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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ECD
Full Name:
Protein SGT1
Alias:
Ecdysoneless; Ecdysoneless homolog (Drosophila); Ecdysoneless homologue; GCR2; HSGT1; Suppressor of GCR2
Type:
Transcription, coactivator/corepressor
Mass (Da):
72758
Number AA:
644
UniProt ID:
O95905
International Prot ID:
IPI00027034
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0006110
GO:0045449
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
T
M
E
D
T
V
E
Y
C
L
F
L
I
P
D
Site 2
S25
L
F
L
I
P
D
E
S
R
D
S
D
K
H
K
Site 3
S28
I
P
D
E
S
R
D
S
D
K
H
K
E
I
L
Site 4
Y38
H
K
E
I
L
Q
K
Y
I
E
R
I
I
T
R
Site 5
Y64
N
Q
P
F
N
L
K
Y
K
P
G
K
G
G
V
Site 6
Y93
E
D
E
W
F
I
V
Y
V
I
K
Q
I
T
K
Site 7
S154
I
I
P
A
P
R
K
S
G
A
E
S
W
L
P
Site 8
S158
P
R
K
S
G
A
E
S
W
L
P
T
T
P
P
Site 9
T162
G
A
E
S
W
L
P
T
T
P
P
T
I
P
Q
Site 10
T163
A
E
S
W
L
P
T
T
P
P
T
I
P
Q
A
Site 11
S186
E
K
I
L
A
S
E
S
I
R
A
A
V
N
R
Site 12
Y198
V
N
R
R
I
R
G
Y
P
E
K
I
Q
A
S
Site 13
S205
Y
P
E
K
I
Q
A
S
L
H
R
A
H
C
F
Site 14
T251
R
A
C
R
V
F
K
T
F
L
P
E
T
R
I
Site 15
S283
R
F
V
P
D
R
R
S
G
Y
R
L
P
P
P
Site 16
Y285
V
P
D
R
R
S
G
Y
R
L
P
P
P
S
D
Site 17
S291
G
Y
R
L
P
P
P
S
D
P
Q
Y
R
A
H
Site 18
Y295
P
P
P
S
D
P
Q
Y
R
A
H
E
L
G
M
Site 19
S316
E
I
L
C
S
K
C
S
P
H
F
S
D
C
K
Site 20
S320
S
K
C
S
P
H
F
S
D
C
K
K
S
L
V
Site 21
S325
H
F
S
D
C
K
K
S
L
V
T
A
S
P
L
Site 22
S335
T
A
S
P
L
W
A
S
F
L
E
S
L
K
K
Site 23
S339
L
W
A
S
F
L
E
S
L
K
K
N
D
Y
F
Site 24
Y345
E
S
L
K
K
N
D
Y
F
K
G
L
I
E
G
Site 25
Y366
R
L
E
M
A
E
N
Y
F
Q
L
S
V
D
W
Site 26
S370
A
E
N
Y
F
Q
L
S
V
D
W
P
E
S
S
Site 27
S376
L
S
V
D
W
P
E
S
S
L
A
M
S
P
G
Site 28
S377
S
V
D
W
P
E
S
S
L
A
M
S
P
G
E
Site 29
S381
P
E
S
S
L
A
M
S
P
G
E
E
I
L
T
Site 30
S419
D
D
Q
W
L
D
L
S
P
D
Q
L
D
Q
L
Site 31
S436
E
A
V
G
K
K
E
S
E
S
V
S
K
E
E
Site 32
S438
V
G
K
K
E
S
E
S
V
S
K
E
E
K
E
Site 33
S440
K
K
E
S
E
S
V
S
K
E
E
K
E
Q
N
Site 34
Y448
K
E
E
K
E
Q
N
Y
D
L
T
E
V
S
E
Site 35
T451
K
E
Q
N
Y
D
L
T
E
V
S
E
S
M
K
Site 36
S462
E
S
M
K
A
F
I
S
K
V
S
T
H
K
G
Site 37
T466
A
F
I
S
K
V
S
T
H
K
G
A
E
L
P
Site 38
S477
A
E
L
P
R
E
P
S
E
A
P
I
T
F
D
Site 39
T482
E
P
S
E
A
P
I
T
F
D
A
D
S
F
L
Site 40
S487
P
I
T
F
D
A
D
S
F
L
N
Y
F
D
K
Site 41
Y491
D
A
D
S
F
L
N
Y
F
D
K
I
L
G
P
Site 42
S503
L
G
P
R
P
N
E
S
D
S
D
D
L
D
D
Site 43
S505
P
R
P
N
E
S
D
S
D
D
L
D
D
E
D
Site 44
S518
E
D
F
E
C
L
D
S
D
D
D
L
D
F
E
Site 45
T526
D
D
D
L
D
F
E
T
H
E
P
G
E
E
A
Site 46
S534
H
E
P
G
E
E
A
S
L
K
G
T
L
D
N
Site 47
T538
E
E
A
S
L
K
G
T
L
D
N
L
K
S
Y
Site 48
T556
M
D
Q
E
L
A
H
T
C
I
S
K
S
F
T
Site 49
T563
T
C
I
S
K
S
F
T
T
R
N
Q
V
E
P
Site 50
S572
R
N
Q
V
E
P
V
S
Q
T
T
D
N
N
S
Site 51
S579
S
Q
T
T
D
N
N
S
D
E
E
D
S
G
T
Site 52
S584
N
N
S
D
E
E
D
S
G
T
G
E
S
V
M
Site 53
T586
S
D
E
E
D
S
G
T
G
E
S
V
M
A
P
Site 54
S589
E
D
S
G
T
G
E
S
V
M
A
P
V
D
V
Site 55
S609
S
N
I
L
E
S
Y
S
S
Q
A
G
L
A
G
Site 56
S610
N
I
L
E
S
Y
S
S
Q
A
G
L
A
G
P
Site 57
T633
G
V
Q
L
P
D
N
T
D
H
R
P
T
S
K
Site 58
T638
D
N
T
D
H
R
P
T
S
K
P
T
K
N
_
Site 59
S639
N
T
D
H
R
P
T
S
K
P
T
K
N
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation