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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GAS8
Full Name:
Growth arrest-specific protein 8
Alias:
GAS11; Growth arrest-specific 11; Growth arrest-specific 8; Growth arrest-specific protein 11; Growth-arrest-specific protein 8
Type:
Cytoskeletal protein
Mass (Da):
56356
Number AA:
478
UniProt ID:
O95995
International Prot ID:
IPI00016076
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005929
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008285
GO:0030317
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
K
K
G
K
A
K
G
T
P
I
V
D
G
L
A
Site 2
S27
G
L
A
P
E
D
M
S
K
E
Q
V
E
E
H
Site 3
S36
E
Q
V
E
E
H
V
S
R
I
R
E
E
L
D
Site 4
Y51
R
E
R
E
E
R
N
Y
F
Q
L
E
R
D
K
Site 5
T61
L
E
R
D
K
I
H
T
F
W
E
I
T
R
R
Site 6
Y98
H
Q
V
E
I
K
V
Y
K
Q
K
V
K
H
L
Site 7
Y107
Q
K
V
K
H
L
L
Y
E
H
Q
N
N
L
T
Site 8
T121
T
E
M
K
A
E
G
T
V
V
M
K
L
A
Q
Site 9
S136
K
E
H
R
I
Q
E
S
V
L
R
K
D
M
R
Site 10
Y189
V
R
E
I
E
A
K
Y
D
K
K
M
K
M
L
Site 11
T206
E
L
D
L
R
R
K
T
E
L
H
E
V
E
E
Site 12
T231
Q
R
H
E
E
A
F
T
D
I
K
N
Y
Y
N
Site 13
Y236
A
F
T
D
I
K
N
Y
Y
N
D
I
T
L
N
Site 14
Y237
F
T
D
I
K
N
Y
Y
N
D
I
T
L
N
N
Site 15
S250
N
N
L
A
L
I
N
S
L
K
E
Q
M
E
D
Site 16
S291
Q
K
A
R
E
E
M
S
E
M
Q
K
Q
L
A
Site 17
Y300
M
Q
K
Q
L
A
N
Y
E
R
D
K
Q
I
L
Site 18
T336
E
V
L
E
Q
R
F
T
K
V
Q
Q
E
R
D
Site 19
Y346
Q
Q
E
R
D
E
L
Y
R
K
F
T
A
A
I
Site 20
T350
D
E
L
Y
R
K
F
T
A
A
I
Q
E
V
Q
Site 21
T400
N
L
D
P
A
A
L
T
L
V
S
R
K
L
E
Site 22
S415
D
V
L
E
S
K
N
S
T
I
K
D
L
Q
Y
Site 23
T416
V
L
E
S
K
N
S
T
I
K
D
L
Q
Y
E
Site 24
Y422
S
T
I
K
D
L
Q
Y
E
L
A
Q
V
C
K
Site 25
Y438
H
N
D
L
L
R
T
Y
E
A
K
L
L
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation