KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
IGHG1
Full Name:
Ig gamma-1 chain C region
Alias:
Type:
Mass (Da):
36106
Number AA:
330
UniProt ID:
P01857
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
A
S
T
K
G
P
S
V
F
P
L
A
P
S
Site 2
S14
S
V
F
P
L
A
P
S
S
K
S
T
S
G
G
Site 3
S15
V
F
P
L
A
P
S
S
K
S
T
S
G
G
T
Site 4
S17
P
L
A
P
S
S
K
S
T
S
G
G
T
A
A
Site 5
S19
A
P
S
S
K
S
T
S
G
G
T
A
A
L
G
Site 6
T38
D
Y
F
P
E
P
V
T
V
S
W
N
S
G
A
Site 7
T47
S
W
N
S
G
A
L
T
S
G
V
H
T
F
P
Site 8
Y81
S
S
L
G
T
Q
T
Y
I
C
N
V
N
H
K
Site 9
S102
D
K
K
V
E
P
K
S
C
D
K
T
H
T
C
Site 10
T106
E
P
K
S
C
D
K
T
H
T
C
P
P
C
P
Site 11
T108
K
S
C
D
K
T
H
T
C
P
P
C
P
A
P
Site 12
T133
F
P
P
K
P
K
D
T
L
M
I
S
R
T
P
Site 13
S137
P
K
D
T
L
M
I
S
R
T
P
E
V
T
C
Site 14
S150
T
C
V
V
V
D
V
S
H
E
D
P
E
V
K
Site 15
Y161
P
E
V
K
F
N
W
Y
V
D
G
V
E
V
H
Site 16
T172
V
E
V
H
N
A
K
T
K
P
R
E
E
Q
Y
Site 17
S181
P
R
E
E
Q
Y
N
S
T
Y
R
V
V
S
V
Site 18
T182
R
E
E
Q
Y
N
S
T
Y
R
V
V
S
V
L
Site 19
Y183
E
E
Q
Y
N
S
T
Y
R
V
V
S
V
L
T
Site 20
Y202
D
W
L
N
G
K
E
Y
K
C
K
V
S
N
K
Site 21
S220
A
P
I
E
K
T
I
S
K
A
K
G
Q
P
R
Site 22
Y232
Q
P
R
E
P
Q
V
Y
T
L
P
P
S
R
D
Site 23
T233
P
R
E
P
Q
V
Y
T
L
P
P
S
R
D
E
Site 24
S237
Q
V
Y
T
L
P
P
S
R
D
E
L
T
K
N
Site 25
T242
P
P
S
R
D
E
L
T
K
N
Q
V
S
L
T
Site 26
Y274
N
G
Q
P
E
N
N
Y
K
T
T
P
P
V
L
Site 27
T276
Q
P
E
N
N
Y
K
T
T
P
P
V
L
D
S
Site 28
T277
P
E
N
N
Y
K
T
T
P
P
V
L
D
S
D
Site 29
Y290
S
D
G
S
F
F
L
Y
S
K
L
T
V
D
K
Site 30
T294
F
F
L
Y
S
K
L
T
V
D
K
S
R
W
Q
Site 31
S298
S
K
L
T
V
D
K
S
R
W
Q
Q
G
N
V
Site 32
Y319
H
E
A
L
H
N
H
Y
T
Q
K
S
L
S
L
Site 33
T320
E
A
L
H
N
H
Y
T
Q
K
S
L
S
L
S
Site 34
S323
H
N
H
Y
T
Q
K
S
L
S
L
S
P
G
K
Site 35
S325
H
Y
T
Q
K
S
L
S
L
S
P
G
K
_
_
Site 36
S327
T
Q
K
S
L
S
L
S
P
G
K
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation