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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDS2
Full Name:
Phosphatidate cytidylyltransferase 2
Alias:
CDP-DAG synthase 2; CDP-DG synthetase 2; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2; CDP-diacylglycerol synthase 2; CDP-diglyceride pyrophosphorylase 2; CDP-diglyceride synthetase 2; CDS 2; CTP:phosphatidate cytidylyltransferase 2; CTP;phosphatidate cytidylyltransferase 2
Type:
Lipid Metabolism - glycerophospholipid; Transferase; Endoplasmic reticulum; EC 2.7.7.41
Mass (Da):
51418
Number AA:
445
UniProt ID:
O95674
International Prot ID:
IPI00032150
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0004605
PhosphoSite+
KinaseNET
Biological Process:
GO:0008654
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
A
P
P
E
D
K
E
S
E
S
E
A
K
V
D
Site 2
S23
P
E
D
K
E
S
E
S
E
A
K
V
D
G
E
Site 3
T31
E
A
K
V
D
G
E
T
A
S
D
S
E
S
R
Site 4
S33
K
V
D
G
E
T
A
S
D
S
E
S
R
A
E
Site 5
S35
D
G
E
T
A
S
D
S
E
S
R
A
E
S
A
Site 6
S37
E
T
A
S
D
S
E
S
R
A
E
S
A
P
L
Site 7
S41
D
S
E
S
R
A
E
S
A
P
L
P
V
S
A
Site 8
S47
E
S
A
P
L
P
V
S
A
D
D
T
P
E
V
Site 9
T51
L
P
V
S
A
D
D
T
P
E
V
L
N
R
A
Site 10
S60
E
V
L
N
R
A
L
S
N
L
S
S
R
W
K
Site 11
Y114
H
E
I
I
T
I
G
Y
N
V
Y
H
S
Y
D
Site 12
Y117
I
T
I
G
Y
N
V
Y
H
S
Y
D
L
P
W
Site 13
Y120
G
Y
N
V
Y
H
S
Y
D
L
P
W
F
R
T
Site 14
Y148
Y
G
E
T
V
T
D
Y
F
F
T
L
V
Q
R
Site 15
S163
E
E
P
L
R
I
L
S
K
Y
H
R
F
I
S
Site 16
Y165
P
L
R
I
L
S
K
Y
H
R
F
I
S
F
T
Site 17
Y190
L
S
L
V
K
K
H
Y
R
L
Q
F
Y
M
F
Site 18
S255
R
T
P
L
I
K
L
S
P
K
K
T
W
E
G
Site 19
T259
I
K
L
S
P
K
K
T
W
E
G
F
I
G
G
Site 20
T297
P
V
E
Y
N
N
D
T
N
S
F
T
V
D
C
Site 21
T301
N
N
D
T
N
S
F
T
V
D
C
E
P
S
D
Site 22
S307
F
T
V
D
C
E
P
S
D
L
F
R
L
Q
E
Site 23
Y315
D
L
F
R
L
Q
E
Y
N
I
P
G
V
I
Q
Site 24
S407
F
I
R
G
P
N
P
S
K
L
I
Q
Q
F
L
Site 25
T415
K
L
I
Q
Q
F
L
T
L
R
P
D
Q
Q
L
Site 26
T427
Q
Q
L
H
I
F
N
T
L
R
S
H
L
I
D
Site 27
T439
L
I
D
K
G
M
L
T
S
T
T
E
D
E
_
Site 28
S440
I
D
K
G
M
L
T
S
T
T
E
D
E
_
_
Site 29
T441
D
K
G
M
L
T
S
T
T
E
D
E
_
_
_
Site 30
T442
K
G
M
L
T
S
T
T
E
D
E
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation