KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MLYCD
Full Name:
Malonyl-CoA decarboxylase, mitochondrial
Alias:
DCMC; malonyl-CoA decarboxylase; malonyl-CoA decarboxylase, mitochondrial; MCD
Type:
Carbohydrate Metabolism - propanoate; Lyase; Other Amino Acids Metabolism - beta-alanine; EC 4.1.1.9
Mass (Da):
55003
Number AA:
493
UniProt ID:
O95822
International Prot ID:
IPI00000663
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005777
Uniprot
OncoNet
Molecular Function:
GO:0050080
GO:0004492
PhosphoSite+
KinaseNET
Biological Process:
GO:0006637
GO:0006633
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
P
P
G
P
R
L
A
S
G
Q
A
A
G
A
L
Site 2
T51
L
R
R
A
V
P
P
T
P
A
Y
E
L
R
E
Site 3
Y54
A
V
P
P
T
P
A
Y
E
L
R
E
K
T
P
Site 4
T60
A
Y
E
L
R
E
K
T
P
A
P
A
E
G
Q
Site 5
Y131
Q
A
E
D
R
L
R
Y
A
L
V
P
R
Y
R
Site 6
Y137
R
Y
A
L
V
P
R
Y
R
G
L
F
H
H
I
Site 7
S145
R
G
L
F
H
H
I
S
K
L
D
G
G
V
R
Site 8
S192
M
L
S
E
W
F
S
S
G
F
L
N
L
E
R
Site 9
T201
F
L
N
L
E
R
V
T
W
H
S
P
C
E
V
Site 10
S204
L
E
R
V
T
W
H
S
P
C
E
V
L
Q
K
Site 11
Y234
M
K
R
R
V
G
P
Y
R
R
C
Y
F
F
S
Site 12
Y238
V
G
P
Y
R
R
C
Y
F
F
S
H
C
S
T
Site 13
S275
I
V
K
E
H
P
P
S
E
T
E
E
K
N
K
Site 14
S344
W
L
L
G
L
L
N
S
Q
T
K
E
H
G
R
Site 15
T346
L
G
L
L
N
S
Q
T
K
E
H
G
R
N
E
Site 16
T356
H
G
R
N
E
L
F
T
D
S
E
C
K
E
I
Site 17
S358
R
N
E
L
F
T
D
S
E
C
K
E
I
S
E
Site 18
S364
D
S
E
C
K
E
I
S
E
I
T
G
G
P
I
Site 19
S380
E
T
L
K
L
L
L
S
S
S
E
W
V
Q
S
Site 20
S382
L
K
L
L
L
S
S
S
E
W
V
Q
S
E
K
Site 21
S387
S
S
S
E
W
V
Q
S
E
K
L
V
R
A
L
Site 22
Y405
L
M
R
L
C
A
W
Y
L
Y
G
E
K
H
R
Site 23
Y407
R
L
C
A
W
Y
L
Y
G
E
K
H
R
G
Y
Site 24
Y414
Y
G
E
K
H
R
G
Y
A
L
N
P
V
A
N
Site 25
Y454
S
C
G
L
M
A
N
Y
R
Y
F
L
E
E
T
Site 26
Y456
G
L
M
A
N
Y
R
Y
F
L
E
E
T
G
P
Site 27
T461
Y
R
Y
F
L
E
E
T
G
P
N
S
T
S
Y
Site 28
S465
L
E
E
T
G
P
N
S
T
S
Y
L
G
S
K
Site 29
S467
E
T
G
P
N
S
T
S
Y
L
G
S
K
I
I
Site 30
Y468
T
G
P
N
S
T
S
Y
L
G
S
K
I
I
K
Site 31
S471
N
S
T
S
Y
L
G
S
K
I
I
K
A
S
E
Site 32
S482
K
A
S
E
Q
V
L
S
L
V
A
Q
F
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation