PhosphoNET

           
Protein Info 
   
Short Name:  HPRT1
Full Name:  Hypoxanthine-guanine phosphoribosyltransferase
Alias:  HGPRT
Type: 
Mass (Da):  24561
Number AA:  218
UniProt ID:  P00492
International Prot ID:  IPI00218493
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005829  GO:0044424 Uniprot OncoNet
Molecular Function:  GO:0000287  GO:0003824  GO:0004422 PhosphoSite+ KinaseNET
Biological Process:  GO:0006139  GO:0006144  GO:0006163 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11RSPGVVISDDEPGYD
Site 2Y17ISDDEPGYDLDLFCI
Site 3T46HGLIMDRTERLARDV
Site 4S89IKALNRNSDRSIPMT
Site 5S92LNRNSDRSIPMTVDF
Site 6T96SDRSIPMTVDFIRLK
Site 7S104VDFIRLKSYCNDQST
Site 8Y105DFIRLKSYCNDQSTG
Site 9T111SYCNDQSTGDIKVIG
Site 10T124IGGDDLSTLTGKNVL
Site 11T126GDDLSTLTGKNVLIV
Site 12T142DIIDTGKTMQTLLSL
Site 13T145DTGKTMQTLLSLVRQ
Site 14S148KTMQTLLSLVRQYNP
Site 15T168ASLLVKRTPRSVGYK
Site 16S171LVKRTPRSVGYKPDF
Site 17Y174RTPRSVGYKPDFVGF
Site 18Y195VVGYALDYNEYFRDL
Site 19Y198YALDYNEYFRDLNHV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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