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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COL1A1
Full Name:
Collagen alpha-1(I) chain
Alias:
Alpha-1 type I collagen
Type:
Extracellular matrix protein
Mass (Da):
138911
Number AA:
1464
UniProt ID:
P02452
International Prot ID:
IPI00297646
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005578
GO:0005581
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005201
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0001501
GO:0003008
GO:0006412
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T39
D
E
D
I
P
P
I
T
C
V
Q
N
G
L
R
Site 2
T78
D
D
V
I
C
D
E
T
K
N
C
P
G
A
E
Site 3
S99
C
P
V
C
P
D
G
S
E
S
P
T
D
Q
E
Site 4
S101
V
C
P
D
G
S
E
S
P
T
D
Q
E
T
T
Site 5
T103
P
D
G
S
E
S
P
T
D
Q
E
T
T
G
V
Site 6
T107
E
S
P
T
D
Q
E
T
T
G
V
E
G
P
K
Site 7
T117
V
E
G
P
K
G
D
T
G
P
R
G
P
R
G
Site 8
S164
G
N
F
A
P
Q
L
S
Y
G
Y
D
E
K
S
Site 9
Y167
A
P
Q
L
S
Y
G
Y
D
E
K
S
T
G
G
Site 10
S171
S
Y
G
Y
D
E
K
S
T
G
G
I
S
V
P
Site 11
T172
Y
G
Y
D
E
K
S
T
G
G
I
S
V
P
G
Site 12
S176
E
K
S
T
G
G
I
S
V
P
G
P
M
G
P
Site 13
S184
V
P
G
P
M
G
P
S
G
P
R
G
L
P
G
Site 14
S214
E
P
G
E
P
G
A
S
G
P
M
G
P
R
G
Site 15
T258
G
A
R
G
L
P
G
T
A
G
L
P
G
M
K
Site 16
S271
M
K
G
H
R
G
F
S
G
L
D
G
A
K
G
Site 17
S291
G
P
K
G
E
P
G
S
P
G
E
N
G
A
P
Site 18
T328
A
R
G
N
D
G
A
T
G
A
A
G
P
P
G
Site 19
S363
G
P
Q
G
P
R
G
S
E
G
P
Q
G
V
R
Site 20
S418
F
P
G
A
R
G
P
S
G
P
Q
G
P
G
G
Site 21
S433
P
P
G
P
K
G
N
S
G
E
P
G
A
P
G
Site 22
S441
G
E
P
G
A
P
G
S
K
G
D
T
G
A
K
Site 23
T445
A
P
G
S
K
G
D
T
G
A
K
G
E
P
G
Site 24
T478
A
R
G
E
P
G
P
T
G
L
P
G
P
P
G
Site 25
S492
G
E
R
G
G
P
G
S
R
G
F
P
G
A
D
Site 26
S513
G
P
A
G
E
R
G
S
P
G
P
A
G
P
K
Site 27
S522
G
P
A
G
P
K
G
S
P
G
E
A
G
R
P
Site 28
T541
L
P
G
A
K
G
L
T
G
S
P
G
S
P
G
Site 29
S543
G
A
K
G
L
T
G
S
P
G
S
P
G
P
D
Site 30
S546
G
L
T
G
S
P
G
S
P
G
P
D
G
K
T
Site 31
T553
S
P
G
P
D
G
K
T
G
P
P
G
P
A
G
Site 32
S639
G
E
Q
G
P
A
G
S
P
G
F
Q
G
L
P
Site 33
S720
G
A
P
G
A
P
G
S
Q
G
A
P
G
L
Q
Site 34
S756
G
P
K
G
A
D
G
S
P
G
K
D
G
V
R
Site 35
T766
K
D
G
V
R
G
L
T
G
P
I
G
P
P
G
Site 36
S784
A
P
G
D
K
G
E
S
G
P
S
G
P
A
G
Site 37
S787
D
K
G
E
S
G
P
S
G
P
A
G
P
T
G
Site 38
S867
G
A
K
G
A
R
G
S
A
G
P
P
G
A
T
Site 39
S889
R
V
G
P
P
G
P
S
G
N
A
G
P
P
G
Site 40
T913
G
K
G
P
R
G
E
T
G
P
A
G
R
P
G
Site 41
S936
G
P
A
G
E
K
G
S
P
G
A
D
G
P
A
Site 42
T948
G
P
A
G
A
P
G
T
P
G
P
Q
G
I
A
Site 43
S979
F
P
G
L
P
G
P
S
G
E
P
G
K
Q
G
Site 44
S988
E
P
G
K
Q
G
P
S
G
A
S
G
E
R
G
Site 45
S991
K
Q
G
P
S
G
A
S
G
E
R
G
P
P
G
Site 46
S1012
L
A
G
P
P
G
E
S
G
R
E
G
A
P
G
Site 47
S1023
G
A
P
G
A
E
G
S
P
G
R
D
G
S
P
Site 48
S1029
G
S
P
G
R
D
G
S
P
G
A
K
G
D
R
Site 49
T1039
A
K
G
D
R
G
E
T
G
P
A
G
P
P
G
Site 50
S1063
P
V
G
P
A
G
K
S
G
D
R
G
E
T
G
Site 51
T1069
K
S
G
D
R
G
E
T
G
P
A
G
P
A
G
Site 52
S1114
I
K
G
H
R
G
F
S
G
L
Q
G
P
P
G
Site 53
S1125
G
P
P
G
P
P
G
S
P
G
E
Q
G
P
S
Site 54
S1132
S
P
G
E
Q
G
P
S
G
A
S
G
P
A
G
Site 55
S1135
E
Q
G
P
S
G
A
S
G
P
A
G
P
R
G
Site 56
S1146
G
P
R
G
P
P
G
S
A
G
A
P
G
K
D
Site 57
T1171
P
P
G
P
R
G
R
T
G
D
A
G
P
V
G
Site 58
S1193
P
G
P
P
G
P
P
S
A
G
F
D
F
S
F
Site 59
S1199
P
S
A
G
F
D
F
S
F
L
P
Q
P
P
Q
Site 60
Y1215
K
A
H
D
G
G
R
Y
Y
R
A
D
D
A
N
Site 61
Y1216
A
H
D
G
G
R
Y
Y
R
A
D
D
A
N
V
Site 62
T1233
D
R
D
L
E
V
D
T
T
L
K
S
L
S
Q
Site 63
T1234
R
D
L
E
V
D
T
T
L
K
S
L
S
Q
Q
Site 64
S1237
E
V
D
T
T
L
K
S
L
S
Q
Q
I
E
N
Site 65
S1239
D
T
T
L
K
S
L
S
Q
Q
I
E
N
I
R
Site 66
S1247
Q
Q
I
E
N
I
R
S
P
E
G
S
R
K
N
Site 67
S1251
N
I
R
S
P
E
G
S
R
K
N
P
A
R
T
Site 68
T1258
S
R
K
N
P
A
R
T
C
R
D
L
K
M
C
Site 69
Y1301
E
T
G
E
T
C
V
Y
P
T
Q
P
S
V
A
Site 70
Y1313
S
V
A
Q
K
N
W
Y
I
S
K
N
P
K
D
Site 71
Y1338
T
D
G
F
Q
F
E
Y
G
G
Q
G
S
D
P
Site 72
T1360
T
F
L
R
L
M
S
T
E
A
S
Q
N
I
T
Site 73
Y1368
E
A
S
Q
N
I
T
Y
H
C
K
N
S
V
A
Site 74
S1393
K
A
L
L
L
Q
G
S
N
E
I
E
I
R
A
Site 75
S1404
E
I
R
A
E
G
N
S
R
F
T
Y
S
V
T
Site 76
T1407
A
E
G
N
S
R
F
T
Y
S
V
T
V
D
G
Site 77
Y1408
E
G
N
S
R
F
T
Y
S
V
T
V
D
G
C
Site 78
S1409
G
N
S
R
F
T
Y
S
V
T
V
D
G
C
T
Site 79
T1411
S
R
F
T
Y
S
V
T
V
D
G
C
T
S
H
Site 80
T1425
H
T
G
A
W
G
K
T
V
I
E
Y
K
T
T
Site 81
Y1429
W
G
K
T
V
I
E
Y
K
T
T
K
T
S
R
Site 82
T1432
T
V
I
E
Y
K
T
T
K
T
S
R
L
P
I
Site 83
T1434
I
E
Y
K
T
T
K
T
S
R
L
P
I
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation