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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EML2
Full Name:
Echinoderm microtubule-associated protein-like 2
Alias:
Echinoderm microtubule associated protein like 2; Echinoderm MT-associated protein (EMAP)-like protein 70; ELP70; EMAL2; EMAP2; EMAP-2; EMAPL2; HuEMAP-2; Microtubule-associated protein like echinoderm EMAP
Type:
Microtubule, Cytoplasm, Microtubule associated complex protein
Mass (Da):
70679
Number AA:
649
UniProt ID:
O95834
International Prot ID:
IPI00015944
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0043231
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0007605
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
T
K
E
V
I
F
S
V
E
D
G
S
V
K
Site 2
S20
I
F
S
V
E
D
G
S
V
K
M
F
L
R
G
Site 3
T41
I
P
D
E
L
A
P
T
Y
S
L
D
T
R
S
Site 4
S43
D
E
L
A
P
T
Y
S
L
D
T
R
S
E
L
Site 5
T46
A
P
T
Y
S
L
D
T
R
S
E
L
P
S
C
Site 6
S48
T
Y
S
L
D
T
R
S
E
L
P
S
C
R
L
Site 7
S52
D
T
R
S
E
L
P
S
C
R
L
K
L
E
W
Site 8
Y61
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Site 9
Y73
R
D
C
R
A
N
L
Y
L
L
P
T
G
E
I
Site 10
S92
A
S
V
A
V
L
Y
S
V
E
E
Q
R
Q
R
Site 11
Y101
E
E
Q
R
Q
R
H
Y
L
G
H
N
D
D
I
Site 12
S144
P
H
V
R
I
W
D
S
V
S
L
S
T
L
H
Site 13
T212
N
E
A
V
L
V
A
T
F
H
P
T
D
P
T
Site 14
Y230
T
C
G
K
S
H
I
Y
F
W
T
L
E
G
G
Site 15
T233
K
S
H
I
Y
F
W
T
L
E
G
G
S
L
S
Site 16
S238
F
W
T
L
E
G
G
S
L
S
K
R
Q
G
L
Site 17
S240
T
L
E
G
G
S
L
S
K
R
Q
G
L
F
E
Site 18
Y254
E
K
H
E
K
P
K
Y
V
L
C
V
T
F
L
Site 19
T268
L
E
G
G
D
V
V
T
G
D
S
G
G
N
L
Site 20
Y276
G
D
S
G
G
N
L
Y
V
W
G
K
G
G
N
Site 21
T286
G
K
G
G
N
R
I
T
Q
A
V
L
G
A
H
Site 22
S310
L
R
D
G
T
L
V
S
G
G
G
R
D
R
R
Site 23
S323
R
R
V
V
L
W
G
S
D
Y
S
K
L
Q
E
Site 24
Y325
V
V
L
W
G
S
D
Y
S
K
L
Q
E
V
E
Site 25
S326
V
L
W
G
S
D
Y
S
K
L
Q
E
V
E
V
Site 26
T342
E
D
F
G
P
V
R
T
V
A
E
G
H
G
D
Site 27
T350
V
A
E
G
H
G
D
T
L
Y
V
G
T
T
R
Site 28
Y352
E
G
H
G
D
T
L
Y
V
G
T
T
R
N
S
Site 29
T355
G
D
T
L
Y
V
G
T
T
R
N
S
I
L
Q
Site 30
S359
Y
V
G
T
T
R
N
S
I
L
Q
G
S
V
H
Site 31
T385
E
E
L
W
G
L
A
T
H
P
S
R
A
Q
F
Site 32
T394
P
S
R
A
Q
F
V
T
C
G
Q
D
K
L
V
Site 33
S405
D
K
L
V
H
L
W
S
S
D
S
H
Q
P
L
Site 34
S406
K
L
V
H
L
W
S
S
D
S
H
Q
P
L
W
Site 35
S408
V
H
L
W
S
S
D
S
H
Q
P
L
W
S
R
Site 36
S423
I
I
E
D
P
A
R
S
A
G
F
H
P
S
G
Site 37
S429
R
S
A
G
F
H
P
S
G
S
V
L
A
V
G
Site 38
T447
G
R
W
L
L
L
D
T
E
T
H
D
L
V
A
Site 39
S464
T
D
G
N
E
Q
I
S
V
V
S
F
S
P
D
Site 40
S467
N
E
Q
I
S
V
V
S
F
S
P
D
G
A
Y
Site 41
Y474
S
F
S
P
D
G
A
Y
L
A
V
G
S
H
D
Site 42
Y485
G
S
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
Site 43
Y487
H
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
Site 44
T488
D
N
L
V
Y
V
Y
T
V
D
Q
G
G
R
K
Site 45
S497
D
Q
G
G
R
K
V
S
R
L
G
K
C
S
G
Site 46
S503
V
S
R
L
G
K
C
S
G
H
S
S
F
I
T
Site 47
T510
S
G
H
S
S
F
I
T
H
L
D
W
A
Q
D
Site 48
T523
Q
D
S
S
C
F
V
T
N
S
G
D
Y
E
I
Site 49
S525
S
S
C
F
V
T
N
S
G
D
Y
E
I
L
Y
Site 50
Y528
F
V
T
N
S
G
D
Y
E
I
L
Y
W
D
P
Site 51
Y532
S
G
D
Y
E
I
L
Y
W
D
P
A
T
C
K
Site 52
S590
H
D
G
K
L
L
A
S
A
D
D
F
G
K
V
Site 53
Y602
G
K
V
H
L
F
S
Y
P
C
C
Q
P
R
A
Site 54
Y614
P
R
A
L
S
H
K
Y
G
G
H
S
S
H
V
Site 55
T622
G
G
H
S
S
H
V
T
N
V
A
F
L
W
D
Site 56
T635
W
D
D
S
M
A
L
T
T
G
G
K
D
T
S
Site 57
S642
T
T
G
G
K
D
T
S
V
L
Q
W
R
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation