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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BMP15
Full Name:
Bone morphogenetic protein 15
Alias:
BMP-15; Bone morphogenetic protein 15; GDF9B; GDF-9B; Growth/differentiation factor 9B
Type:
Secreted protein, Cytokine
Mass (Da):
45055
Number AA:
392
UniProt ID:
O95972
International Prot ID:
IPI00001485
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0005125
GO:0008083
PhosphoSite+
KinaseNET
Biological Process:
GO:0007292
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
I
E
E
L
L
E
E
S
P
G
E
Q
P
R
K
Site 2
S66
K
P
R
L
L
G
H
S
L
R
Y
M
L
E
L
Site 3
Y74
L
R
Y
M
L
E
L
Y
R
R
S
A
D
S
H
Site 4
S77
M
L
E
L
Y
R
R
S
A
D
S
H
G
H
P
Site 5
S80
L
Y
R
R
S
A
D
S
H
G
H
P
R
E
N
Site 6
T89
G
H
P
R
E
N
R
T
I
G
A
T
M
V
R
Site 7
T93
E
N
R
T
I
G
A
T
M
V
R
L
V
K
P
Site 8
T102
V
R
L
V
K
P
L
T
N
V
A
R
P
H
R
Site 9
T111
V
A
R
P
H
R
G
T
W
H
I
Q
I
L
G
Site 10
Y128
L
R
P
N
R
G
L
Y
Q
L
V
R
A
T
V
Site 11
S166
N
P
T
N
H
F
P
S
S
E
G
D
S
S
K
Site 12
S167
P
T
N
H
F
P
S
S
E
G
D
S
S
K
P
Site 13
S171
F
P
S
S
E
G
D
S
S
K
P
S
L
M
S
Site 14
S172
P
S
S
E
G
D
S
S
K
P
S
L
M
S
N
Site 15
S175
E
G
D
S
S
K
P
S
L
M
S
N
A
W
K
Site 16
S178
S
S
K
P
S
L
M
S
N
A
W
K
E
M
D
Site 17
Y235
D
I
A
F
L
L
L
Y
F
N
D
T
H
K
S
Site 18
T239
L
L
L
Y
F
N
D
T
H
K
S
I
R
K
A
Site 19
S261
E
E
F
M
E
R
E
S
L
L
R
R
T
R
Q
Site 20
T266
R
E
S
L
L
R
R
T
R
Q
A
D
G
I
S
Site 21
S273
T
R
Q
A
D
G
I
S
A
E
V
T
A
S
S
Site 22
T277
D
G
I
S
A
E
V
T
A
S
S
S
K
H
S
Site 23
S279
I
S
A
E
V
T
A
S
S
S
K
H
S
G
P
Site 24
S281
A
E
V
T
A
S
S
S
K
H
S
G
P
E
N
Site 25
S284
T
A
S
S
S
K
H
S
G
P
E
N
N
Q
C
Site 26
S292
G
P
E
N
N
Q
C
S
L
H
P
F
Q
I
S
Site 27
S299
S
L
H
P
F
Q
I
S
F
R
Q
L
G
W
D
Site 28
T316
I
I
A
P
P
F
Y
T
P
N
Y
C
K
G
T
Site 29
Y319
P
P
F
Y
T
P
N
Y
C
K
G
T
C
L
R
Site 30
S334
V
L
R
D
G
L
N
S
P
N
H
A
I
I
Q
Site 31
S351
I
N
Q
L
V
D
Q
S
V
P
R
P
S
C
V
Site 32
S356
D
Q
S
V
P
R
P
S
C
V
P
Y
K
Y
V
Site 33
Y360
P
R
P
S
C
V
P
Y
K
Y
V
P
I
S
V
Site 34
S366
P
Y
K
Y
V
P
I
S
V
L
M
I
E
A
N
Site 35
S375
L
M
I
E
A
N
G
S
I
L
Y
K
E
Y
E
Site 36
Y378
E
A
N
G
S
I
L
Y
K
E
Y
E
G
M
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation