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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGHG2
Full Name:
Ig gamma-2 chain C region
Alias:
Type:
Mass (Da):
35901
Number AA:
326
UniProt ID:
P01859
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
V
F
P
L
A
P
C
S
R
S
T
S
E
S
T
Site 2
S17
P
L
A
P
C
S
R
S
T
S
E
S
T
A
A
Site 3
T18
L
A
P
C
S
R
S
T
S
E
S
T
A
A
L
Site 4
S19
A
P
C
S
R
S
T
S
E
S
T
A
A
L
G
Site 5
S21
C
S
R
S
T
S
E
S
T
A
A
L
G
C
L
Site 6
T38
D
Y
F
P
E
P
V
T
V
S
W
N
S
G
A
Site 7
T47
S
W
N
S
G
A
L
T
S
G
V
H
T
F
P
Site 8
S74
S
V
V
T
V
P
S
S
N
F
G
T
Q
T
Y
Site 9
T78
V
P
S
S
N
F
G
T
Q
T
Y
T
C
N
V
Site 10
Y81
S
N
F
G
T
Q
T
Y
T
C
N
V
D
H
K
Site 11
T97
S
N
T
K
V
D
K
T
V
E
R
K
C
C
V
Site 12
T129
F
P
P
K
P
K
D
T
L
M
I
S
R
T
P
Site 13
S133
P
K
D
T
L
M
I
S
R
T
P
E
V
T
C
Site 14
S146
T
C
V
V
V
D
V
S
H
E
D
P
E
V
Q
Site 15
Y157
P
E
V
Q
F
N
W
Y
V
D
G
V
E
V
H
Site 16
S177
P
R
E
E
Q
F
N
S
T
F
R
V
V
S
V
Site 17
T178
R
E
E
Q
F
N
S
T
F
R
V
V
S
V
L
Site 18
Y198
D
W
L
N
G
K
E
Y
K
C
K
V
S
N
K
Site 19
T214
L
P
A
P
I
E
K
T
I
S
K
T
K
G
Q
Site 20
S216
A
P
I
E
K
T
I
S
K
T
K
G
Q
P
R
Site 21
Y228
Q
P
R
E
P
Q
V
Y
T
L
P
P
S
R
E
Site 22
T229
P
R
E
P
Q
V
Y
T
L
P
P
S
R
E
E
Site 23
S233
Q
V
Y
T
L
P
P
S
R
E
E
M
T
K
N
Site 24
S243
E
M
T
K
N
Q
V
S
L
T
C
L
V
K
G
Site 25
S254
L
V
K
G
F
Y
P
S
D
I
S
V
E
W
E
Site 26
S257
G
F
Y
P
S
D
I
S
V
E
W
E
S
N
G
Site 27
Y270
N
G
Q
P
E
N
N
Y
K
T
T
P
P
M
L
Site 28
T273
P
E
N
N
Y
K
T
T
P
P
M
L
D
S
D
Site 29
S279
T
T
P
P
M
L
D
S
D
G
S
F
F
L
Y
Site 30
S282
P
M
L
D
S
D
G
S
F
F
L
Y
S
K
L
Site 31
Y286
S
D
G
S
F
F
L
Y
S
K
L
T
V
D
K
Site 32
T290
F
F
L
Y
S
K
L
T
V
D
K
S
R
W
Q
Site 33
S294
S
K
L
T
V
D
K
S
R
W
Q
Q
G
N
V
Site 34
Y315
H
E
A
L
H
N
H
Y
T
Q
K
S
L
S
L
Site 35
T316
E
A
L
H
N
H
Y
T
Q
K
S
L
S
L
S
Site 36
S319
H
N
H
Y
T
Q
K
S
L
S
L
S
P
G
K
Site 37
S321
H
Y
T
Q
K
S
L
S
L
S
P
G
K
_
_
Site 38
S323
T
Q
K
S
L
S
L
S
P
G
K
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation