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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CA1
Full Name:
Carbonic anhydrase 1
Alias:
Carbonate dehydratase I;Carbonic anhydrase B;Carbonic anhydrase I
Type:
Mass (Da):
28870
Number AA:
261
UniProt ID:
P00915
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
S
P
D
W
G
Y
D
D
K
N
G
P
E
Site 2
Y21
P
E
Q
W
S
K
L
Y
P
I
A
N
G
N
N
Site 3
S30
I
A
N
G
N
N
Q
S
P
V
D
I
K
T
S
Site 4
T36
Q
S
P
V
D
I
K
T
S
E
T
K
H
D
T
Site 5
S44
S
E
T
K
H
D
T
S
L
K
P
I
S
V
S
Site 6
S49
D
T
S
L
K
P
I
S
V
S
Y
N
P
A
T
Site 7
S51
S
L
K
P
I
S
V
S
Y
N
P
A
T
A
K
Site 8
T56
S
V
S
Y
N
P
A
T
A
K
E
I
I
N
V
Site 9
S78
F
E
D
N
D
N
R
S
V
L
K
G
G
P
F
Site 10
S86
V
L
K
G
G
P
F
S
D
S
Y
R
L
F
Q
Site 11
S88
K
G
G
P
F
S
D
S
Y
R
L
F
Q
F
H
Site 12
Y89
G
G
P
F
S
D
S
Y
R
L
F
Q
F
H
F
Site 13
S106
G
S
T
N
E
H
G
S
E
H
T
V
D
G
V
Site 14
S126
L
H
V
A
H
W
N
S
A
K
Y
S
S
L
A
Site 15
S130
H
W
N
S
A
K
Y
S
S
L
A
E
A
A
S
Site 16
S131
W
N
S
A
K
Y
S
S
L
A
E
A
A
S
K
Site 17
S137
S
S
L
A
E
A
A
S
K
A
D
G
L
A
V
Site 18
T170
D
A
L
Q
A
I
K
T
K
G
K
R
A
P
F
Site 19
T178
K
G
K
R
A
P
F
T
N
F
D
P
S
T
L
Site 20
S183
P
F
T
N
F
D
P
S
T
L
L
P
S
S
L
Site 21
T184
F
T
N
F
D
P
S
T
L
L
P
S
S
L
D
Site 22
S188
D
P
S
T
L
L
P
S
S
L
D
F
W
T
Y
Site 23
S189
P
S
T
L
L
P
S
S
L
D
F
W
T
Y
P
Site 24
T194
P
S
S
L
D
F
W
T
Y
P
G
S
L
T
H
Site 25
Y195
S
S
L
D
F
W
T
Y
P
G
S
L
T
H
P
Site 26
T200
W
T
Y
P
G
S
L
T
H
P
P
L
Y
E
S
Site 27
S216
T
W
I
I
C
K
E
S
I
S
V
S
S
E
Q
Site 28
S220
C
K
E
S
I
S
V
S
S
E
Q
L
A
Q
F
Site 29
S229
E
Q
L
A
Q
F
R
S
L
L
S
N
V
E
G
Site 30
T249
M
Q
H
N
N
R
P
T
Q
P
L
K
G
R
T
Site 31
T256
T
Q
P
L
K
G
R
T
V
R
A
S
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation