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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IL33
Full Name:
Interleukin-33
Alias:
Interleukin-1 family member 11;Nuclear factor from high endothelial venules
Type:
Mass (Da):
30759
Number AA:
270
UniProt ID:
O95760
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
K
P
K
M
K
Y
S
T
N
K
I
S
T
A
Site 2
T9
K
P
K
M
K
Y
S
T
N
K
I
S
T
A
K
Site 3
T20
S
T
A
K
W
K
N
T
A
S
K
A
L
C
F
Site 4
S32
L
C
F
K
L
G
K
S
Q
Q
K
A
K
E
V
Site 5
Y43
A
K
E
V
C
P
M
Y
F
M
K
L
R
S
G
Site 6
Y59
M
I
K
K
E
A
C
Y
F
R
R
E
T
T
K
Site 7
T64
A
C
Y
F
R
R
E
T
T
K
R
P
S
L
K
Site 8
T65
C
Y
F
R
R
E
T
T
K
R
P
S
L
K
T
Site 9
S69
R
E
T
T
K
R
P
S
L
K
T
G
R
K
H
Site 10
T72
T
K
R
P
S
L
K
T
G
R
K
H
K
R
H
Site 11
Y104
G
I
S
G
V
Q
K
Y
T
R
A
L
H
D
S
Site 12
S111
Y
T
R
A
L
H
D
S
S
I
T
G
I
S
P
Site 13
S112
T
R
A
L
H
D
S
S
I
T
G
I
S
P
I
Site 14
S125
P
I
T
E
Y
L
A
S
L
S
T
Y
N
D
Q
Site 15
S127
T
E
Y
L
A
S
L
S
T
Y
N
D
Q
S
I
Site 16
T128
E
Y
L
A
S
L
S
T
Y
N
D
Q
S
I
T
Site 17
Y129
Y
L
A
S
L
S
T
Y
N
D
Q
S
I
T
F
Site 18
S133
L
S
T
Y
N
D
Q
S
I
T
F
A
L
E
D
Site 19
T135
T
Y
N
D
Q
S
I
T
F
A
L
E
D
E
S
Site 20
S142
T
F
A
L
E
D
E
S
Y
E
I
Y
V
E
D
Site 21
Y143
F
A
L
E
D
E
S
Y
E
I
Y
V
E
D
L
Site 22
Y146
E
D
E
S
Y
E
I
Y
V
E
D
L
K
K
D
Site 23
S162
K
K
D
K
V
L
L
S
Y
Y
E
S
Q
H
P
Site 24
Y163
K
D
K
V
L
L
S
Y
Y
E
S
Q
H
P
S
Site 25
Y164
D
K
V
L
L
S
Y
Y
E
S
Q
H
P
S
N
Site 26
S166
V
L
L
S
Y
Y
E
S
Q
H
P
S
N
E
S
Site 27
S170
Y
Y
E
S
Q
H
P
S
N
E
S
G
D
G
V
Site 28
S173
S
Q
H
P
S
N
E
S
G
D
G
V
D
G
K
Site 29
T185
D
G
K
M
L
M
V
T
L
S
P
T
K
D
F
Site 30
S255
A
L
I
K
V
D
S
S
E
N
L
C
T
E
N
Site 31
T260
D
S
S
E
N
L
C
T
E
N
I
L
F
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation