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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFEMP2
Full Name:
EGF-containing fibulin-like extracellular matrix protein 2
Alias:
FBLN4
Type:
Uncharacterized protein
Mass (Da):
49405
Number AA:
443
UniProt ID:
O95967
International Prot ID:
IPI00296058
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005604
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
L
L
L
L
G
S
A
S
P
Q
D
S
E
E
P
Site 2
S30
G
S
A
S
P
Q
D
S
E
E
P
D
S
Y
T
Site 3
S35
Q
D
S
E
E
P
D
S
Y
T
E
C
T
D
G
Site 4
Y36
D
S
E
E
P
D
S
Y
T
E
C
T
D
G
Y
Site 5
T37
S
E
E
P
D
S
Y
T
E
C
T
D
G
Y
E
Site 6
Y43
Y
T
E
C
T
D
G
Y
E
W
D
P
D
S
Q
Site 7
Y113
P
N
P
C
P
P
G
Y
E
P
D
D
Q
D
S
Site 8
T150
L
P
G
S
Y
Q
C
T
C
P
D
G
Y
R
K
Site 9
Y155
Q
C
T
C
P
D
G
Y
R
K
I
G
P
E
C
Site 10
Y221
E
Q
R
C
F
N
S
Y
G
T
F
L
C
R
C
Site 11
Y232
L
C
R
C
H
Q
G
Y
E
L
H
R
D
G
F
Site 12
S240
E
L
H
R
D
G
F
S
C
S
D
I
D
E
C
Site 13
S242
H
R
D
G
F
S
C
S
D
I
D
E
C
S
Y
Site 14
Y249
S
D
I
D
E
C
S
Y
S
S
Y
L
C
Q
Y
Site 15
Y252
D
E
C
S
Y
S
S
Y
L
C
Q
Y
R
C
I
Site 16
Y256
Y
S
S
Y
L
C
Q
Y
R
C
I
N
E
P
G
Site 17
S295
E
S
G
A
H
Q
C
S
E
A
Q
T
C
V
N
Site 18
Y307
C
V
N
F
H
G
G
Y
R
C
V
D
T
N
R
Site 19
Y319
T
N
R
C
V
E
P
Y
I
Q
V
S
E
N
R
Site 20
S342
L
C
R
E
Q
P
S
S
I
V
H
R
Y
M
T
Site 21
Y347
P
S
S
I
V
H
R
Y
M
T
I
T
S
E
R
Site 22
T349
S
I
V
H
R
Y
M
T
I
T
S
E
R
S
V
Site 23
T351
V
H
R
Y
M
T
I
T
S
E
R
S
V
P
A
Site 24
S352
H
R
Y
M
T
I
T
S
E
R
S
V
P
A
D
Site 25
Y369
Q
I
Q
A
T
S
V
Y
P
G
A
Y
N
A
F
Site 26
Y373
T
S
V
Y
P
G
A
Y
N
A
F
Q
I
R
A
Site 27
S383
F
Q
I
R
A
G
N
S
Q
G
D
F
Y
I
R
Site 28
Y388
G
N
S
Q
G
D
F
Y
I
R
Q
I
N
N
V
Site 29
Y426
T
M
N
S
L
M
S
Y
R
A
S
S
V
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation