V
A
E
I
S
S
H
M
R
E
S
F
Site 100
S1236
S
S
V
A
E
I
S
S
H
M
R
E
S
F
L
Site 101
S1241
I
S
S
H
M
R
E
S
F
L
M
S
P
E
S
Site 102
S1245
M
R
E
S
F
L
M
S
P
E
S
V
R
E
C
Site 103
S1248
S
F
L
M
S
P
E
S
V
R
E
C
E
Q
P
Site 104
S1277
L
M
E
M
A
L
D
S
S
R
Q
L
E
E
A
Site 105
S1278
M
E
M
A
L
D
S
S
R
Q
L
E
E
A
R
Site 106
S1289
E
E
A
R
Q
I
H
S
R
F
E
K
E
F
S
Site 107
S1296
S
R
F
E
K
E
F
S
F
K
N
E
E
T
A
Site 108
T1333
L
A
L
E
L
H
K
T
Q
G
T
L
E
G
F
Site 109
S1357
V
L
A
G
K
E
D
S
E
H
R
L
V
L
E
Site 110
S1367
R
L
V
L
E
L
E
S
L
R
R
Q
L
Q
Q
Site 111
S1391
E
E
C
T
R
L
W
S
R
G
E
A
T
A
T
Site 112
T1398
S
R
G
E
A
T
A
T
D
A
E
A
R
E
A
Site 113
T1415
R
K
E
V
E
D
L
T
K
E
Q
S
E
T
R
Site 114
S1419
E
D
L
T
K
E
Q
S
E
T
R
K
Q
A
E
Site 115
S1430
K
Q
A
E
K
D
R
S
A
L
L
S
Q
M
K
Site 116
S1434
K
D
R
S
A
L
L
S
Q
M
K
I
L
E
S
Site 117
S1441
S
Q
M
K
I
L
E
S
E
L
E
E
Q
L
S
Site 118
S1448
S
E
L
E
E
Q
L
S
Q
H
R
G
C
A
K
Site 119
S1469
A
L
E
Q
Q
V
A
S
L
D
K
H
L
R
N
Site 120
S1520
Q
P
W
G
P
R
D
S
Q
Q
A
P
L
D
G
Site 121
S1630
G
R
C
P
E
P
P
S
G
S
P
P
E
G
P
Site 122
S1632
C
P
E
P
P
S
G
S
P
P
E
G
P
E
I
Site 123
T1644
P
E
I
Q
L
E
V
T
Q
R
A
L
L
R
R
Site 124
S1653
R
A
L
L
R
R
E
S
E
V
L
D
L
K
E
Site 125
S1671
K
M
K
G
D
L
E
S
K
N
E
E
I
L
H
Site 126
S1688
L
K
L
D
M
Q
N
S
Q
T
A
V
S
L
R
Site 127
S1693
Q
N
S
Q
T
A
V
S
L
R
E
L
E
E
E
Site 128
T1702
R
E
L
E
E
E
N
T
S
L
K
V
I
Y
T
Site 129
S1703
E
L
E
E
E
N
T
S
L
K
V
I
Y
T
R
Site 130
Y1708
N
T
S
L
K
V
I
Y
T
R
S
S
E
I
E
Site 131
S1711
L
K
V
I
Y
T
R
S
S
E
I
E
E
L
K
Site 132
S1712
K
V
I
Y
T
R
S
S
E
I
E
E
L
K
A
Site 133
T1720
E
I
E
E
L
K
A
T
I
E
N
L
Q
E
N
Site 134
S1754
E
K
L
Q
H
E
L
S
L
M
G
P
V
V
H
Site 135
S1764
G
P
V
V
H
E
V
S
D
S
Q
A
G
S
L
Site 136
S1766
V
V
H
E
V
S
D
S
Q
A
G
S
L
Q
S
Site 137
S1770
V
S
D
S
Q
A
G
S
L
Q
S
E
L
L
C
Site 138
S1773
S
Q
A
G
S
L
Q
S
E
L
L
C
S
Q
A
Site 139
S1778
L
Q
S
E
L
L
C
S
Q
A
G
G
P
R
G
Site 140
S1814
A
D
Q
E
R
R
H
S
Q
A
L
E
A
L
Q
Site 141
S1854
A
E
V
E
D
M
A
S
R
I
Q
E
F
E
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L
T
A
S
Q
D
P
E
H
Site 294
S3296
L
E
R
S
L
T
A
S
Q
D
P
E
H
S
L
Site 295
S3302
A
S
Q
D
P
E
H
S
L
T
E
Y
I
H
H
Site 296
T3304
Q
D
P
E
H
S
L
T
E
Y
I
H
H
L
E
Site 297
Y3306
P
E
H
S
L
T
E
Y
I
H
H
L
E
V
I
Site 298
S3324
L
G
G
V
L
P
D
S
T
S
K
K
S
C
H
Site 299
T3325
G
G
V
L
P
D
S
T
S
K
K
S
C
H
P
Site 300
S3326
G
V
L
P
D
S
T
S
K
K
S
C
H
P
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation