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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
F13A1
Full Name:
Coagulation factor XIII A chain
Alias:
Coagulation factor XIII A chain precursor; Coagulation factor XIII, A1 polypeptide; Coagulation factor XIIIa; EC 2.3.2.13; F13A; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain
Type:
EC 2.3.2.13; Transferase
Mass (Da):
83136
Number AA:
731
UniProt ID:
P00488
International Prot ID:
IPI00297550
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0031093
Uniprot
OncoNet
Molecular Function:
GO:0008415
GO:0005509
GO:0003810
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
E
T
S
R
T
A
F
G
G
R
R
A
Site 2
T67
T
N
K
V
D
H
H
T
D
K
Y
E
N
N
K
Site 3
Y70
V
D
H
H
T
D
K
Y
E
N
N
K
L
I
V
Site 4
Y84
V
R
R
G
Q
S
F
Y
V
Q
I
D
F
S
R
Site 5
S90
F
Y
V
Q
I
D
F
S
R
P
Y
D
P
R
R
Site 6
Y93
Q
I
D
F
S
R
P
Y
D
P
R
R
D
L
F
Site 7
Y104
R
D
L
F
R
V
E
Y
V
I
G
R
Y
P
Q
Site 8
Y109
V
E
Y
V
I
G
R
Y
P
Q
E
N
K
G
T
Site 9
T116
Y
P
Q
E
N
K
G
T
Y
I
P
V
P
I
V
Site 10
S128
P
I
V
S
E
L
Q
S
G
K
W
G
A
K
I
Site 11
S142
I
V
M
R
E
D
R
S
V
R
L
S
I
Q
S
Site 12
S146
E
D
R
S
V
R
L
S
I
Q
S
S
P
K
C
Site 13
S174
P
Y
G
V
L
R
T
S
R
N
P
E
T
D
T
Site 14
T179
R
T
S
R
N
P
E
T
D
T
Y
I
L
F
N
Site 15
T181
S
R
N
P
E
T
D
T
Y
I
L
F
N
P
W
Site 16
Y182
R
N
P
E
T
D
T
Y
I
L
F
N
P
W
C
Site 17
Y195
W
C
E
D
D
A
V
Y
L
D
N
E
K
E
R
Site 18
Y205
N
E
K
E
R
E
E
Y
V
L
N
D
I
G
V
Site 19
T223
G
E
V
N
D
I
K
T
R
S
W
S
Y
G
Q
Site 20
S227
D
I
K
T
R
S
W
S
Y
G
Q
F
E
D
G
Site 21
S251
D
R
A
Q
M
D
L
S
G
R
G
N
P
I
K
Site 22
S260
R
G
N
P
I
K
V
S
R
V
G
S
A
M
V
Site 23
S264
I
K
V
S
R
V
G
S
A
M
V
N
A
K
D
Site 24
Y284
V
G
S
W
D
N
I
Y
A
Y
G
V
P
P
S
Site 25
Y286
S
W
D
N
I
Y
A
Y
G
V
P
P
S
A
W
Site 26
S291
Y
A
Y
G
V
P
P
S
A
W
T
G
S
V
D
Site 27
Y303
S
V
D
I
L
L
E
Y
R
S
S
E
N
P
V
Site 28
S305
D
I
L
L
E
Y
R
S
S
E
N
P
V
R
Y
Site 29
S306
I
L
L
E
Y
R
S
S
E
N
P
V
R
Y
G
Site 30
T337
G
I
P
A
R
I
V
T
N
Y
F
S
A
H
D
Site 31
Y339
P
A
R
I
V
T
N
Y
F
S
A
H
D
N
D
Site 32
S363
E
E
D
G
N
V
N
S
K
L
T
K
D
S
V
Site 33
S398
G
G
W
Q
A
V
D
S
T
P
Q
E
N
S
D
Site 34
T399
G
W
Q
A
V
D
S
T
P
Q
E
N
S
D
G
Site 35
Y408
Q
E
N
S
D
G
M
Y
R
C
G
P
A
S
V
Site 36
Y442
E
V
N
S
D
L
I
Y
I
T
A
K
K
D
G
Site 37
T450
I
T
A
K
K
D
G
T
H
V
V
E
N
V
D
Site 38
Y482
M
M
D
I
T
D
T
Y
K
F
Q
E
G
Q
E
Site 39
S515
N
T
E
G
V
M
K
S
R
S
N
V
D
M
D
Site 40
S517
E
G
V
M
K
S
R
S
N
V
D
M
D
F
E
Site 41
S537
L
G
K
D
F
K
L
S
I
T
F
R
N
N
S
Site 42
T539
K
D
F
K
L
S
I
T
F
R
N
N
S
H
N
Site 43
Y548
R
N
N
S
H
N
R
Y
T
I
T
A
Y
L
S
Site 44
T549
N
N
S
H
N
R
Y
T
I
T
A
Y
L
S
A
Site 45
T551
S
H
N
R
Y
T
I
T
A
Y
L
S
A
N
I
Site 46
T573
K
A
E
F
K
K
E
T
F
D
V
T
L
E
P
Site 47
T577
K
K
E
T
F
D
V
T
L
E
P
L
S
F
K
Site 48
T610
A
S
L
H
F
F
V
T
A
R
I
N
E
T
R
Site 49
S625
D
V
L
A
K
Q
K
S
T
V
L
T
I
P
E
Site 50
S645
R
G
T
Q
V
V
G
S
D
M
T
V
T
V
Q
Site 51
S688
F
R
E
I
R
P
N
S
T
V
Q
W
E
E
V
Site 52
T689
R
E
I
R
P
N
S
T
V
Q
W
E
E
V
C
Site 53
S709
G
H
R
K
L
I
A
S
M
S
S
D
S
L
R
Site 54
S711
R
K
L
I
A
S
M
S
S
D
S
L
R
H
V
Site 55
S714
I
A
S
M
S
S
D
S
L
R
H
V
Y
G
E
Site 56
Y719
S
D
S
L
R
H
V
Y
G
E
L
D
V
Q
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation