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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGHM
Full Name:
Ig mu chain C region
Alias:
Type:
Mass (Da):
49307
Number AA:
452
UniProt ID:
P01871
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
T
L
F
P
L
V
S
C
E
N
S
P
S
D
Site 2
S17
P
L
V
S
C
E
N
S
P
S
D
T
S
S
V
Site 3
S19
V
S
C
E
N
S
P
S
D
T
S
S
V
A
V
Site 4
T21
C
E
N
S
P
S
D
T
S
S
V
A
V
G
C
Site 5
S22
E
N
S
P
S
D
T
S
S
V
A
V
G
C
L
Site 6
S37
A
Q
D
F
L
P
D
S
I
T
L
S
W
K
Y
Site 7
T39
D
F
L
P
D
S
I
T
L
S
W
K
Y
K
N
Site 8
S41
L
P
D
S
I
T
L
S
W
K
Y
K
N
N
S
Site 9
Y44
S
I
T
L
S
W
K
Y
K
N
N
S
D
I
S
Site 10
S48
S
W
K
Y
K
N
N
S
D
I
S
S
T
R
G
Site 11
S51
Y
K
N
N
S
D
I
S
S
T
R
G
F
P
S
Site 12
S52
K
N
N
S
D
I
S
S
T
R
G
F
P
S
V
Site 13
S58
S
S
T
R
G
F
P
S
V
L
R
G
G
K
Y
Site 14
T68
R
G
G
K
Y
A
A
T
S
Q
V
L
L
P
S
Site 15
S69
G
G
K
Y
A
A
T
S
Q
V
L
L
P
S
K
Site 16
T82
S
K
D
V
M
Q
G
T
D
E
H
V
V
C
K
Site 17
S114
A
E
L
P
P
K
V
S
V
F
V
P
P
R
D
Site 18
S140
I
C
Q
A
T
G
F
S
P
R
Q
I
Q
V
S
Site 19
S147
S
P
R
Q
I
Q
V
S
W
L
R
E
G
K
Q
Site 20
S157
R
E
G
K
Q
V
G
S
G
V
T
T
D
Q
V
Site 21
T161
Q
V
G
S
G
V
T
T
D
Q
V
Q
A
E
A
Site 22
S171
V
Q
A
E
A
K
E
S
G
P
T
T
Y
K
V
Site 23
T174
E
A
K
E
S
G
P
T
T
Y
K
V
T
S
T
Site 24
T175
A
K
E
S
G
P
T
T
Y
K
V
T
S
T
L
Site 25
Y176
K
E
S
G
P
T
T
Y
K
V
T
S
T
L
T
Site 26
T181
T
T
Y
K
V
T
S
T
L
T
I
K
E
S
D
Site 27
T183
Y
K
V
T
S
T
L
T
I
K
E
S
D
W
L
Site 28
S187
S
T
L
T
I
K
E
S
D
W
L
G
Q
S
M
Site 29
T205
R
V
D
H
R
G
L
T
F
Q
Q
N
A
S
S
Site 30
S254
T
D
L
T
T
Y
D
S
V
T
I
S
W
T
R
Site 31
T256
L
T
T
Y
D
S
V
T
I
S
W
T
R
Q
N
Site 32
S258
T
Y
D
S
V
T
I
S
W
T
R
Q
N
G
E
Site 33
T269
Q
N
G
E
A
V
K
T
H
T
N
I
S
E
S
Site 34
T271
G
E
A
V
K
T
H
T
N
I
S
E
S
H
P
Site 35
S276
T
H
T
N
I
S
E
S
H
P
N
A
T
F
S
Site 36
T281
S
E
S
H
P
N
A
T
F
S
A
V
G
E
A
Site 37
S283
S
H
P
N
A
T
F
S
A
V
G
E
A
S
I
Site 38
T304
S
G
E
R
F
T
C
T
V
T
H
T
D
L
P
Site 39
T306
E
R
F
T
C
T
V
T
H
T
D
L
P
S
P
Site 40
T308
F
T
C
T
V
T
H
T
D
L
P
S
P
L
K
Site 41
S312
V
T
H
T
D
L
P
S
P
L
K
Q
T
I
S
Site 42
S319
S
P
L
K
Q
T
I
S
R
P
K
G
V
A
L
Site 43
Y332
A
L
H
R
P
D
V
Y
L
L
P
P
A
R
E
Site 44
S373
M
Q
R
G
Q
P
L
S
P
E
K
Y
V
T
S
Site 45
Y377
Q
P
L
S
P
E
K
Y
V
T
S
A
P
M
P
Site 46
T379
L
S
P
E
K
Y
V
T
S
A
P
M
P
E
P
Site 47
Y392
E
P
Q
A
P
G
R
Y
F
A
H
S
I
L
T
Site 48
S396
P
G
R
Y
F
A
H
S
I
L
T
V
S
E
E
Site 49
T399
Y
F
A
H
S
I
L
T
V
S
E
E
E
W
N
Site 50
S401
A
H
S
I
L
T
V
S
E
E
E
W
N
T
G
Site 51
T407
V
S
E
E
E
W
N
T
G
E
T
Y
T
C
V
Site 52
Y411
E
W
N
T
G
E
T
Y
T
C
V
A
H
E
A
Site 53
T424
E
A
L
P
N
R
V
T
E
R
T
V
D
K
S
Site 54
T427
P
N
R
V
T
E
R
T
V
D
K
S
T
G
K
Site 55
S431
T
E
R
T
V
D
K
S
T
G
K
P
T
L
Y
Site 56
T432
E
R
T
V
D
K
S
T
G
K
P
T
L
Y
N
Site 57
T436
D
K
S
T
G
K
P
T
L
Y
N
V
S
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation