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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC25A27
Full Name:
Mitochondrial uncoupling protein 4
Alias:
Mitochondrial uncoupling protein 4; UCP 4
Type:
Mitochondrial transport protein
Mass (Da):
36064
Number AA:
323
UniProt ID:
O95847
International Prot ID:
IPI00383871
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006091
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
E
E
R
L
L
P
L
T
Q
R
W
P
R
A
S
Site 2
S21
T
Q
R
W
P
R
A
S
K
F
L
L
S
G
C
Site 3
T43
A
T
F
P
L
D
L
T
K
T
R
L
Q
M
Q
Site 4
S65
L
G
D
G
A
R
E
S
A
P
Y
R
G
M
V
Site 5
Y68
G
A
R
E
S
A
P
Y
R
G
M
V
R
T
A
Site 6
T74
P
Y
R
G
M
V
R
T
A
L
G
I
I
E
E
Site 7
Y96
Q
G
V
T
P
A
I
Y
R
H
V
V
Y
S
G
Site 8
T108
Y
S
G
G
R
M
V
T
Y
E
H
L
R
E
V
Site 9
Y109
S
G
G
R
M
V
T
Y
E
H
L
R
E
V
V
Site 10
S120
R
E
V
V
F
G
K
S
E
D
E
H
Y
P
L
Site 11
Y125
G
K
S
E
D
E
H
Y
P
L
W
K
S
V
I
Site 12
T209
L
V
N
M
G
D
L
T
T
Y
D
T
V
K
H
Site 13
T210
V
N
M
G
D
L
T
T
Y
D
T
V
K
H
Y
Site 14
Y211
N
M
G
D
L
T
T
Y
D
T
V
K
H
Y
L
Site 15
Y217
T
Y
D
T
V
K
H
Y
L
V
L
N
T
P
L
Site 16
T222
K
H
Y
L
V
L
N
T
P
L
E
D
N
I
M
Site 17
Y270
K
Q
G
R
G
L
L
Y
K
S
S
T
D
C
L
Site 18
S272
G
R
G
L
L
Y
K
S
S
T
D
C
L
I
Q
Site 19
S273
R
G
L
L
Y
K
S
S
T
D
C
L
I
Q
A
Site 20
Y290
G
E
G
F
M
S
L
Y
K
G
F
L
P
S
W
Site 21
Y311
S
M
V
F
W
L
T
Y
E
K
I
R
E
M
S
Site 22
S318
Y
E
K
I
R
E
M
S
G
V
S
P
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation