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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NTN1
Full Name:
Netrin-1
Alias:
NET1; netrin 1; netrin-1; NTN1L
Type:
Secreted protein
Mass (Da):
67734
Number AA:
604
UniProt ID:
O95631
International Prot ID:
IPI00006732
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
A
A
Q
P
D
P
C
S
D
E
N
G
H
P
R
Site 2
S67
F
G
K
D
V
R
V
S
S
T
C
G
R
P
P
Site 3
S68
G
K
D
V
R
V
S
S
T
C
G
R
P
P
A
Site 4
T69
K
D
V
R
V
S
S
T
C
G
R
P
P
A
R
Site 5
Y77
C
G
R
P
P
A
R
Y
C
V
V
S
E
R
G
Site 6
S81
P
A
R
Y
C
V
V
S
E
R
G
E
E
R
L
Site 7
S90
R
G
E
E
R
L
R
S
C
H
L
C
N
A
S
Site 8
S97
S
C
H
L
C
N
A
S
D
P
K
K
A
H
P
Site 9
T109
A
H
P
P
A
F
L
T
D
L
N
N
P
H
N
Site 10
Y146
G
K
K
F
E
V
T
Y
V
S
L
Q
F
C
S
Site 11
S148
K
F
E
V
T
Y
V
S
L
Q
F
C
S
P
R
Site 12
S153
Y
V
S
L
Q
F
C
S
P
R
P
E
S
M
A
Site 13
S158
F
C
S
P
R
P
E
S
M
A
I
Y
K
S
M
Site 14
Y162
R
P
E
S
M
A
I
Y
K
S
M
D
Y
G
R
Site 15
Y167
A
I
Y
K
S
M
D
Y
G
R
T
W
V
P
F
Site 16
Y185
S
T
Q
C
R
K
M
Y
N
R
P
H
R
A
P
Site 17
T204
N
E
Q
E
A
V
C
T
D
S
H
T
D
M
R
Site 18
S206
Q
E
A
V
C
T
D
S
H
T
D
M
R
P
L
Site 19
T208
A
V
C
T
D
S
H
T
D
M
R
P
L
S
G
Site 20
S221
S
G
G
L
I
A
F
S
T
L
D
G
R
P
S
Site 21
S228
S
T
L
D
G
R
P
S
A
H
D
F
D
N
S
Site 22
S235
S
A
H
D
F
D
N
S
P
V
L
Q
D
W
V
Site 23
T256
V
A
F
S
R
L
H
T
F
G
D
E
N
E
D
Site 24
S265
G
D
E
N
E
D
D
S
E
L
A
R
D
S
Y
Site 25
S271
D
S
E
L
A
R
D
S
Y
F
Y
A
V
S
D
Site 26
Y272
S
E
L
A
R
D
S
Y
F
Y
A
V
S
D
L
Site 27
S277
D
S
Y
F
Y
A
V
S
D
L
Q
V
G
G
R
Site 28
Y323
D
R
C
K
P
F
H
Y
D
R
P
W
Q
R
A
Site 29
T331
D
R
P
W
Q
R
A
T
A
R
E
A
N
E
C
Site 30
Y357
C
R
F
N
M
E
L
Y
K
L
S
G
R
K
S
Site 31
S360
N
M
E
L
Y
K
L
S
G
R
K
S
G
G
V
Site 32
S364
Y
K
L
S
G
R
K
S
G
G
V
C
L
N
C
Site 33
Y387
C
H
Y
C
K
E
G
Y
Y
R
D
M
G
K
P
Site 34
Y388
H
Y
C
K
E
G
Y
Y
R
D
M
G
K
P
I
Site 35
T396
R
D
M
G
K
P
I
T
H
R
K
A
C
K
A
Site 36
T415
P
V
G
A
A
G
K
T
C
N
Q
T
T
G
Q
Site 37
Y441
C
N
R
C
A
K
G
Y
Q
Q
S
R
S
P
I
Site 38
S444
C
A
K
G
Y
Q
Q
S
R
S
P
I
A
P
C
Site 39
S446
K
G
Y
Q
Q
S
R
S
P
I
A
P
C
I
K
Site 40
S464
A
P
P
T
T
A
A
S
S
V
E
E
P
E
D
Site 41
S465
P
P
T
T
A
A
S
S
V
E
E
P
E
D
C
Site 42
S474
E
E
P
E
D
C
D
S
Y
C
K
A
S
K
G
Site 43
Y475
E
P
E
D
C
D
S
Y
C
K
A
S
K
G
K
Site 44
Y490
L
K
I
N
M
K
K
Y
C
K
K
D
Y
A
V
Site 45
Y495
K
K
Y
C
K
K
D
Y
A
V
Q
I
H
I
L
Site 46
S519
K
F
T
V
N
I
I
S
V
Y
K
Q
G
T
S
Site 47
S526
S
V
Y
K
Q
G
T
S
R
I
R
R
G
D
Q
Site 48
S534
R
I
R
R
G
D
Q
S
L
W
I
R
S
R
D
Site 49
Y555
K
I
K
P
L
K
K
Y
L
L
L
G
N
A
E
Site 50
S564
L
L
G
N
A
E
D
S
P
D
Q
S
G
I
V
Site 51
S568
A
E
D
S
P
D
Q
S
G
I
V
A
D
K
S
Site 52
S576
G
I
V
A
D
K
S
S
L
V
I
Q
W
R
D
Site 53
T584
L
V
I
Q
W
R
D
T
W
A
R
R
L
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation