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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Plasminogen
Full Name:
Plasminogen
Alias:
Type:
Protease
Mass (Da):
90569
Number AA:
810
UniProt ID:
P00747
International Prot ID:
IPI00019580
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0034185
GO:0005509
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
GO:0042730
GO:0006917
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
Q
G
E
P
L
D
D
Y
V
N
T
Q
G
A
S
Site 2
T28
P
L
D
D
Y
V
N
T
Q
G
A
S
L
F
S
Site 3
S35
T
Q
G
A
S
L
F
S
V
T
K
K
Q
L
G
Site 4
S82
I
M
A
E
N
R
K
S
S
I
I
I
R
M
R
Site 5
S83
M
A
E
N
R
K
S
S
I
I
I
R
M
R
D
Site 6
Y99
V
L
F
E
K
K
V
Y
L
S
E
C
K
T
G
Site 7
S101
F
E
K
K
V
Y
L
S
E
C
K
T
G
N
G
Site 8
T105
V
Y
L
S
E
C
K
T
G
N
G
K
N
Y
R
Site 9
Y111
K
T
G
N
G
K
N
Y
R
G
T
M
S
K
T
Site 10
T114
N
G
K
N
Y
R
G
T
M
S
K
T
K
N
G
Site 11
S116
K
N
Y
R
G
T
M
S
K
T
K
N
G
I
T
Site 12
T118
Y
R
G
T
M
S
K
T
K
N
G
I
T
C
Q
Site 13
T123
S
K
T
K
N
G
I
T
C
Q
K
W
S
S
T
Site 14
T130
T
C
Q
K
W
S
S
T
S
P
H
R
P
R
F
Site 15
S131
C
Q
K
W
S
S
T
S
P
H
R
P
R
F
S
Site 16
S138
S
P
H
R
P
R
F
S
P
A
T
H
P
S
E
Site 17
T141
R
P
R
F
S
P
A
T
H
P
S
E
G
L
E
Site 18
Y151
S
E
G
L
E
E
N
Y
C
R
N
P
D
N
D
Site 19
Y175
D
P
E
K
R
Y
D
Y
C
D
I
L
E
C
E
Site 20
S189
E
E
E
C
M
H
C
S
G
E
N
Y
D
G
K
Site 21
Y193
M
H
C
S
G
E
N
Y
D
G
K
I
S
K
T
Site 22
S198
E
N
Y
D
G
K
I
S
K
T
M
S
G
L
E
Site 23
T200
Y
D
G
K
I
S
K
T
M
S
G
L
E
C
Q
Site 24
S202
G
K
I
S
K
T
M
S
G
L
E
C
Q
A
W
Site 25
S211
L
E
C
Q
A
W
D
S
Q
S
P
H
A
H
G
Site 26
Y219
Q
S
P
H
A
H
G
Y
I
P
S
K
F
P
N
Site 27
T263
L
C
D
I
P
R
C
T
T
P
P
P
S
S
G
Site 28
T264
C
D
I
P
R
C
T
T
P
P
P
S
S
G
P
Site 29
S268
R
C
T
T
P
P
P
S
S
G
P
T
Y
Q
C
Site 30
S269
C
T
T
P
P
P
S
S
G
P
T
Y
Q
C
L
Site 31
T272
P
P
P
S
S
G
P
T
Y
Q
C
L
K
G
T
Site 32
Y273
P
P
S
S
G
P
T
Y
Q
C
L
K
G
T
G
Site 33
T290
Y
R
G
N
V
A
V
T
V
S
G
H
T
C
Q
Site 34
T306
W
S
A
Q
T
P
H
T
H
N
R
T
P
E
N
Site 35
T310
T
P
H
T
H
N
R
T
P
E
N
F
P
C
K
Site 36
Y323
C
K
N
L
D
E
N
Y
C
R
N
P
D
G
K
Site 37
S351
W
E
Y
C
K
I
P
S
C
D
S
S
P
V
S
Site 38
S354
C
K
I
P
S
C
D
S
S
P
V
S
T
E
Q
Site 39
S355
K
I
P
S
C
D
S
S
P
V
S
T
E
Q
L
Site 40
S358
S
C
D
S
S
P
V
S
T
E
Q
L
A
P
T
Site 41
T359
C
D
S
S
P
V
S
T
E
Q
L
A
P
T
A
Site 42
T365
S
T
E
Q
L
A
P
T
A
P
P
E
L
T
P
Site 43
T371
P
T
A
P
P
E
L
T
P
V
V
Q
D
C
Y
Site 44
Y378
T
P
V
V
Q
D
C
Y
H
G
D
G
Q
S
Y
Site 45
S384
C
Y
H
G
D
G
Q
S
Y
R
G
T
S
S
T
Site 46
T388
D
G
Q
S
Y
R
G
T
S
S
T
T
T
T
G
Site 47
S389
G
Q
S
Y
R
G
T
S
S
T
T
T
T
G
K
Site 48
S390
Q
S
Y
R
G
T
S
S
T
T
T
T
G
K
K
Site 49
T391
S
Y
R
G
T
S
S
T
T
T
T
G
K
K
C
Site 50
T393
R
G
T
S
S
T
T
T
T
G
K
K
C
Q
S
Site 51
T394
G
T
S
S
T
T
T
T
G
K
K
C
Q
S
W
Site 52
S400
T
T
G
K
K
C
Q
S
W
S
S
M
T
P
H
Site 53
T412
T
P
H
R
H
Q
K
T
P
E
N
Y
P
N
A
Site 54
Y416
H
Q
K
T
P
E
N
Y
P
N
A
G
L
T
M
Site 55
Y425
N
A
G
L
T
M
N
Y
C
R
N
P
D
A
D
Site 56
Y448
D
P
S
V
R
W
E
Y
C
N
L
K
K
C
S
Site 57
T475
V
L
L
P
D
V
E
T
P
S
E
E
D
C
M
Site 58
S477
L
P
D
V
E
T
P
S
E
E
D
C
M
F
G
Site 59
T495
G
Y
R
G
K
R
A
T
T
V
T
G
T
P
C
Site 60
T496
Y
R
G
K
R
A
T
T
V
T
G
T
P
C
Q
Site 61
T498
G
K
R
A
T
T
V
T
G
T
P
C
Q
D
W
Site 62
T500
R
A
T
T
V
T
G
T
P
C
Q
D
W
A
A
Site 63
S514
A
Q
E
P
H
R
H
S
I
F
T
P
E
T
N
Site 64
T517
P
H
R
H
S
I
F
T
P
E
T
N
P
R
A
Site 65
T520
H
S
I
F
T
P
E
T
N
P
R
A
G
L
E
Site 66
Y530
R
A
G
L
E
K
N
Y
C
R
N
P
D
G
D
Site 67
Y552
T
T
N
P
R
K
L
Y
D
Y
C
D
V
P
Q
Site 68
Y554
N
P
R
K
L
Y
D
Y
C
D
V
P
Q
C
A
Site 69
S564
V
P
Q
C
A
A
P
S
F
D
C
G
K
P
Q
Site 70
S597
H
S
W
P
W
Q
V
S
L
R
T
R
F
G
M
Site 71
S627
A
A
H
C
L
E
K
S
P
R
P
S
S
Y
K
Site 72
S631
L
E
K
S
P
R
P
S
S
Y
K
V
I
L
G
Site 73
S632
E
K
S
P
R
P
S
S
Y
K
V
I
L
G
A
Site 74
Y633
K
S
P
R
P
S
S
Y
K
V
I
L
G
A
H
Site 75
S655
H
V
Q
E
I
E
V
S
R
L
F
L
E
P
T
Site 76
T678
L
S
S
P
A
V
I
T
D
K
V
I
P
A
C
Site 77
Y691
A
C
L
P
S
P
N
Y
V
V
A
D
R
T
E
Site 78
T702
D
R
T
E
C
F
I
T
G
W
G
E
T
Q
G
Site 79
T710
G
W
G
E
T
Q
G
T
F
G
A
G
L
L
K
Site 80
Y732
E
N
K
V
C
N
R
Y
E
F
L
N
G
R
V
Site 81
S741
F
L
N
G
R
V
Q
S
T
E
L
C
A
G
H
Site 82
T742
L
N
G
R
V
Q
S
T
E
L
C
A
G
H
L
Site 83
S755
H
L
A
G
G
T
D
S
C
Q
G
D
S
G
G
Site 84
Y772
V
C
F
E
K
D
K
Y
I
L
Q
G
V
T
S
Site 85
Y793
R
P
N
K
P
G
V
Y
V
R
V
S
R
F
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation