PhosphoNET

           
Protein Info 
   
Short Name:  MBD3
Full Name:  Methyl-CpG-binding domain protein 3
Alias:  Methyl-CpG binding domain protein 3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
Type:  Transcription, coactivator/corepressor; Gene silencing
Mass (Da):  32844
Number AA:  291
UniProt ID:  O95983
International Prot ID:  IPI00439194
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016581  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0005515  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0006350  GO:0006350  GO:0006355 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S24REEVPRRSGLSAGHR
Site 2S27VPRRSGLSAGHRDVF
Site 3Y35AGHRDVFYYSPSGKK
Site 4Y36GHRDVFYYSPSGKKF
Site 5S37HRDVFYYSPSGKKFR
Site 6S39DVFYYSPSGKKFRSK
Site 7Y52SKPQLARYLGGSMDL
Site 8S56LARYLGGSMDLSTFD
Site 9S60LGGSMDLSTFDFRTG
Site 10T61GGSMDLSTFDFRTGK
Site 11T66LSTFDFRTGKMLMSK
Site 12S72RTGKMLMSKMNKSRQ
Site 13S77LMSKMNKSRQRVRYD
Site 14Y83KSRQRVRYDSSNQVK
Site 15S85RQRVRYDSSNQVKGK
Site 16S86QRVRYDSSNQVKGKP
Site 17T97KGKPDLNTALPVRQT
Site 18T104TALPVRQTASIFKQP
Site 19T113SIFKQPVTKITNHPS
Site 20T116KQPVTKITNHPSNKV
Site 21S120TKITNHPSNKVKSDP
Site 22S125HPSNKVKSDPQKAVD
Site 23S144LFWEKKLSGLNAFDI
Site 24S197MPITGQLSAAVEKNP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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