PhosphoNET

           
Protein Info 
   
Short Name:  TG
Full Name:  Thyroglobulin
Alias:  AITD3; TGN; THYG; Thyroglobulin
Type: 
Mass (Da):  304790
Number AA:  2768
UniProt ID:  P01266
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005179     PhosphoSite+ KinaseNET
Biological Process:  GO:0042446  GO:0007165   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T40PCELQRETAFLKQAD
Site 2Y48AFLKQADYVPQCAED
Site 3S78WCVGANGSEVLGSRQ
Site 4S83NGSEVLGSRQPGRPV
Site 5S94GRPVACLSFCQLQKQ
Site 6S106QKQQILLSGYINSTD
Site 7S111LLSGYINSTDTSYLP
Site 8T112LSGYINSTDTSYLPQ
Site 9Y116INSTDTSYLPQCQDS
Site 10S123YLPQCQDSGDYAPVQ
Site 11Y126QCQDSGDYAPVQCDV
Site 12Y149DAEGMEVYGTRQLGR
Site 13T151EGMEVYGTRQLGRPK
Site 14S163RPKRCPRSCEIRNRR
Site 15S179LHGVGDKSPPQCSAE
Site 16S184DKSPPQCSAEGEFMP
Site 17Y211IFDLVHSYNRFPDAF
Site 18T220RFPDAFVTFSSFQRR
Site 19S222PDAFVTFSSFQRRFP
Site 20S223DAFVTFSSFQRRFPE
Site 21Y234RFPEVSGYCHCADSQ
Site 22S240GYCHCADSQGRELAE
Site 23T248QGRELAETGLELLLD
Site 24T275PSTFTETTLYRILQR
Site 25Y277TFTETTLYRILQRRF
Site 26S289RRFLAVQSVISGRFR
Site 27T299SGRFRCPTKCEVERF
Site 28T307KCEVERFTATSFGHP
Site 29S310VERFTATSFGHPYVP
Site 30Y315ATSFGHPYVPSCRRN
Site 31Y325SCRRNGDYQAVQCQT
Site 32T349QGKEMHGTRQQGEPP
Site 33S357RQQGEPPSCAEGQSC
Site 34S363PSCAEGQSCASERQQ
Site 35S373SERQQALSRLYFGTS
Site 36Y376QQALSRLYFGTSGYF
Site 37T379LSRLYFGTSGYFSQH
Site 38S380SRLYFGTSGYFSQHD
Site 39Y382LYFGTSGYFSQHDLF
Site 40S384FGTSGYFSQHDLFSS
Site 41S390FSQHDLFSSPEKRWA
Site 42S391SQHDLFSSPEKRWAS
Site 43S398SPEKRWASPRVARFA
Site 44T406PRVARFATSCPPTIK
Site 45S430RPMVEGQSQQFSVSE
Site 46S434EGQSQQFSVSENLLK
Site 47S436QSQQFSVSENLLKEA
Site 48T461ARLALQFTTNPKRLQ
Site 49S486NVGQFNLSGALGTRG
Site 50S498TRGTFNFSQFFQQLG
Site 51S508FQQLGLASFLNGGRQ
Site 52S523EDLAKPLSVGLDSNS
Site 53S528PLSVGLDSNSSTGTP
Site 54S530SVGLDSNSSTGTPEA
Site 55T532GLDSNSSTGTPEAAK
Site 56T534DSNSSTGTPEAAKKD
Site 57T543EAAKKDGTMNKPTVG
Site 58T548DGTMNKPTVGSFGFE
Site 59S605VMETVLSSQTCEQTP
Site 60T611SSQTCEQTPERLFVP
Site 61S619PERLFVPSCTTEGSY
Site 62T621RLFVPSCTTEGSYED
Site 63Y626SCTTEGSYEDVQCFS
Site 64S649WGKELPGSRVRGGQP
Site 65T660GGQPRCPTDCEKQRA
Site 66S671KQRARMQSLMGSQPA
Site 67S675RMQSLMGSQPAGSTL
Site 68T716EGQAIPGTRSAIGKP
Site 69S718QAIPGTRSAIGKPKK
Site 70T728GKPKKCPTPCQLQSE
Site 71S734PTPCQLQSEQAFLRT
Site 72T741SEQAFLRTVQALLSN
Site 73S747RTVQALLSNSSMLPT
Site 74S750QALLSNSSMLPTLSD
Site 75T754SNSSMLPTLSDTYIP
Site 76S756SSMLPTLSDTYIPQC
Site 77T758MLPTLSDTYIPQCST
Site 78Y759LPTLSDTYIPQCSTD
Site 79Y785PEQVFELYQRWEAQN
Site 80T798QNKGQDLTPAKLLVK
Site 81Y825SLFIQSLYEAGQQDV
Site 82S837QDVFPVLSQYPSLQD
Site 83S877QILNGQLSQYPGSYS
Site 84Y879LNGQLSQYPGSYSDF
Site 85S882QLSQYPGSYSDFSTP
Site 86S884SQYPGSYSDFSTPLA
Site 87S887PGSYSDFSTPLAHFD
Site 88T888GSYSDFSTPLAHFDL
Site 89S913QELEGMRSEPSKLPT
Site 90S916EGMRSEPSKLPTCPG
Site 91T920SEPSKLPTCPGSCEE
Site 92S924KLPTCPGSCEEAKLR
Site 93S944RETEEIVSASNSSRF
Site 94S946TEEIVSASNSSRFPL
Site 95S948EIVSASNSSRFPLGE
Site 96S990AEQFLRGSDYAIRLA
Site 97Y992QFLRGSDYAIRLAAQ
Site 98S1000AIRLAAQSTLSFYQR
Site 99T1001IRLAAQSTLSFYQRR
Site 100S1003LAAQSTLSFYQRRRF
Site 101Y1005AQSTLSFYQRRRFSP
Site 102S1011FYQRRRFSPDDSAGA
Site 103S1015RRFSPDDSAGASALL
Site 104S1019PDDSAGASALLRSGP
Site 105S1024GASALLRSGPYMPQC
Site 106S1062KGGFIPGSLTARSLQ
Site 107S1067PGSLTARSLQIPQCP
Site 108T1076QIPQCPTTCEKSRTS
Site 109S1080CPTTCEKSRTSGLLS
Site 110T1082TTCEKSRTSGLLSSW
Site 111S1083TCEKSRTSGLLSSWK
Site 112S1087SRTSGLLSSWKQARS
Site 113S1088RTSGLLSSWKQARSQ
Site 114S1094SSWKQARSQENPSPK
Site 115S1099ARSQENPSPKDLFVP
Site 116Y1114ACLETGEYARLQASG
Site 117S1131TWCVDPASGEELRPG
Site 118S1139GEELRPGSSSSAQCP
Site 119S1140EELRPGSSSSAQCPS
Site 120S1141ELRPGSSSSAQCPSL
Site 121S1142LRPGSSSSAQCPSLC
Site 122S1147SSSAQCPSLCNVLKS
Site 123S1158VLKSGVLSRRVSPGY
Site 124Y1165SRRVSPGYVPACRAE
Site 125S1177RAEDGGFSPVQCDQA
Site 126T1201SGEEVPGTRVTGGQP
Site 127T1204EVPGTRVTGGQPACE
Site 128S1212GGQPACESPRCPLPF
Site 129S1240TISGPTGSAMQQCQL
Site 130S1253QLLCRQGSWSVFPPG
Site 131S1255LCRQGSWSVFPPGPL
Site 132S1265PPGPLICSLESGRWE
Site 133S1268PLICSLESGRWESQL
Site 134S1273LESGRWESQLPQPRA
Site 135Y1310GKMCSADYADLLQTF
Site 136S1370GVNVTWKSRLEDIPV
Site 137T1400KDLLGRFTDLIQSGS
Site 138S1405RFTDLIQSGSFQLHL
Site 139S1407TDLIQSGSFQLHLDS
Site 140S1414SFQLHLDSKTFPAET
Site 141T1416QLHLDSKTFPAETIR
Site 142T1421SKTFPAETIRFLQGD
Site 143T1436HFGTSPRTWFGCSEG
Site 144T1449EGFYQVLTSEASQDG
Site 145S1450GFYQVLTSEASQDGL
Site 146S1468KCPEGSYSQDEECIP
Site 147S1501PVGRTTISAGAFSQT
Site 148T1508SAGAFSQTHCVTDCQ
Site 149Y1529QCDQNGQYRASQKDR
Site 150S1532QNGQYRASQKDRGSG
Site 151S1538ASQKDRGSGKAFCVD
Site 152T1556RRLPWWETEAPLEDS
Site 153S1563TEAPLEDSQCLMMQK
Site 154S1577KFEKVPESKVIFDAN
Site 155S1596VRSKVPDSEFPVMQC
Site 156S1614CTEDEACSFFTVSTT
Site 157T1621SFFTVSTTEPEISCD
Site 158Y1630PEISCDFYAWTSDNV
Site 159S1652KRDALGNSKATSFGS
Site 160S1656LGNSKATSFGSLRCQ
Site 161S1659SKATSFGSLRCQVKV
Site 162S1673VRSHGQDSPAVYLKK
Site 163Y1677GQDSPAVYLKKGQGS
Site 164Y1782ATCPGVTYDQESHQV
Site 165S1801GDQEFIKSLTPLEGT
Site 166T1803QEFIKSLTPLEGTQD
Site 167T1811PLEGTQDTFTNFQQV
Site 168T1813EGTQDTFTNFQQVYL
Site 169Y1819FTNFQQVYLWKDSDM
Site 170S1824QVYLWKDSDMGSRPE
Site 171S1828WKDSDMGSRPESMGC
Site 172S1832DMGSRPESMGCRKDT
Site 173T1839SMGCRKDTVPRPASP
Site 174S1845DTVPRPASPTEAGLT
Site 175T1847VPRPASPTEAGLTTE
Site 176T1852SPTEAGLTTELFSPV
Site 177T1853PTEAGLTTELFSPVD
Site 178S1871VIVNGNQSLSSQKHW
Site 179S1874NGNQSLSSQKHWLFK
Site 180Y1965EDKVKNFYTRLPFQK
Site 181T1966DKVKNFYTRLPFQKL
Site 182S1985IRNKVPMSEKSISNG
Site 183S1990PMSEKSISNGFFECE
Site 184S2036SLGIQMCSEENGGAW
Site 185S2050WRILDCGSPDIEVHT
Site 186Y2058PDIEVHTYPFGWYQK
Site 187S2089PSLTEKVSLDSWQSL
Site 188S2092TEKVSLDSWQSLALS
Site 189S2132AVRDLCLSECSQHEA
Site 190Y2184REEATHIYRKPGISL
Site 191S2190IYRKPGISLLSYEAS
Site 192S2193KPGISLLSYEASVPS
Site 193S2200SYEASVPSVPISTHG
Site 194S2213HGRLLGRSQAIQVGT
Site 195S2254EPLNWTGSWDASKPR
Site 196S2263DASKPRASCWQPGTR
Site 197T2269ASCWQPGTRTSTSPG
Site 198S2272WQPGTRTSTSPGVSE
Site 199T2273QPGTRTSTSPGVSED
Site 200S2274PGTRTSTSPGVSEDC
Site 201S2278TSTSPGVSEDCLYLN
Site 202S2311NTMDREESEGWPAID
Site 203Y2335LIVVTASYRVGVFGF
Site 204S2347FGFLSSGSGEVSGNW
Site 205S2351SSGSGEVSGNWGLLD
Site 206S2381GGDPRRVSLAADRGG
Site 207T2402HLLTARATNSQLFRR
Site 208S2404LTARATNSQLFRRAV
Site 209S2425LSPAAVISHERAQQQ
Site 210S2445KEVSCPMSSSQEVVS
Site 211S2446EVSCPMSSSQEVVSC
Site 212S2452SSSQEVVSCLRQKPA
Site 213T2467NVLNDAQTKLLAVSG
Site 214S2499PARALKRSLWVEVDL
Site 215S2529AVKQFEESRGRTSSK
Site 216T2533FEESRGRTSSKTAFY
Site 217S2534EESRGRTSSKTAFYQ
Site 218S2535ESRGRTSSKTAFYQA
Site 219T2537RGRTSSKTAFYQALQ
Site 220S2546FYQALQNSLGGEDSD
Site 221S2552NSLGGEDSDARVEAA
Site 222T2561ARVEAAATWYYSLEH
Site 223Y2563VEAAATWYYSLEHST
Site 224S2565AAATWYYSLEHSTDD
Site 225Y2573LEHSTDDYASFSRAL
Site 226S2575HSTDDYASFSRALEN
Site 227Y2611ARGNVFMYHAPENYG
Site 228Y2617MYHAPENYGHGSLEL
Site 229S2621PENYGHGSLELLADV
Site 230Y2640GLPFYPAYEGQFSLE
Site 231S2645PAYEGQFSLEEKSLS
Site 232S2650QFSLEEKSLSLKIMQ
Site 233S2652SLEEKSLSLKIMQYF
Site 234Y2658LSLKIMQYFSHFIRS
Site 235Y2670IRSGNPNYPYEFSRK
Site 236Y2672SGNPNYPYEFSRKVP
Site 237T2680EFSRKVPTFATPWPD
Site 238T2683RKVPTFATPWPDFVP
Site 239Y2697PRAGGENYKEFSELL
Site 240S2716GLKKADCSFWSKYIS
Site 241S2719KADCSFWSKYISSLK
Site 242Y2721DCSFWSKYISSLKTS
Site 243S2723SFWSKYISSLKTSAD
Site 244S2724FWSKYISSLKTSADG
Site 245T2727KYISSLKTSADGAKG
Site 246S2728YISSLKTSADGAKGG
Site 247S2737DGAKGGQSAESEEEE
Site 248S2740KGGQSAESEEEELTA
Site 249T2746ESEEEELTAGSGLRE
Site 250S2757GLREDLLSLQEPGSK
Site 251S2763LSLQEPGSKTYSK__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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