PhosphoNET

           
Protein Info 
   
Short Name:  ADH1B
Full Name:  Alcohol dehydrogenase 1B
Alias:  ADH, beta subunit; ADH2; Alcohol dehydrogenase 1B (class I), beta polypeptide; Alcohol dehydrogenase 2; Alcohol dehydrogenase beta chain; Aldehyde reductase; EC 1.1.1.1
Type:  Enzyme - Dehydrogenase
Mass (Da):  39855
Number AA:  375
UniProt ID:  P00325
International Prot ID:  IPI00473031
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0004022  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0006069  GO:0055114   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S23WEVKKPFSIEDVEVA
Site 2Y35EVAPPKAYEVRIKMV
Site 3T83SVGEGVTTVKPGDKV
Site 4T95DKVIPLFTPQCGKCR
Site 5Y111CKNPESNYCLKNDLG
Site 6T123DLGNPRGTLQDGTRR
Site 7T128RGTLQDGTRRFTCRG
Site 8T132QDGTRRFTCRGKPIH
Site 9T144PIHHFLGTSTFSQYT
Site 10Y150GTSTFSQYTVVDENA
Site 11T151TSTFSQYTVVDENAV
Site 12T179LIGCGFSTGYGSAVN
Site 13Y181GCGFSTGYGSAVNVA
Site 14T239KAKELGATECINPQD
Site 15Y247ECINPQDYKKPIQEV
Site 16Y320RTWKGAVYGGFKSKE
Site 17S325AVYGGFKSKEGIPKL
Site 18S342DFMAKKFSLDALITH
Site 19S365EGFDLLHSGKSIRTV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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