PhosphoNET

           
Protein Info 
   
Short Name:  LGI1
Full Name:  Leucine-rich glioma-inactivated protein 1
Alias:  Epitempin-1
Type: 
Mass (Da):  63818
Number AA:  557
UniProt ID:  O95970
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y21IPLKRIAYFLCLLSA
Site 2S27AYFLCLLSALLLTEG
Site 3T32LLSALLLTEGKKPAK
Site 4S60ALCENARSIPRTVPP
Site 5T64NARSIPRTVPPDVIS
Site 6S83RSGFTEISEGSFLFT
Site 7Y119IGLPHLEYLFIENNN
Site 8T134IKSISRHTFRGLKSL
Site 9S164DIFKGLDSLTNVDLR
Site 10T166FKGLDSLTNVDLRGN
Site 11T194WLGHTNATVEDIYCE
Site 12Y199NATVEDIYCEGPPEY
Site 13Y206YCEGPPEYKKRKINS
Site 14S213YKKRKINSLSSKDFD
Site 15S215KRKINSLSSKDFDCI
Site 16S229IITEFAKSQDLPYQS
Site 17Y234AKSQDLPYQSLSIDT
Site 18S236SQDLPYQSLSIDTFS
Site 19S238DLPYQSLSIDTFSYL
Site 20T241YQSLSIDTFSYLNDE
Site 21S243SLSIDTFSYLNDEYV
Site 22Y275VEKTFRNYDNITGTS
Site 23Y309LFGGSHIYKRDSFAN
Site 24S313SHIYKRDSFANKFIK
Site 25T337RKPNDIETFKIENNW
Site 26Y345FKIENNWYFVVADSS
Site 27Y360KAGFTTIYKWNGNGF
Site 28Y368KWNGNGFYSHQSLHA
Site 29Y384YRDTDVEYLEIVRTP
Site 30T390EYLEIVRTPQTLRTP
Site 31T393EIVRTPQTLRTPHLI
Site 32T396RTPQTLRTPHLILSS
Site 33S402RTPHLILSSSSQRPV
Site 34S403TPHLILSSSSQRPVI
Site 35S404PHLILSSSSQRPVIY
Site 36S405HLILSSSSQRPVIYQ
Site 37Y411SSQRPVIYQWNKATQ
Site 38T424TQLFTNQTDIPNMED
Site 39S473QDIQRMPSRGSMVFQ
Site 40S476QRMPSRGSMVFQPLQ
Site 41Y487QPLQINNYQYAILGS
Site 42Y489LQINNYQYAILGSDY
Site 43S494YQYAILGSDYSFTQV
Site 44Y496YAILGSDYSFTQVYN
Site 45S524LNVQAPRSFTHVSIN
Site 46T526VQAPRSFTHVSINKR
Site 47S540RNFLFASSFKGNTQI
Site 48Y548FKGNTQIYKHVIVDL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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