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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C2orf86
Full Name:
WD repeat-containing protein C2orf86
Alias:
Type:
Mass (Da):
85084
Number AA:
746
UniProt ID:
O95876
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
R
E
F
C
W
D
A
Y
S
K
A
A
G
S
R
Site 2
S16
A
Y
S
K
A
A
G
S
R
A
S
S
P
L
P
Site 3
S19
K
A
A
G
S
R
A
S
S
P
L
P
R
Q
D
Site 4
S20
A
A
G
S
R
A
S
S
P
L
P
R
Q
D
R
Site 5
S29
L
P
R
Q
D
R
D
S
F
C
H
Q
M
S
F
Site 6
T49
H
L
W
S
L
K
N
T
L
H
I
A
D
R
D
Site 7
Y60
A
D
R
D
I
G
I
Y
Q
Y
Y
D
K
K
D
Site 8
Y62
R
D
I
G
I
Y
Q
Y
Y
D
K
K
D
P
P
Site 9
Y63
D
I
G
I
Y
Q
Y
Y
D
K
K
D
P
P
A
Site 10
T71
D
K
K
D
P
P
A
T
E
H
G
N
L
E
K
Site 11
Y88
K
L
A
E
S
R
D
Y
P
W
T
L
K
N
R
Site 12
T91
E
S
R
D
Y
P
W
T
L
K
N
R
R
P
E
Site 13
S103
R
P
E
K
L
R
D
S
L
K
E
L
E
E
L
Site 14
S114
L
E
E
L
M
Q
N
S
R
C
V
L
S
K
W
Site 15
Y125
L
S
K
W
K
N
K
Y
V
C
Q
L
L
F
G
Site 16
S196
F
T
K
K
M
E
S
S
D
V
N
K
R
L
E
Site 17
S206
N
K
R
L
E
K
L
S
A
L
D
Y
K
I
F
Site 18
Y210
E
K
L
S
A
L
D
Y
K
I
F
Y
Y
E
I
Site 19
Y215
L
D
Y
K
I
F
Y
Y
E
I
P
G
P
I
N
Site 20
T224
I
P
G
P
I
N
K
T
T
E
R
H
L
A
I
Site 21
T225
P
G
P
I
N
K
T
T
E
R
H
L
A
I
N
Site 22
S256
A
W
P
W
A
P
I
S
S
E
K
D
R
A
N
Site 23
S278
Q
G
R
L
E
V
L
S
S
V
R
T
E
W
D
Site 24
S279
G
R
L
E
V
L
S
S
V
R
T
E
W
D
P
Site 25
T282
E
V
L
S
S
V
R
T
E
W
D
P
L
D
V
Site 26
T293
P
L
D
V
R
F
G
T
K
Q
P
Y
Q
V
F
Site 27
Y297
R
F
G
T
K
Q
P
Y
Q
V
F
T
V
E
H
Site 28
T301
K
Q
P
Y
Q
V
F
T
V
E
H
S
V
S
V
Site 29
S305
Q
V
F
T
V
E
H
S
V
S
V
D
K
E
P
Site 30
S307
F
T
V
E
H
S
V
S
V
D
K
E
P
M
A
Site 31
Y319
P
M
A
D
S
C
I
Y
E
C
I
R
N
K
I
Site 32
S330
R
N
K
I
Q
C
V
S
V
T
R
I
P
L
K
Site 33
T332
K
I
Q
C
V
S
V
T
R
I
P
L
K
S
K
Site 34
S342
P
L
K
S
K
A
I
S
C
C
R
N
V
T
E
Site 35
Y364
E
D
S
S
L
I
L
Y
E
T
H
R
R
V
T
Site 36
T371
Y
E
T
H
R
R
V
T
L
L
A
Q
T
E
L
Site 37
T425
E
D
R
L
P
R
E
T
L
Q
F
S
K
L
F
Site 38
S436
S
K
L
F
D
A
S
S
S
L
V
Q
M
Q
W
Site 39
S450
W
I
A
P
Q
V
V
S
Q
K
G
E
G
S
D
Site 40
S456
V
S
Q
K
G
E
G
S
D
I
Y
D
L
L
F
Site 41
Y459
K
G
E
G
S
D
I
Y
D
L
L
F
L
R
F
Site 42
T537
H
L
L
R
Q
K
L
T
P
E
R
E
A
Q
L
Site 43
S547
R
E
A
Q
L
E
T
S
L
G
T
F
Y
A
P
Site 44
Y552
E
T
S
L
G
T
F
Y
A
P
T
R
P
L
L
Site 45
S561
P
T
R
P
L
L
D
S
T
I
L
E
Y
R
D
Site 46
Y573
Y
R
D
Q
I
S
K
Y
A
R
R
F
F
H
H
Site 47
Y584
F
F
H
H
L
L
R
Y
Q
R
F
E
K
A
F
Site 48
Y608
D
L
F
M
D
I
H
Y
L
A
L
D
K
G
E
Site 49
S627
E
V
A
R
K
R
A
S
D
I
D
A
E
S
I
Site 50
S658
N
E
A
F
I
G
L
S
L
A
P
Q
G
E
D
Site 51
S666
L
A
P
Q
G
E
D
S
F
P
D
N
L
P
P
Site 52
T677
N
L
P
P
S
C
P
T
H
R
H
I
L
Q
Q
Site 53
S690
Q
Q
R
I
L
N
G
S
S
N
R
Q
I
I
D
Site 54
S691
Q
R
I
L
N
G
S
S
N
R
Q
I
I
D
R
Site 55
T715
S
G
F
L
M
T
N
T
C
N
A
E
D
G
E
Site 56
S737
Q
E
I
R
D
G
G
S
L
K
M
I
H
F
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation