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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Prolactin
Full Name:
Prolactin
Alias:
Prl
Type:
Cytokine; Secreted protein
Mass (Da):
25876
Number AA:
227
UniProt ID:
P01236
International Prot ID:
IPI00000871
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005179
GO:0005148
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0007166
GO:0007565
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T42
G
A
A
R
C
Q
V
T
L
R
D
L
F
D
R
Site 2
S54
F
D
R
A
V
V
L
S
H
Y
I
H
N
L
S
Site 3
Y56
R
A
V
V
L
S
H
Y
I
H
N
L
S
S
E
Site 4
S61
S
H
Y
I
H
N
L
S
S
E
M
F
S
E
F
Site 5
S62
H
Y
I
H
N
L
S
S
E
M
F
S
E
F
D
Site 6
S66
N
L
S
S
E
M
F
S
E
F
D
K
R
Y
T
Site 7
Y72
F
S
E
F
D
K
R
Y
T
H
G
R
G
F
I
Site 8
T73
S
E
F
D
K
R
Y
T
H
G
R
G
F
I
T
Site 9
T88
K
A
I
N
S
C
H
T
S
S
L
A
T
P
E
Site 10
S89
A
I
N
S
C
H
T
S
S
L
A
T
P
E
D
Site 11
T93
C
H
T
S
S
L
A
T
P
E
D
K
E
Q
A
Site 12
S118
L
I
V
S
I
L
R
S
W
N
E
P
L
Y
H
Site 13
Y124
R
S
W
N
E
P
L
Y
H
L
V
T
E
V
R
Site 14
T128
E
P
L
Y
H
L
V
T
E
V
R
G
M
Q
E
Site 15
S142
E
A
P
E
A
I
L
S
K
A
V
E
I
E
E
Site 16
S163
E
G
M
E
L
I
V
S
Q
V
H
P
E
T
K
Site 17
Y175
E
T
K
E
N
E
I
Y
P
V
W
S
G
L
P
Site 18
S179
N
E
I
Y
P
V
W
S
G
L
P
S
L
Q
M
Site 19
S183
P
V
W
S
G
L
P
S
L
Q
M
A
D
E
E
Site 20
S194
A
D
E
E
S
R
L
S
A
Y
Y
N
L
L
H
Site 21
Y196
E
E
S
R
L
S
A
Y
Y
N
L
L
H
C
L
Site 22
Y197
E
S
R
L
S
A
Y
Y
N
L
L
H
C
L
R
Site 23
S207
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Site 24
Y213
D
S
H
K
I
D
N
Y
L
K
L
L
K
C
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation