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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGHD
Full Name:
Ig delta chain C region
Alias:
Type:
Mass (Da):
42254
Number AA:
384
UniProt ID:
P01880
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
D
V
F
P
I
I
S
G
C
R
H
P
K
D
Site 2
S22
C
R
H
P
K
D
N
S
P
V
V
L
A
C
L
Site 3
T41
H
P
T
S
V
T
V
T
W
Y
M
G
T
Q
S
Site 4
T53
T
Q
S
Q
P
Q
R
T
F
P
E
I
Q
R
R
Site 5
S62
P
E
I
Q
R
R
D
S
Y
Y
M
T
S
S
Q
Site 6
Y63
E
I
Q
R
R
D
S
Y
Y
M
T
S
S
Q
L
Site 7
Y64
I
Q
R
R
D
S
Y
Y
M
T
S
S
Q
L
S
Site 8
T66
R
R
D
S
Y
Y
M
T
S
S
Q
L
S
T
P
Site 9
S67
R
D
S
Y
Y
M
T
S
S
Q
L
S
T
P
L
Site 10
S68
D
S
Y
Y
M
T
S
S
Q
L
S
T
P
L
Q
Site 11
S71
Y
M
T
S
S
Q
L
S
T
P
L
Q
Q
W
R
Site 12
T72
M
T
S
S
Q
L
S
T
P
L
Q
Q
W
R
Q
Site 13
Y82
Q
Q
W
R
Q
G
E
Y
K
C
V
V
Q
H
T
Site 14
S93
V
Q
H
T
A
S
K
S
K
K
E
I
F
R
W
Site 15
S103
E
I
F
R
W
P
E
S
P
K
A
Q
A
S
S
Site 16
S109
E
S
P
K
A
Q
A
S
S
V
P
T
A
Q
P
Site 17
T113
A
Q
A
S
S
V
P
T
A
Q
P
Q
A
E
G
Site 18
S121
A
Q
P
Q
A
E
G
S
L
A
K
A
T
T
A
Site 19
T126
E
G
S
L
A
K
A
T
T
A
P
A
T
T
R
Site 20
T131
K
A
T
T
A
P
A
T
T
R
N
T
G
R
G
Site 21
T135
A
P
A
T
T
R
N
T
G
R
G
G
E
E
K
Site 22
T156
E
E
Q
E
E
R
E
T
K
T
P
E
C
P
S
Site 23
T158
Q
E
E
R
E
T
K
T
P
E
C
P
S
H
T
Site 24
S224
E
G
L
L
E
R
H
S
N
G
S
Q
S
Q
H
Site 25
S227
L
E
R
H
S
N
G
S
Q
S
Q
H
S
R
L
Site 26
S229
R
H
S
N
G
S
Q
S
Q
H
S
R
L
T
L
Site 27
T235
Q
S
Q
H
S
R
L
T
L
P
R
S
L
W
N
Site 28
S239
S
R
L
T
L
P
R
S
L
W
N
A
G
T
S
Site 29
T250
A
G
T
S
V
T
C
T
L
N
H
P
S
L
P
Site 30
S255
T
C
T
L
N
H
P
S
L
P
P
Q
R
L
M
Site 31
S283
S
L
N
L
L
A
S
S
D
P
P
E
A
A
S
Site 32
S318
D
Q
R
E
V
N
T
S
G
F
A
P
A
R
P
Site 33
S331
R
P
P
P
Q
P
G
S
T
T
F
W
A
W
S
Site 34
T333
P
P
Q
P
G
S
T
T
F
W
A
W
S
V
L
Site 35
S347
L
R
V
P
A
P
P
S
P
Q
P
A
T
Y
T
Site 36
T352
P
P
S
P
Q
P
A
T
Y
T
C
V
V
S
H
Site 37
Y353
P
S
P
Q
P
A
T
Y
T
C
V
V
S
H
E
Site 38
T354
S
P
Q
P
A
T
Y
T
C
V
V
S
H
E
D
Site 39
S358
A
T
Y
T
C
V
V
S
H
E
D
S
R
T
L
Site 40
S362
C
V
V
S
H
E
D
S
R
T
L
L
N
A
S
Site 41
T364
V
S
H
E
D
S
R
T
L
L
N
A
S
R
S
Site 42
S369
S
R
T
L
L
N
A
S
R
S
L
E
V
S
Y
Site 43
S375
A
S
R
S
L
E
V
S
Y
V
T
D
H
G
P
Site 44
Y376
S
R
S
L
E
V
S
Y
V
T
D
H
G
P
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation