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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR75
Full Name:
Probable G-protein coupled receptor 75
Alias:
Type:
Mass (Da):
59359
Number AA:
540
UniProt ID:
O95800
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
Q
D
A
P
N
A
T
S
L
H
V
P
H
S
Q
Site 2
S21
T
S
L
H
V
P
H
S
Q
E
G
N
S
T
S
Site 3
T27
H
S
Q
E
G
N
S
T
S
L
Q
E
G
L
Q
Site 4
S28
S
Q
E
G
N
S
T
S
L
Q
E
G
L
Q
D
Site 5
S157
K
Q
P
N
R
T
A
S
F
P
C
T
V
L
L
Site 6
S186
A
T
L
K
T
S
K
S
H
L
C
L
P
M
S
Site 7
T228
S
Y
I
M
I
A
Q
T
L
R
K
N
A
Q
V
Site 8
T243
R
K
C
P
P
V
I
T
V
D
A
S
R
P
Q
Site 9
Y272
Q
C
A
M
P
A
L
Y
R
N
Q
N
Y
N
K
Site 10
Y288
Q
H
V
Q
T
R
G
Y
T
K
S
P
N
Q
L
Site 11
T289
H
V
Q
T
R
G
Y
T
K
S
P
N
Q
L
V
Site 12
S291
Q
T
R
G
Y
T
K
S
P
N
Q
L
V
T
P
Site 13
T297
K
S
P
N
Q
L
V
T
P
A
A
S
R
L
Q
Site 14
Y376
S
G
L
N
P
F
I
Y
S
R
N
S
A
G
L
Site 15
S377
G
L
N
P
F
I
Y
S
R
N
S
A
G
L
R
Site 16
S380
P
F
I
Y
S
R
N
S
A
G
L
R
R
K
V
Site 17
S422
L
E
V
N
R
N
K
S
S
H
H
E
T
N
S
Site 18
T427
N
K
S
S
H
H
E
T
N
S
A
Y
M
L
S
Site 19
S429
S
S
H
H
E
T
N
S
A
Y
M
L
S
P
K
Site 20
S434
T
N
S
A
Y
M
L
S
P
K
P
Q
K
K
F
Site 21
S449
V
D
Q
A
C
G
P
S
H
S
K
E
S
M
V
Site 22
S451
Q
A
C
G
P
S
H
S
K
E
S
M
V
S
P
Site 23
S454
G
P
S
H
S
K
E
S
M
V
S
P
K
I
S
Site 24
S457
H
S
K
E
S
M
V
S
P
K
I
S
A
G
H
Site 25
S461
S
M
V
S
P
K
I
S
A
G
H
Q
H
C
G
Site 26
S472
Q
H
C
G
Q
S
S
S
T
P
I
N
T
R
I
Site 27
T473
H
C
G
Q
S
S
S
T
P
I
N
T
R
I
E
Site 28
Y482
I
N
T
R
I
E
P
Y
Y
S
I
Y
N
S
S
Site 29
Y483
N
T
R
I
E
P
Y
Y
S
I
Y
N
S
S
P
Site 30
S484
T
R
I
E
P
Y
Y
S
I
Y
N
S
S
P
S
Site 31
Y486
I
E
P
Y
Y
S
I
Y
N
S
S
P
S
Q
E
Site 32
S488
P
Y
Y
S
I
Y
N
S
S
P
S
Q
E
E
S
Site 33
S489
Y
Y
S
I
Y
N
S
S
P
S
Q
E
E
S
S
Site 34
S491
S
I
Y
N
S
S
P
S
Q
E
E
S
S
P
C
Site 35
S495
S
S
P
S
Q
E
E
S
S
P
C
N
L
Q
P
Site 36
S496
S
P
S
Q
E
E
S
S
P
C
N
L
Q
P
V
Site 37
Y512
S
F
G
F
A
N
S
Y
I
A
M
H
Y
H
T
Site 38
Y527
T
N
D
L
V
Q
E
Y
D
S
T
S
A
K
Q
Site 39
S529
D
L
V
Q
E
Y
D
S
T
S
A
K
Q
I
P
Site 40
T530
L
V
Q
E
Y
D
S
T
S
A
K
Q
I
P
V
Site 41
S531
V
Q
E
Y
D
S
T
S
A
K
Q
I
P
V
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation