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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ESRRB
Full Name:
Steroid hormone receptor ERR2
Alias:
ERR beta-2; ERR2; ERRb; ERRB2; ERRbeta; ERR-beta; ERRbeta-2; ESRL2; Estrogen receptor-like 2; Estrogen-related receptor, beta; NR3B2
Type:
Nucleus protein
Mass (Da):
55619
Number AA:
500
UniProt ID:
O95718
International Prot ID:
IPI00032812
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0005496
GO:0003707
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
S
D
D
R
H
L
G
S
S
C
G
S
F
I
K
Site 2
S11
D
D
R
H
L
G
S
S
C
G
S
F
I
K
T
Site 3
S14
H
L
G
S
S
C
G
S
F
I
K
T
E
P
S
Site 4
T18
S
C
G
S
F
I
K
T
E
P
S
S
P
S
S
Site 5
S21
S
F
I
K
T
E
P
S
S
P
S
S
G
I
D
Site 6
S22
F
I
K
T
E
P
S
S
P
S
S
G
I
D
A
Site 7
S25
T
E
P
S
S
P
S
S
G
I
D
A
L
S
H
Site 8
S31
S
S
G
I
D
A
L
S
H
H
S
P
S
G
S
Site 9
S34
I
D
A
L
S
H
H
S
P
S
G
S
S
D
A
Site 10
S36
A
L
S
H
H
S
P
S
G
S
S
D
A
S
G
Site 11
S38
S
H
H
S
P
S
G
S
S
D
A
S
G
G
F
Site 12
S39
H
H
S
P
S
G
S
S
D
A
S
G
G
F
G
Site 13
S58
T
H
A
N
G
L
D
S
P
P
M
F
A
G
A
Site 14
T70
A
G
A
G
L
G
G
T
P
C
R
K
S
Y
E
Site 15
S75
G
G
T
P
C
R
K
S
Y
E
D
C
A
S
G
Site 16
Y76
G
T
P
C
R
K
S
Y
E
D
C
A
S
G
I
Site 17
S81
K
S
Y
E
D
C
A
S
G
I
M
E
D
S
A
Site 18
Y115
D
I
A
S
G
Y
H
Y
G
V
A
S
C
E
A
Site 19
Y137
T
I
Q
G
N
I
E
Y
S
C
P
A
T
N
E
Site 20
T142
I
E
Y
S
C
P
A
T
N
E
C
E
I
T
K
Site 21
T148
A
T
N
E
C
E
I
T
K
R
R
R
K
S
C
Site 22
Y185
V
R
G
G
R
Q
K
Y
K
R
R
L
D
S
E
Site 23
S191
K
Y
K
R
R
L
D
S
E
S
S
P
Y
L
S
Site 24
S193
K
R
R
L
D
S
E
S
S
P
Y
L
S
L
Q
Site 25
S194
R
R
L
D
S
E
S
S
P
Y
L
S
L
Q
I
Site 26
Y196
L
D
S
E
S
S
P
Y
L
S
L
Q
I
S
P
Site 27
S198
S
E
S
S
P
Y
L
S
L
Q
I
S
P
P
A
Site 28
S202
P
Y
L
S
L
Q
I
S
P
P
A
K
K
P
L
Site 29
Y225
V
A
E
P
D
K
L
Y
A
M
P
P
P
G
M
Site 30
S266
K
H
I
P
G
F
S
S
L
S
L
G
D
Q
M
Site 31
Y301
P
Y
D
D
K
L
V
Y
A
E
D
Y
I
M
D
Site 32
Y305
K
L
V
Y
A
E
D
Y
I
M
D
E
E
H
S
Site 33
Y331
I
L
Q
L
V
R
R
Y
K
K
L
K
V
E
K
Site 34
S352
K
A
L
A
L
A
N
S
D
S
M
Y
I
E
D
Site 35
S354
L
A
L
A
N
S
D
S
M
Y
I
E
D
L
E
Site 36
Y356
L
A
N
S
D
S
M
Y
I
E
D
L
E
A
V
Site 37
Y377
L
H
E
A
L
Q
D
Y
E
L
S
Q
R
H
E
Site 38
S380
A
L
Q
D
Y
E
L
S
Q
R
H
E
E
P
W
Site 39
T389
R
H
E
E
P
W
R
T
G
K
L
L
L
T
L
Site 40
T395
R
T
G
K
L
L
L
T
L
P
L
L
R
Q
T
Site 41
T402
T
L
P
L
L
R
Q
T
A
A
K
A
V
Q
H
Site 42
S439
K
A
W
A
R
A
D
S
L
Q
E
W
R
P
L
Site 43
S451
R
P
L
E
Q
V
P
S
P
L
H
R
A
T
K
Site 44
T457
P
S
P
L
H
R
A
T
K
R
Q
H
V
H
F
Site 45
T466
R
Q
H
V
H
F
L
T
P
L
P
P
P
P
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation