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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGHG4
Full Name:
Ig gamma-4 chain C region
Alias:
Type:
Mass (Da):
35941
Number AA:
327
UniProt ID:
P01861
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
V
F
P
L
A
P
C
S
R
S
T
S
E
S
T
Site 2
S17
P
L
A
P
C
S
R
S
T
S
E
S
T
A
A
Site 3
T18
L
A
P
C
S
R
S
T
S
E
S
T
A
A
L
Site 4
S19
A
P
C
S
R
S
T
S
E
S
T
A
A
L
G
Site 5
S21
C
S
R
S
T
S
E
S
T
A
A
L
G
C
L
Site 6
T38
D
Y
F
P
E
P
V
T
V
S
W
N
S
G
A
Site 7
T47
S
W
N
S
G
A
L
T
S
G
V
H
T
F
P
Site 8
T78
V
P
S
S
S
L
G
T
K
T
Y
T
C
N
V
Site 9
T80
S
S
S
L
G
T
K
T
Y
T
C
N
V
D
H
Site 10
Y81
S
S
L
G
T
K
T
Y
T
C
N
V
D
H
K
Site 11
S100
K
V
D
K
R
V
E
S
K
Y
G
P
P
C
P
Site 12
Y102
D
K
R
V
E
S
K
Y
G
P
P
C
P
S
C
Site 13
S108
K
Y
G
P
P
C
P
S
C
P
A
P
E
F
L
Site 14
T130
F
P
P
K
P
K
D
T
L
M
I
S
R
T
P
Site 15
S134
P
K
D
T
L
M
I
S
R
T
P
E
V
T
C
Site 16
S147
T
C
V
V
V
D
V
S
Q
E
D
P
E
V
Q
Site 17
Y158
P
E
V
Q
F
N
W
Y
V
D
G
V
E
V
H
Site 18
S178
P
R
E
E
Q
F
N
S
T
Y
R
V
V
S
V
Site 19
T179
R
E
E
Q
F
N
S
T
Y
R
V
V
S
V
L
Site 20
Y180
E
E
Q
F
N
S
T
Y
R
V
V
S
V
L
T
Site 21
Y199
D
W
L
N
G
K
E
Y
K
C
K
V
S
N
K
Site 22
S204
K
E
Y
K
C
K
V
S
N
K
G
L
P
S
S
Site 23
S210
V
S
N
K
G
L
P
S
S
I
E
K
T
I
S
Site 24
S211
S
N
K
G
L
P
S
S
I
E
K
T
I
S
K
Site 25
T215
L
P
S
S
I
E
K
T
I
S
K
A
K
G
Q
Site 26
S217
S
S
I
E
K
T
I
S
K
A
K
G
Q
P
R
Site 27
Y229
Q
P
R
E
P
Q
V
Y
T
L
P
P
S
Q
E
Site 28
T230
P
R
E
P
Q
V
Y
T
L
P
P
S
Q
E
E
Site 29
S234
Q
V
Y
T
L
P
P
S
Q
E
E
M
T
K
N
Site 30
S244
E
M
T
K
N
Q
V
S
L
T
C
L
V
K
G
Site 31
Y271
N
G
Q
P
E
N
N
Y
K
T
T
P
P
V
L
Site 32
T273
Q
P
E
N
N
Y
K
T
T
P
P
V
L
D
S
Site 33
T274
P
E
N
N
Y
K
T
T
P
P
V
L
D
S
D
Site 34
Y287
S
D
G
S
F
F
L
Y
S
R
L
T
V
D
K
Site 35
T291
F
F
L
Y
S
R
L
T
V
D
K
S
R
W
Q
Site 36
S295
S
R
L
T
V
D
K
S
R
W
Q
E
G
N
V
Site 37
Y316
H
E
A
L
H
N
H
Y
T
Q
K
S
L
S
L
Site 38
T317
E
A
L
H
N
H
Y
T
Q
K
S
L
S
L
S
Site 39
S320
H
N
H
Y
T
Q
K
S
L
S
L
S
L
G
K
Site 40
S322
H
Y
T
Q
K
S
L
S
L
S
L
G
K
_
_
Site 41
S324
T
Q
K
S
L
S
L
S
L
G
K
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation