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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
APBA3
Full Name:
Amyloid beta A4 precursor protein-binding family A member 3
Alias:
Adapter protein X11gamma; Amyloid beta (A4) precursor protein-binding, family A, member 3; MINT3; Mint-3; Neuronal Munc18-1-interacting protein 3; Neuron-specific X11L2 protein; X11L2; X11-like 2
Type:
Mass (Da):
61450
Number AA:
UniProt ID:
O96018
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
F
P
T
I
S
R
S
P
S
G
P
P
Site 2
S9
D
F
P
T
I
S
R
S
P
S
G
P
P
A
M
Site 3
S11
P
T
I
S
R
S
P
S
G
P
P
A
M
D
L
Site 4
S28
P
R
D
I
L
V
P
S
E
D
L
T
P
D
S
Site 5
T32
L
V
P
S
E
D
L
T
P
D
S
Q
W
D
P
Site 6
S35
S
E
D
L
T
P
D
S
Q
W
D
P
M
P
G
Site 7
S46
P
M
P
G
G
P
G
S
L
S
R
M
E
L
D
Site 8
S48
P
G
G
P
G
S
L
S
R
M
E
L
D
E
S
Site 9
S55
S
R
M
E
L
D
E
S
S
L
Q
E
L
V
Q
Site 10
S56
R
M
E
L
D
E
S
S
L
Q
E
L
V
Q
Q
Site 11
S75
P
G
D
L
V
G
P
S
P
G
G
A
P
C
P
Site 12
S93
A
T
G
H
G
L
A
S
Q
E
I
A
D
A
H
Site 13
S104
A
D
A
H
G
L
L
S
A
E
A
G
R
D
D
Site 14
S124
H
C
E
E
C
P
P
S
Q
T
G
P
E
E
P
Site 15
S149
P
E
D
P
D
E
D
S
D
S
P
E
W
V
E
Site 16
S151
D
P
D
E
D
S
D
S
P
E
W
V
E
G
A
Site 17
S165
A
S
A
E
Q
E
G
S
R
S
S
S
S
S
P
Site 18
S167
A
E
Q
E
G
S
R
S
S
S
S
S
P
E
P
Site 19
S168
E
Q
E
G
S
R
S
S
S
S
S
P
E
P
W
Site 20
S169
Q
E
G
S
R
S
S
S
S
S
P
E
P
W
L
Site 21
S170
E
G
S
R
S
S
S
S
S
P
E
P
W
L
E
Site 22
S171
G
S
R
S
S
S
S
S
P
E
P
W
L
E
T
Site 23
T178
S
P
E
P
W
L
E
T
V
P
L
V
T
P
E
Site 24
T183
L
E
T
V
P
L
V
T
P
E
E
P
P
A
G
Site 25
S193
E
P
P
A
G
A
Q
S
P
E
T
L
A
S
Y
Site 26
T196
A
G
A
Q
S
P
E
T
L
A
S
Y
P
A
P
Site 27
S199
Q
S
P
E
T
L
A
S
Y
P
A
P
Q
E
V
Site 28
Y200
S
P
E
T
L
A
S
Y
P
A
P
Q
E
V
P
Site 29
Y225
G
V
I
F
G
A
R
Y
L
G
S
T
Q
L
V
Site 30
S228
F
G
A
R
Y
L
G
S
T
Q
L
V
S
E
R
Site 31
T229
G
A
R
Y
L
G
S
T
Q
L
V
S
E
R
N
Site 32
S233
L
G
S
T
Q
L
V
S
E
R
N
P
P
T
S
Site 33
S240
S
E
R
N
P
P
T
S
T
R
M
A
Q
A
R
Site 34
T264
D
G
E
T
Q
P
M
T
E
V
D
L
F
V
S
Site 35
T279
T
K
R
I
K
V
L
T
A
D
S
Q
E
A
M
Site 36
S282
I
K
V
L
T
A
D
S
Q
E
A
M
M
D
H
Site 37
Y326
Q
D
H
G
R
R
L
Y
K
M
L
C
H
V
F
Site 38
S354
Q
A
F
A
A
A
Y
S
Q
F
L
R
E
S
G
Site 39
S360
Y
S
Q
F
L
R
E
S
G
I
D
P
S
Q
V
Site 40
S365
R
E
S
G
I
D
P
S
Q
V
G
V
H
P
S
Site 41
S372
S
Q
V
G
V
H
P
S
P
G
A
C
H
L
H
Site 42
S387
N
G
D
L
D
H
F
S
N
S
D
N
C
R
E
Site 43
S435
H
G
G
P
A
E
R
S
G
A
L
S
I
G
D
Site 44
S439
A
E
R
S
G
A
L
S
I
G
D
R
L
T
A
Site 45
T467
C
Q
A
A
V
R
E
T
K
S
Q
T
S
V
T
Site 46
S469
A
A
V
R
E
T
K
S
Q
T
S
V
T
L
S
Site 47
S472
R
E
T
K
S
Q
T
S
V
T
L
S
I
V
H
Site 48
T474
T
K
S
Q
T
S
V
T
L
S
I
V
H
C
P
Site 49
T537
N
G
Q
S
V
V
A
T
P
H
A
R
I
I
E
Site 50
T557
Y
G
E
V
H
I
K
T
M
P
A
A
T
Y
R
Site 51
T567
A
A
T
Y
R
L
L
T
G
Q
E
Q
P
V
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation