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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FTCD
Full Name:
Formimidoyltransferase-cyclodeaminase
Alias:
Formiminotransferase-cyclodeaminase;LCHC1;Glutamate formiminotransferase;Glutamate formyltransferase;Formiminotetrahydrofolate cyclodeaminase
Type:
Mass (Da):
58927
Number AA:
541
UniProt ID:
O95954
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T44
D
V
D
A
G
P
S
T
N
R
T
V
Y
T
F
Site 2
T47
A
G
P
S
T
N
R
T
V
Y
T
F
V
G
P
Site 3
Y49
P
S
T
N
R
T
V
Y
T
F
V
G
P
P
E
Site 4
T50
S
T
N
R
T
V
Y
T
F
V
G
P
P
E
C
Site 5
S70
L
N
A
A
R
V
A
S
R
L
I
D
M
S
R
Site 6
S76
A
S
R
L
I
D
M
S
R
H
Q
G
E
H
P
Site 7
Y124
E
E
L
D
V
P
V
Y
L
Y
G
E
A
A
R
Site 8
S134
G
E
A
A
R
M
D
S
R
R
T
L
P
A
I
Site 9
T137
A
R
M
D
S
R
R
T
L
P
A
I
R
A
G
Site 10
Y146
P
A
I
R
A
G
E
Y
E
A
L
P
K
K
L
Site 11
S166
A
P
D
F
G
P
S
S
F
V
P
S
W
G
A
Site 12
S170
G
P
S
S
F
V
P
S
W
G
A
T
A
T
G
Site 13
Y225
K
V
Q
G
I
G
W
Y
L
D
E
K
N
L
A
Site 14
T248
F
E
V
T
A
L
H
T
V
Y
E
E
T
C
R
Site 15
Y250
V
T
A
L
H
T
V
Y
E
E
T
C
R
E
A
Site 16
S261
C
R
E
A
Q
E
L
S
L
P
V
V
G
S
Q
Site 17
S316
L
D
S
L
C
P
F
S
P
K
E
R
I
I
E
Site 18
Y324
P
K
E
R
I
I
E
Y
L
V
P
E
R
G
P
Site 19
S339
E
R
G
L
G
S
K
S
L
R
A
F
V
G
E
Site 20
S351
V
G
E
V
G
A
R
S
A
A
P
G
G
G
S
Site 21
S358
S
A
A
P
G
G
G
S
V
A
A
A
A
A
A
Site 22
T378
G
S
M
V
G
L
M
T
Y
G
R
R
Q
F
Q
Site 23
Y379
S
M
V
G
L
M
T
Y
G
R
R
Q
F
Q
S
Site 24
S386
Y
G
R
R
Q
F
Q
S
L
D
T
T
M
R
R
Site 25
T389
R
Q
F
Q
S
L
D
T
T
M
R
R
L
I
P
Site 26
T390
Q
F
Q
S
L
D
T
T
M
R
R
L
I
P
P
Site 27
T406
R
E
A
S
A
K
L
T
T
L
V
D
A
D
A
Site 28
T429
A
M
R
L
P
K
N
T
P
E
E
K
D
R
R
Site 29
T437
P
E
E
K
D
R
R
T
A
A
L
Q
E
G
L
Site 30
T506
L
I
N
L
R
D
I
T
D
E
A
F
K
D
Q
Site 31
S519
D
Q
I
H
H
R
V
S
S
L
L
Q
E
A
K
Site 32
S520
Q
I
H
H
R
V
S
S
L
L
Q
E
A
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation