PhosphoNET

           
Protein Info 
   
Short Name:  CPSF4
Full Name:  Cleavage and polyadenylation specificity factor subunit 4
Alias:  Cleavage and polyadenylation specific factor 4, 30kDa; Cleavage and polyadenylation specificity factor 30 kDa; Cleavage and polyadenylation specificity factor 30 kDa subunit; Cleavage and polyadenylation specificity factor 4; Cleavage-polyadenylation specificity factor; Cleavage-polyadenylation specificity factor, 30kD; CPSF 30 kDa; CPSF30; NAR; NEB1; Neb-1; No arches; No arches-like zinc finger protein; NS1 effector domain-binding 1
Type: 
Mass (Da):  30255
Number AA:  269
UniProt ID:  O95639
International Prot ID:  IPI00009137
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0008270  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0044419  GO:0006397  GO:0006397 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MQEIIASVDHIKFD
Site 2S61MCPFRHISGEKTVVC
Site 3Y88QCEFLHEYDMTKMPE
Site 4Y97MTKMPECYFYSKFGE
Site 5Y99KMPECYFYSKFGECS
Site 6S192TQPPAKQSNNPPLQR
Site 7S200NNPPLQRSSSLIQLT
Site 8S201NPPLQRSSSLIQLTS
Site 9S202PPLQRSSSLIQLTSQ
Site 10T207SSSLIQLTSQNSSPN
Site 11S208SSLIQLTSQNSSPNQ
Site 12S211IQLTSQNSSPNQQRT
Site 13S212QLTSQNSSPNQQRTP
Site 14T218SSPNQQRTPQVIGVM
Site 15S227QVIGVMQSQNSSAGN
Site 16S231VMQSQNSSAGNRGPR
Site 17Y246PLEQVTCYKCGEKGH
Site 18Y254KCGEKGHYANRCTKG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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