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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANGPTL1
Full Name:
Angiopoietin-related protein 1
Alias:
Angiopoietin-3;Angiopoietin-like protein 1
Type:
Mass (Da):
56720
Number AA:
491
UniProt ID:
O95841
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y36
K
K
I
N
Q
R
R
Y
P
R
A
T
D
G
K
Site 2
T40
Q
R
R
Y
P
R
A
T
D
G
K
E
E
A
K
Site 3
T52
E
A
K
K
C
A
Y
T
F
L
V
P
E
Q
R
Site 4
T61
L
V
P
E
Q
R
I
T
G
P
I
C
V
N
T
Site 5
S74
N
T
K
G
Q
D
A
S
T
I
K
D
M
I
T
Site 6
T81
S
T
I
K
D
M
I
T
R
M
D
L
E
N
L
Site 7
S93
E
N
L
K
D
V
L
S
R
Q
K
R
E
I
D
Site 8
S123
V
K
L
L
R
K
E
S
R
N
M
N
S
R
V
Site 9
T131
R
N
M
N
S
R
V
T
Q
L
Y
M
Q
L
L
Site 10
Y134
N
S
R
V
T
Q
L
Y
M
Q
L
L
H
E
I
Site 11
S148
I
I
R
K
R
D
N
S
L
E
L
S
Q
L
E
Site 12
S152
R
D
N
S
L
E
L
S
Q
L
E
N
K
I
L
Site 13
S205
E
Q
C
L
R
I
F
S
R
Q
D
T
H
V
S
Site 14
T209
R
I
F
S
R
Q
D
T
H
V
S
P
P
L
V
Site 15
S212
S
R
Q
D
T
H
V
S
P
P
L
V
Q
V
V
Site 16
S226
V
P
Q
H
I
P
N
S
Q
Q
Y
T
P
G
L
Site 17
Y229
H
I
P
N
S
Q
Q
Y
T
P
G
L
L
G
G
Site 18
T230
I
P
N
S
Q
Q
Y
T
P
G
L
L
G
G
N
Site 19
Y245
E
I
Q
R
D
P
G
Y
P
R
D
L
M
P
P
Site 20
T257
M
P
P
P
D
L
A
T
S
P
T
K
S
P
F
Site 21
S258
P
P
P
D
L
A
T
S
P
T
K
S
P
F
K
Site 22
T260
P
D
L
A
T
S
P
T
K
S
P
F
K
I
P
Site 23
S262
L
A
T
S
P
T
K
S
P
F
K
I
P
P
V
Site 24
S289
Q
A
K
E
A
G
H
S
V
S
G
I
Y
M
I
Site 25
S291
K
E
A
G
H
S
V
S
G
I
Y
M
I
K
P
Site 26
Y294
G
H
S
V
S
G
I
Y
M
I
K
P
E
N
S
Site 27
T319
S
L
D
P
G
G
W
T
V
I
Q
K
R
T
D
Site 28
Y338
F
F
R
N
W
E
N
Y
K
K
G
F
G
N
I
Site 29
Y349
F
G
N
I
D
G
E
Y
W
L
G
L
E
N
I
Site 30
Y365
M
L
S
N
Q
D
N
Y
K
L
L
I
E
L
E
Site 31
S375
L
I
E
L
E
D
W
S
D
K
K
V
Y
A
E
Site 32
Y380
D
W
S
D
K
K
V
Y
A
E
Y
S
S
F
R
Site 33
Y383
D
K
K
V
Y
A
E
Y
S
S
F
R
L
E
P
Site 34
S384
K
K
V
Y
A
E
Y
S
S
F
R
L
E
P
E
Site 35
S385
K
V
Y
A
E
Y
S
S
F
R
L
E
P
E
S
Site 36
S392
S
F
R
L
E
P
E
S
E
F
Y
R
L
R
L
Site 37
Y395
L
E
P
E
S
E
F
Y
R
L
R
L
G
T
Y
Site 38
T401
F
Y
R
L
R
L
G
T
Y
Q
G
N
A
G
D
Site 39
Y402
Y
R
L
R
L
G
T
Y
Q
G
N
A
G
D
S
Site 40
Y428
L
D
R
D
K
D
M
Y
A
G
N
C
A
H
F
Site 41
Y455
S
N
L
N
G
V
W
Y
R
G
G
H
Y
R
S
Site 42
Y473
D
G
I
F
W
A
E
Y
R
G
G
S
Y
S
L
Site 43
S477
W
A
E
Y
R
G
G
S
Y
S
L
R
A
V
Q
Site 44
S479
E
Y
R
G
G
S
Y
S
L
R
A
V
Q
M
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation